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DDX17 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS768528

MBS768528 is an antibody targeting DDX17. Also known as DDX17 Rabbit Polyclonal. Reactive in Human, Mouse, Rat. Host: Rabbit. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
DDX17, Polyclonal Antibody
Full Product Name
DDX17 Rabbit Polyclonal
Product Gene Name
anti-DDX17 antibody
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid
Purity/Purification
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Preparation and Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)
Molecular Weight
72,557 Da
OMIM
608469
3D Structure
ModBase 3D Structure for Q92841
Immunogen
DEAD (Asp-Glu-Ala-Asp) box polypeptide 17
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Applications Tested/Suitable for anti-DDX17 antibody
ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF), Western Blot (WB), Immunoprecipitation (IP)

Immunohistochemistry (IHC) of anti-DDX17 antibody

Immunohistochemistry of paraffin-embedded human kidney using MBS768528 (DDX17 antibody) at dilution of 1:100
Rabbit Anti-DDX17 Polyclonal Antibody – Cat# MBS768528

Immunofluorescence (IF) of anti-DDX17 antibody

Immunofluorescent analysis of Hela cells, using DDX17 antibody MBS768528 at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red) .
Rabbit Anti-DDX17 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS768528

Immunoprecipitation (IP) of anti-DDX17 antibody

IP Result of anti-DDX17,P72 (IP: MBS768528, 4ug; Detection: MBS768528 1:1000) with mouse brain tissue lysate 3000ug.
Rabbit Anti-DDX17 Polyclonal Antibody, Immunoprecipitation (IP) – Cat# MBS768528

Western Blot (WB) of anti-DDX17 antibody

HEK-293 tissue were subjected to SDS PAGE followed by western blot with MBS768528 (DDX17 antibody) at dilution of 1:1000
Rabbit Anti-DDX17 Polyclonal Antibody, Western Blot (WB) – Cat# MBS768528

Other Notes

Small volumes of anti-DDX17 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for DDX17. It may not necessarily be applicable to this product.

NCBI GI #
47678395
NCBI Accession #
CAG30318.1
UniProt Primary Accession #
Q92841
UniProt Secondary Accession #
Q69YT1; Q6ICD6; B1AHM0
NCBI Official Full Name
DDX17
UniProt Protein Name
Probable ATP-dependent RNA helicase DDX17
UniProt Synonym Protein Names
DEAD box protein 17; DEAD box protein p72; RNA-dependent helicase p72
Protein Family
Probable ATP-dependent RNA helicase
UniProt Gene Name
DDX17
UniProt Entry Name
DDX17_HUMAN

UniProt Comments for DDX17

DDX17: RNA-dependent ATPase activity. Involved in transcriptional regulation. Transcriptional coactivator for estrogen receptor ESR1. Increases ESR1 AF-1 domain-mediated transactivation. Synergizes with DDX5 and SRA1 RNA to activate MYOD1 transcriptional activity and probably involved in skeletal muscle differentiation. Required for zinc-finger antiviral protein ZC3HAV1-mediated mRNA degradation. Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: RNA-binding; Nucleolus; Helicase; EC 3.6.4.13; Transcription, coactivator/corepressor; Nuclear receptor co-regulator; Spliceosome; RNA processing

Chromosomal Location of Human Ortholog: 22q13.1

Cellular Component: membrane; nucleolus; nucleoplasm; nucleus

Molecular Function: ATP binding; ATP-dependent RNA helicase activity; estrogen receptor binding; protein binding; RNA binding; RNA helicase activity; RNA-dependent ATPase activity; transcription coactivator activity

Biological Process: positive regulation of estrogen receptor signaling pathway; positive regulation of transcription from RNA polymerase II promoter; RNA processing; RNA secondary structure unwinding; transcription, DNA-dependent
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-DDX17 antibody

 Reference Product  PubMed Publications
 DHX9 antibody  >4 publications with DDX17 and DHX9
 DROSHA antibody  >3 publications with DDX17 and DROSHA
 TP53 antibody  >1 publications with DDX17 and TP53

Diseases associated with anti-DDX17 antibody

 Disease Name  Pubmed Publications
 Breast Neoplasms Antibodies  >5 publications with DDX17 and Breast Neoplasms
 Nervous System Diseases Antibodies  >3 publications with DDX17 and Nervous System Diseases
 Neoplasm Invasiveness Antibodies  >1 publications with DDX17 and Neoplasm Invasiveness
 Liver Neoplasms Antibodies  >1 publications with DDX17 and Liver Neoplasms
 Neurobehavioral Manifestations Antibodies  >1 publications with DDX17 and Neurobehavioral Manifestations
 Carcinoma, Hepatocellular Antibodies  >1 publications with DDX17 and Carcinoma, Hepatocellular
 Neoplasm Metastasis Antibodies  >1 publications with DDX17 and Neoplasm Metastasis
 Liver Diseases Antibodies  >1 publications with DDX17 and Liver Diseases
 Hemorrhage Antibodies  >1 publications with DDX17 and Hemorrhage
 Kidney Diseases Antibodies  >1 publications with DDX17 and Kidney Diseases

Organs/Tissues associated with anti-DDX17 antibody

 Organ/Tissue Name  Pubmed Publications
 Prostate Antibodies  >4 publications with DDX17 and Prostate
 Muscle Antibodies  >3 publications with DDX17 and Muscle
 Blood Antibodies  >2 publications with DDX17 and Blood
 Liver Antibodies  >2 publications with DDX17 and Liver
 Kidney Antibodies  >2 publications with DDX17 and Kidney
 Brain Antibodies  >2 publications with DDX17 and Brain
 Stomach Antibodies  >1 publications with DDX17 and Stomach
 Testis Antibodies  >1 publications with DDX17 and Testis
 Eye Antibodies  >1 publications with DDX17 and Eye
 Intestine Antibodies  >1 publications with DDX17 and Intestine
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