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DRIM Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS768771

MBS768771 is an antibody targeting DRIM. Also known as DRIM Rabbit Polyclonal. Reactive in Human, Mouse, Rat. Host: Rabbit. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
DRIM, Polyclonal Antibody
Full Product Name
DRIM Rabbit Polyclonal
Product Gene Name
anti-DRIM antibody
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid
Purity/Purification
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Preparation and Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)
Molecular Weight
318,385 Da
OMIM
612822
3D Structure
ModBase 3D Structure for O75691
Immunogen
UTP20, small subunit (SSU) processome component, homolog (yeast)
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Applications Tested/Suitable for anti-DRIM antibody
ELISA (EIA), Western Blot (WB), Immunofluorescence (IF)

Western Blot (WB) of anti-DRIM antibody

HeLa cells were subjected to SDS PAGE followed by western blot with MBS768771 (DRIM antibody) at dilution of 1:1000
Rabbit Anti-DRIM Polyclonal Antibody – Cat# MBS768771

Other Notes

Small volumes of anti-DRIM antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for DRIM. It may not necessarily be applicable to this product.

NCBI GI #
3242214
NCBI GeneID
27340
NCBI Accession #
CAA07243.1
UniProt Primary Accession #
O75691
UniProt Secondary Accession #
Q9H3H4
UniProt Related Accession #
O75691
NCBI Official Full Name
DRIM protein
NCBI Official Synonym Full Names
UTP20, small subunit processome component
NCBI Official Symbol
UTP20
NCBI Official Synonym Symbols
DRIM; 1A6/DRIM
UniProt Protein Name
Small subunit processome component 20 homolog
UniProt Synonym Protein Names
Down-regulated in metastasis protein; Novel nucleolar protein 73; NNP73; Protein Key-1A6
UniProt Gene Name
UTP20
UniProt Synonym Gene Names
DRIM; NNP73
UniProt Entry Name
UTP20_HUMAN
NCBI Protein Information
small subunit processome component 20 homolog

NCBI Summary for DRIM

UTP20 is a component of the U3 small nucleolar RNA (snoRNA) (SNORD3A; MIM 180710) protein complex (U3 snoRNP) and is involved in 18S rRNA processing (Wang et al., 2007 [PubMed 17498821]).[supplied by OMIM, Jun 2009]

UniProt Comments for DRIM

DRIM: Involved in 18S pre-rRNA processing. Associates with U3 snoRNA. Belongs to the UTP20 family.

Protein type: Nucleolus; Translation

Chromosomal Location of Human Ortholog: 12q23

Cellular Component: cytoplasm; nucleolar preribosome, small subunit precursor; nucleolus; nucleoplasm; small subunit processome

Molecular Function: protein binding

Biological Process: endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA); maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); negative regulation of cell proliferation; rRNA processing
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Research Articles on DRIM

1. 1A6/DRIM activates Pol I transcription most likely by associating with both hALP and UBF and thereby affecting the acetylation of UBF

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-DRIM antibody

 Products by Pathway  Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 Major Pathway Of RRNA Processing In The Nucleolus antibodies  Major Pathway Of RRNA Processing In The Nucleolus Diagram
 RRNA Modification In The Nucleus Pathway antibodies  RRNA Modification In The Nucleus Pathway Diagram
 RRNA Processing Pathway antibodies  RRNA Processing Pathway Diagram

Diseases associated with anti-DRIM antibody

 Disease Name  Pubmed Publications
 Neoplasm Metastasis Antibodies  >2 publications with DRIM and Neoplasm Metastasis
 Cell Transformation, Neoplastic Antibodies  >1 publications with DRIM and Cell Transformation, Neoplastic

Organs/Tissues associated with anti-DRIM antibody

 Organ/Tissue Name  Pubmed Publications
 Nerve Antibodies  >1 publications with DRIM and Nerve
 Brain Antibodies  >1 publications with DRIM and Brain
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