Pigeon CAPZbeta ELISA Kit – Cat# MBS076829

Capping Protein Muscle Z Line Beta (CAPZbeta) ELISA Kit for Pigeon

Name: Pigeon CAPZbeta ELISA Kit; Capping Protein Muscle Z Line Beta; MyBioSource
Brand: MyBioSource
SKU: MBS076829
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS076829

Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only! This kit is intended to be used for determination the level of CAPZB (hereafter termed "analyte") in undiluted original Pigeon body fluids, tissue homogenates, secretions… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

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Product Overview

Online Datasheet in PDF

Product Name

Capping Protein Muscle Z Line Beta (CAPZbeta), ELISA Kit

Full Product Name

Pigeon Capping Protein Muscle Z Line Beta ELISA Kit

Product Gene Name

CAPZbeta elisa kit

Species Reactivity

Pigeon

Assay Type

Sandwich (Quantitative)

Detection Range

0.25ng/ml-8ng/ml.

Sensitivity

0.1ng/ml.

Specificity

No significant cross-reactivity or interference between this analyte and analogues is observed.

Preparation and Storage

Store all reagents at 2-8 degree C

Inter-assay Precision

Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

Intra-assay Precision

Intra-assay CV (%) is less than 15%.

Molecular Weight

31,364 Da

3D Structure

ModBase 3D Structure for P14315

Other Notes

Small volumes of CAPZbeta elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CAPZbeta purchase

MBS076829 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Capping Protein Muscle Z Line Beta (CAPZbeta) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing CAPZbeta. The ELISA analytical biochemical technique of the MBS076829 kit is based on CAPZbeta antibody-CAPZbeta antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CAPZbeta antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CAPZbeta. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for CAPZbeta. It may not necessarily be applicable to this product.

NCBI GI #

291084676

NCBI GeneID

396418

NCBI Accession #

NP_001167000.1

UniProt Primary Accession #

P14315

UniProt Related Accession #

P14315

GenBank Nucleotide #

NM_001173529.1

NCBI Official Full Name

capping protein (actin filament) muscle Z-line, beta isoform 2

NCBI Official Synonym Full Names

capping protein (actin filament) muscle Z-line, beta

NCBI Official Symbol

CAPZB

UniProt Protein Name

F-actin-capping protein subunit beta isoforms 1 and 2

UniProt Synonym Protein Names

Beta-actinin subunit II; CapZ 36/32; CapZ B1 and B2

UniProt Gene Name

CAPZB

UniProt Entry Name

CAPZB_CHICK

NCBI Protein Information

capping protein (actin filament) muscle Z-line, beta; capping protein (actin filament) muscle Z-line, beta; capZ 36/32; capZ B1 and B2; beta-actinin subunit II; F-actin-capping protein subunit beta; actin-capping protein Z (cap-Z) beta subunit

UniProt Comments for CAPZbeta

Function: F-actin-capping proteins bind in a Ca2+-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. May play a role in the regulation of cell morphology and cytoskeletal organization.

Subunit structure: Heterodimer of an alpha and a beta subunit. Component of the WASH complex

By similarity. Isoform 2 also is a component of dynactin complex from brain, which contains the actin-related protein ARP1. Ref.2

Subcellular location: Isoform 1: Cytoplasm › myofibril › sarcomere › Z line. Note: In cardiac muscle, isoform 1 is located at Z-disks of sarcomeres. Ref.2Isoform 2: Cytoplasm › myofibril › sarcomere › I band. Cytoplasm › cytoskeleton

By similarity. Note: In cardiac muscle, isoform 2 is located at sarcomere intercalated disks. Ref.2

Tissue specificity: Isoform 1 is detected in pectoral muscle, cardiac muscle and gizzard. Isoform 2 is detected in brain and liver (at protein level). Isoform 2 is the predominant isoform ofnonmuscle tissues and isoform 1 is the predominant isoform ofmuscle tissues. Ref.2

Sequence similarities: Belongs to the F-actin-capping protein beta subunit family.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with CAPZbeta elisa kit

Reference Product	PubMed Publications
ARPC2 elisa kit	>1 publications with CAPZbeta and ARPC2
CAPZA2 elisa kit	>1 publications with CAPZbeta and CAPZA2
CAPZA1 elisa kit	>1 publications with CAPZbeta and CAPZA1

Diseases associated with CAPZbeta elisa kit

Disease Name	Pubmed Publications
Inflammation Antibodies	>2 publications with CAPZbeta and Inflammation
Immune System Diseases Antibodies	>1 publications with CAPZbeta and Immune System Diseases
Atrophy Antibodies	>1 publications with CAPZbeta and Atrophy
Atherosclerosis Antibodies	>1 publications with CAPZbeta and Atherosclerosis
Nervous System Diseases Antibodies	>1 publications with CAPZbeta and Nervous System Diseases
Carcinoma Antibodies	>1 publications with CAPZbeta and Carcinoma

Organs/Tissues associated with CAPZbeta elisa kit

Organ/Tissue Name	Pubmed Publications
Muscle Antibodies	>6 publications with CAPZbeta and Muscle
Blood Antibodies	>4 publications with CAPZbeta and Blood
Other Antibodies	>4 publications with CAPZbeta and Other
Heart Antibodies	>1 publications with CAPZbeta and Heart
Head Antibodies	>1 publications with CAPZbeta and Head