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DNAJB4 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS768682

MBS768682 is an antibody targeting DNAJB4. Also known as DNAJB4 Rabbit Polyclonal. Reactive in Human, Mouse, Rat. Host: Rabbit. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
DNAJB4, Polyclonal Antibody
Full Product Name
DNAJB4 Rabbit Polyclonal
Product Gene Name
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid
Purity/Purification
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Preparation and Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)
Molecular Weight
37,807 Da
OMIM
611327
Immunogen
DnaJ (Hsp40) homolog, subfamily B, member 4
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Applications Tested/Suitable for anti-DNAJB4 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Immunohistochemistry (IHC) of anti-DNAJB4 antibody

Immunohistochemistry of paraffin-embedded human pancreas cancer using MBS768682 (DNAJB4 antibody) at dilution of 1:100
Rabbit Anti-DNAJB4 Polyclonal Antibody – Cat# MBS768682

Immunofluorescence (IF) of anti-DNAJB4 antibody

Immunofluorescent analysis of MCF-7 cells, using MBS768682 (DNAJB4 antibody) at 1:50 dilution and Rhodamine-labeled goat anti-rabbit IgG (red)
Rabbit Anti-DNAJB4 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS768682

Western Blot (WB) of anti-DNAJB4 antibody

HeLa cells were subjected to SDS PAGE followed by western blot with MBS768682 (DNAJB4 Antibody) at dilution of 1:2000
Rabbit Anti-DNAJB4 Polyclonal Antibody, Western Blot (WB) – Cat# MBS768682

Other Notes

Small volumes of anti-DNAJB4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for DNAJB4. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
dnaJ homolog subfamily B member 4 isoform d
NCBI Official Synonym Full Names
DnaJ heat shock protein family (Hsp40) member B4
NCBI Official Symbol
DNAJB4
NCBI Official Synonym Symbols
DjB4; HLJ1; DNAJW
UniProt Protein Name
DnaJ homolog subfamily B member 4
UniProt Synonym Protein Names
Heat shock 40 kDa protein 1 homolog; HSP40 homolog; Heat shock protein 40 homolog; Human liver DnaJ-like protein
UniProt Gene Name
DNAJB4
UniProt Synonym Gene Names
DNAJW; HLJ1; HSP40 homolog; Heat shock protein 40 homolog
UniProt Entry Name
DNJB4_HUMAN
NCBI Protein Information
dnaJ homolog subfamily B member 4

NCBI Summary for DNAJB4

The protein encoded by this gene is a molecular chaperone, tumor suppressor, and member of the heat shock protein-40 family. The encoded protein binds the cell adhesion protein E-cadherin and targets it to the plasma membrane. This protein also binds incorrectly folded E-cadherin and targets it for endoplasmic reticulum-associated degradation. This gene is a strong tumor suppressor for colorectal carcinoma, and downregulation of it may serve as a good biomarker for predicting patient outcomes. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015]
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UniProt Comments for DNAJB4

DNAJB4: Probable chaperone. Homodimer. The C-terminal section interacts with the C- terminal tail of OPRM1. Interacts also with SDIM1. By heat shock. Expressed in heart, pancreas and skeletal muscle, and to a lesser extent in brain, placenta and liver.

Protein type: Chaperone

Chromosomal Location of Human Ortholog: 1p31.1

Cellular Component: cytoplasm; cytosol; nucleoplasm; plasma membrane

Molecular Function: chaperone binding; protein binding; unfolded protein binding

Biological Process: protein folding; response to heat; response to unfolded protein
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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