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EFS Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS768894

MBS768894 is an antibody targeting EFS. Also known as EFS Rabbit Polyclonal. Reactive in Human, Mouse, Rat. Host: Rabbit. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
EFS, Polyclonal Antibody
Full Product Name
EFS Rabbit Polyclonal
Product Gene Name
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid
Purity/Purification
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Preparation and Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)
Molecular Weight
40,957 Da
OMIM
609906
Immunogen
Embryonal Fyn-associated substrate
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Applications Tested/Suitable for anti-EFS antibody
ELISA (EIA), Western Blot (WB), Immunofluorescence (IF)

Immunohistochemistry (IHC) of anti-EFS antibody

Immunohistochemistry of paraffin-embedded human spleen using MBS768894 (EFS antibody) at dilution of 1:100
Rabbit Anti-EFS Polyclonal Antibody – Cat# MBS768894

Immunofluorescence (IF) of anti-EFS antibody

Immunofluorescent analysis of HepG2 cells, using MBS768894 (EFS antibody) at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red) .
Rabbit Anti-EFS Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS768894

Western Blot (WB) of anti-EFS antibody

mouse thymus tissue were subjected to SDS PAGE followed by western blot with MBS768894 (EFS antibody) at dilution of 1:500
Rabbit Anti-EFS Polyclonal Antibody, Western Blot (WB) – Cat# MBS768894

Other Notes

Small volumes of anti-EFS antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for EFS. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
embryonal Fyn-associated substrate isoform 1
NCBI Official Synonym Full Names
embryonal Fyn-associated substrate
NCBI Official Symbol
EFS
NCBI Official Synonym Symbols
SIN; CAS3; EFS1; EFS2; HEFS; CASS3
UniProt Protein Name
Embryonal Fyn-associated substrate
UniProt Synonym Protein Names
Cas scaffolding protein family member 3
UniProt Gene Name
EFS
UniProt Synonym Gene Names
CASS3; hEFS
UniProt Entry Name
EFS_HUMAN
NCBI Protein Information
embryonal Fyn-associated substrate

NCBI Summary for EFS

The longest protein isoform encoded by this gene contains an SH3 domain, which is known to be important in intracellular signal transduction. The protein encoded by a similiar gene in mice was shown to bind to SH3 domains of protein-tyrosine kinases. The function of this gene is unknown. Three alternatively spliced variants encoding different isoforms have been described for this gene. [provided by RefSeq, Mar 2013]
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UniProt Comments for EFS

EFS: Docking protein which plays a central coordinating role for tyrosine-kinase-based signaling related to cell adhesion. May serve as an activator of SRC and a downstream effector. Interacts with the SH3 domain of FYN and with CRK, SRC, and YES. Belongs to the CAS family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Adaptor/scaffold; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 14q11.2

Cellular Component: cytoplasm

Molecular Function: protein binding; protein domain specific binding; SH3 domain binding

Biological Process: cell adhesion
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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