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Desmocollin 2 (DSC2) Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS768576

MBS768576 is an antibody targeting DSC2. Also known as Desmocollin 2 Mouse Monoclonal. Reactive in Human, Mouse. Host: Mouse. More details

$360 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Desmocollin 2 (DSC2), Monoclonal Antibody
Full Product Name
Desmocollin 2 Mouse Monoclonal
Product Gene Name
Product Synonym Names
ARVD11, Cadherin family member 2, CDHF2, desmocollin 2, Desmocollin 3, Desmosomal glycoprotein II, Desmosomal glycoprotein III, DG2, DGII/III, DSC2, DSC3
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
7D7
Host
Mouse
Species Reactivity
Human, Mouse
Form/Format
Liquid; PBS with 0.02% sodium azide and 50% glycerol pH 7.3,
Purity/Purification
>95% as determined by SDS-PAGE
Protein A+G purification
Preparation and Storage
Store at -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Molecular Weight
Observed MW: 110 kDa
OMIM
125645
Immunogen
Desmocollin 2
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Applications Tested/Suitable for anti-DSC2 antibody
ELISA (EIA), Western Blot (WB)
Application Notes for anti-DSC2 antibody
WB: 1:1000-1:4000

Western Blot (WB) of anti-DSC2 antibody

HEK-293 cells were subjected to SDS PAGE followed by western blot with MBS768576 (Desmocollin 2 antibody) at dilution of 1:2000
Mouse Anti-DSC2 Monoclonal Antibody – Cat# MBS768576

Other Notes

Small volumes of anti-DSC2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for DSC2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Related Accession #
NCBI Official Full Name
Desmocollin 2
NCBI Official Synonym Full Names
desmocollin 2
NCBI Official Symbol
DSC2
NCBI Official Synonym Symbols
DG2; DSC3; CDHF2; ARVD11; DGII/III
UniProt Protein Name
Desmocollin-2
UniProt Synonym Protein Names
Cadherin family member 2; Desmocollin-3; Desmosomal glycoprotein II; Desmosomal glycoprotein III
Protein Family
UniProt Gene Name
DSC2
UniProt Synonym Gene Names
CDHF2; DSC3
UniProt Entry Name
DSC2_HUMAN
NCBI Protein Information
desmocollin-2

NCBI Summary for DSC2

This gene encodes a member of the desmocollin protein subfamily. Desmocollins, along with desmogleins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmocollin family members on chromosome 18. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia-11, and reduced protein expression has been described in several types of cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015]
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UniProt Comments for DSC2

Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. May contribute to epidermal cell positioning (stratification) by mediating differential adhesiveness between cells that express different isoforms.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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