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CSNK1A1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS768252

MBS768252 is an antibody targeting CSNK1A1. Also known as CSNK1A1 Rabbit Polyclonal. Reactive in Human, Mouse, Rat. Host: Rabbit. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
CSNK1A1, Polyclonal Antibody
Full Product Name
CSNK1A1 Rabbit Polyclonal
Product Gene Name
anti-CSNK1A1 antibody
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid
Purity/Purification
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Preparation and Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)
Molecular Weight
37,567 Da
OMIM
600505
Immunogen
Casein kinase 1, alpha 1
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Applications Tested/Suitable for anti-CSNK1A1 antibody
ELISA (EIA), Western Blot (WB), Immunofluorescence (IF)

Western Blot (WB) of anti-CSNK1A1 antibody

MCF7 cells were subjected to SDS PAGE followed by western blot with MBS768252 (CSNK1A1 antibody) at dilution of 1:1000
Rabbit Anti-CSNK1A1 Polyclonal Antibody – Cat# MBS768252

Other Notes

Small volumes of anti-CSNK1A1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CSNK1A1. It may not necessarily be applicable to this product.

NCBI GI #
414144878
NCBI GeneID
1452
NCBI Accession #
NP_001258670.1
UniProt Secondary Accession #
Q4JJA0; Q5U046; Q5U047; Q6FGA2; Q71TU5; Q96HD2; Q9UDK3; D3DQG0; D3DQG1
UniProt Related Accession #
P48729
GenBank Nucleotide #
NM_001271741.1
NCBI Official Full Name
casein kinase I isoform alpha isoform 3
NCBI Official Synonym Full Names
casein kinase 1 alpha 1
NCBI Official Symbol
CSNK1A1
NCBI Official Synonym Symbols
CK1; CK1a; CKIa; HLCDGP1; PRO2975; HEL-S-77p
UniProt Protein Name
Casein kinase I isoform alpha
UniProt Synonym Protein Names
CK1
Protein Family
Casein kinase
UniProt Gene Name
CSNK1A1
UniProt Synonym Gene Names
CKI-alpha
UniProt Entry Name
KC1A_HUMAN
NCBI Protein Information
casein kinase I isoform alpha

UniProt Comments for CSNK1A1

CK1A: an ubiquitous protein kinase of the CK1 family. Participates in Wnt signaling. Phosphorylates beta catenin, marking it for beta-TRCp-mediated ubiquitinylation and proteasomal degradation.

Protein type: Kinase, protein; EC 2.7.11.1; Protein kinase, CK1; Protein kinase, Ser/Thr (non-receptor); CK1 group; CK1 family

Chromosomal Location of Human Ortholog: 5q32

Cellular Component: beta-catenin destruction complex; centrosome; cytosol; keratin filament; membrane; mRNA cleavage and polyadenylation specificity factor complex; nuclear speck

Molecular Function: ATP binding; kinase activity; protein binding; protein kinase activity; protein serine/threonine kinase activity

Biological Process: cell division; cell surface receptor linked signal transduction; Golgi organization and biogenesis; intermediate filament cytoskeleton organization and biogenesis; mitosis; peptidyl-serine phosphorylation; phagocytosis; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; proteasomal ubiquitin-dependent protein catabolic process; protein amino acid phosphorylation; regulation of cell shape; signal transduction; Wnt receptor signaling pathway
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Research Articles on CSNK1A1

1. characterization of frequency and potential clinical impact of CSNK1A1 mutations in myelodysplastic syndrome(MDS) and acute myeloid leukemia following MDS in a large cohort of patients

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-CSNK1A1 antibody

 Products by Pathway  Pathway Diagram
 AMER1 Mutants Destabilize The Destruction Complex Pathway antibodies  AMER1 Mutants Destabilize The Destruction Complex Pathway Diagram
 APC Truncation Mutants Have Impaired AXIN Binding Pathway antibodies  APC Truncation Mutants Have Impaired AXIN Binding Pathway Diagram
 AXIN Missense Mutants Destabilize The Destruction Complex Pathway antibodies  AXIN Missense Mutants Destabilize The Destruction Complex Pathway Diagram
 AXIN Mutants Destabilize The Destruction Complex, Activating WNT Signaling Pathway antibodies  AXIN Mutants Destabilize The Destruction Complex, Activating WNT Signaling Pathway Diagram
 Activation Of SMO Pathway antibodies  Activation Of SMO Pathway Diagram
 Beta-catenin Phosphorylation Cascade Pathway antibodies  Beta-catenin Phosphorylation Cascade Pathway Diagram
 Canonical Wnt Signaling Pathway antibodies  Canonical Wnt Signaling Pathway Diagram
 Degradation Of GLI2 By The Proteasome Pathway antibodies  Degradation Of GLI2 By The Proteasome Pathway Diagram
 Degradation Of Beta-catenin By The Destruction Complex Pathway antibodies  Degradation Of Beta-catenin By The Destruction Complex Pathway Diagram
 Disassembly Of The Destruction Complex And Recruitment Of AXIN To The Membrane Pathway antibodies  Disassembly Of The Destruction Complex And Recruitment Of AXIN To The Membrane Pathway Diagram

Diseases associated with anti-CSNK1A1 antibody

 Disease Name  Pubmed Publications
 Cell Transformation, Neoplastic Antibodies  >2 publications with CSNK1A1 and Cell Transformation, Neoplastic
 Prostatic Neoplasms Antibodies  >1 publications with CSNK1A1 and Prostatic Neoplasms
 Disease Models, Animal Antibodies  >1 publications with CSNK1A1 and Disease Models, Animal
 Prostatic Diseases Antibodies  >1 publications with CSNK1A1 and Prostatic Diseases
 Nervous System Diseases Antibodies  >1 publications with CSNK1A1 and Nervous System Diseases
 Cognition Disorders Antibodies  >1 publications with CSNK1A1 and Cognition Disorders
 Anemia Antibodies  >1 publications with CSNK1A1 and Anemia
 Inflammation Antibodies  >1 publications with CSNK1A1 and Inflammation
 Hyperplasia Antibodies  >1 publications with CSNK1A1 and Hyperplasia
 Leukemia-Lymphoma, Adult T-Cell Antibodies  >1 publications with CSNK1A1 and Leukemia-Lymphoma, Adult T-Cell

Organs/Tissues associated with anti-CSNK1A1 antibody

 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >6 publications with CSNK1A1 and Lung
 Blood Antibodies  >4 publications with CSNK1A1 and Blood
 Bone Antibodies  >3 publications with CSNK1A1 and Bone
 Bone Marrow Antibodies  >2 publications with CSNK1A1 and Bone Marrow
 Brain Antibodies  >2 publications with CSNK1A1 and Brain
 Lymph Node Antibodies  >1 publications with CSNK1A1 and Lymph Node
 Intestine Antibodies  >1 publications with CSNK1A1 and Intestine
 Skin Antibodies  >1 publications with CSNK1A1 and Skin
 Muscle Antibodies  >1 publications with CSNK1A1 and Muscle
 Prostate Antibodies  >1 publications with CSNK1A1 and Prostate
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