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CYP4F3 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS768405

MBS768405 is an antibody targeting CYP4F3. Also known as CYP4F3 Rabbit Polyclonal. Reactive in Human. Host: Rabbit. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
CYP4F3, Polyclonal Antibody
Full Product Name
CYP4F3 Rabbit Polyclonal
Product Gene Name
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid
Purity/Purification
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Preparation and Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)
Molecular Weight
59,739 Da
OMIM
601270
Immunogen
Cytochrome P450, family 4, subfamily F, polypeptide 3
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Applications Tested/Suitable for anti-CYP4F3 antibody
ELISA (EIA), Western Blot (WB)

Western Blot (WB) of anti-CYP4F3 antibody

HL-60 cells were subjected to SDS PAGE followed by western blot with MBS768405 (CYP4F3 Antibody) at dilution of 1:300
Rabbit Anti-CYP4F3 Polyclonal Antibody – Cat# MBS768405

Other Notes

Small volumes of anti-CYP4F3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CYP4F3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
CYP4F3 protein
NCBI Official Synonym Full Names
cytochrome P450 family 4 subfamily F member 3
NCBI Official Symbol
CYP4F3
NCBI Official Synonym Symbols
CPF3; CYP4F; LTB4H
UniProt Protein Name
Docosahexaenoic acid omega-hydroxylase CYP4F3
UniProt Synonym Protein Names
20-hydroxyeicosatetraenoic acid synthase
UniProt Gene Name
CYP4F3
UniProt Synonym Gene Names
LTB4H; 20-HETE synthase
UniProt Entry Name
CP4F3_HUMAN
NCBI Protein Information
docosahexaenoic acid omega-hydroxylase CYP4F3

NCBI Summary for CYP4F3

This gene, CYP4F3, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. The enzyme starts the process of inactivating and degrading leukotriene B4, a potent mediator of inflammation. This gene is part of a cluster of cytochrome P450 genes on chromosome 19. Another member of this family, CYP4F8, is approximately 18 kb away. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]
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UniProt Comments for CYP4F3

CYP4F3: Cytochromes P450 are a group of heme-thiolate monooxygenases. This enzyme requires molecular oxygen and NADPH for the omega-hydroxylation of LTB4, a potent chemoattractant for polymorphonuclear leukocytes. Belongs to the cytochrome P450 family.

Protein type: Membrane protein, integral; EC 1.14.13.30; Oxidoreductase; Lipid Metabolism - arachidonic acid

Chromosomal Location of Human Ortholog: 19p13.2

Cellular Component: endoplasmic reticulum membrane; integral to membrane

Molecular Function: heme binding; iron ion binding; leukotriene-B4 20-monooxygenase activity; monooxygenase activity; oxygen binding

Biological Process: icosanoid metabolic process; leukotriene metabolic process
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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