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Cytokeratin 4 (KRT4) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS768446

MBS768446 is an antibody targeting KRT4. Also known as Cytokeratin 4 Rabbit Polyclonal. Reactive in Human, Mouse, Rat. Host: Rabbit. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Cytokeratin 4 (KRT4), Polyclonal Antibody
Full Product Name
Cytokeratin 4 Rabbit Polyclonal
Product Gene Name
anti-KRT4 antibody
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid
Purity/Purification
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Preparation and Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)
Molecular Weight
57,285 Da
OMIM
123940
3D Structure
ModBase 3D Structure for P19013
Immunogen
Keratin 4
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Applications Tested/Suitable for anti-KRT4 antibody
ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB)

Immunohistochemistry (IHC) of anti-KRT4 antibody

Immunohistochemistry of paraffin-embedded human cervix using MBS768446 (KRT4 antibody) at dilution of 1:100
Rabbit Anti-KRT4 Polyclonal Antibody – Cat# MBS768446

Western Blot (WB) of anti-KRT4 antibody

A431 cells were subjected to SDS PAGE followed by western blot with MBS768446 (KRT4 Antibody) at dilution of 1:600
Rabbit Anti-KRT4 Polyclonal Antibody, Western Blot (WB) – Cat# MBS768446

Other Notes

Small volumes of anti-KRT4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for KRT4. It may not necessarily be applicable to this product.

NCBI GI #
34073
NCBI Accession #
CAA30534.1
UniProt Primary Accession #
P19013
UniProt Secondary Accession #
Q6GTR8; Q96LA7; Q9BTL1; F8VS64
NCBI Official Full Name
cytokeratin 4 (408 AA), partial
UniProt Protein Name
Keratin, type II cytoskeletal 4
UniProt Synonym Protein Names
Cytokeratin-4; CK-4; Keratin-4; K4; Type-II keratin Kb4
Protein Family
Keratin
UniProt Gene Name
KRT4
UniProt Synonym Gene Names
CYK4; CK-4; K4
UniProt Entry Name
K2C4_HUMAN

UniProt Comments for KRT4

K4: Heterotetramer of two type I and two type II keratins. Keratin-4 is generally associated with keratin-13. Detected in the suprabasal layer of the stratified epithelium of the esophagus, exocervix, vagina, mouth and lingual mucosa, and in cells and cell clusters in the mucosa and serous gland ducts of the esophageal submucosa. Expressed widely in the exocervix and esophageal epithelium, with lowest levels detected in the basal cell layer. Belongs to the intermediate filament family.

Protein type: Cytoskeletal

Chromosomal Location of Human Ortholog: 12q13.13

Cellular Component: cell surface; intermediate filament; intermediate filament cytoskeleton; keratin filament; nucleus

Molecular Function: protein binding; structural molecule activity

Biological Process: cytoskeleton organization and biogenesis; epithelial cell differentiation; negative regulation of epithelial cell proliferation

Disease: White Sponge Nevus 1
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-KRT4 antibody

 Organ/Tissue Name  Pubmed Publications
 Skin Antibodies  >13 publications with KRT4 and Skin
 Mouth Antibodies  >6 publications with KRT4 and Mouth
 Lung Antibodies  >2 publications with KRT4 and Lung
 Eye Antibodies  >2 publications with KRT4 and Eye
 Embryonic Tissue Antibodies  >2 publications with KRT4 and Embryonic Tissue
 Esophagus Antibodies  >2 publications with KRT4 and Esophagus
 Muscle Antibodies  >1 publications with KRT4 and Muscle
 Uncharacterized Tissue Antibodies  >1 publications with KRT4 and Uncharacterized Tissue
 Heart Antibodies  >1 publications with KRT4 and Heart
 Brain Antibodies  >1 publications with KRT4 and Brain
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