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EID1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS768913

MBS768913 is an antibody targeting EID1. Also known as EID1 Rabbit Polyclonal. Reactive in Human, Mouse. Host: Rabbit. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
EID1, Polyclonal Antibody
Full Product Name
EID1 Rabbit Polyclonal
Product Gene Name
anti-EID1 antibody
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Liquid
Purity/Purification
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Preparation and Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)
Molecular Weight
18,616 Da
OMIM
605894
Immunogen
EP300 interacting inhibitor of differentiation 1
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Applications Tested/Suitable for anti-EID1 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Immunohistochemistry (IHC) of anti-EID1 antibody

Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using MBS768913 (EID1 Antibody) at dilution of 1:50
Rabbit Anti-EID1 Polyclonal Antibody – Cat# MBS768913

Western Blot (WB) of anti-EID1 antibody

HepG2 cells were subjected to SDS PAGE followed by western blot with MBS768913 (EID1 antibody) at dilution of 1:300
Rabbit Anti-EID1 Polyclonal Antibody, Western Blot (WB) – Cat# MBS768913

Other Notes

Small volumes of anti-EID1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for EID1. It may not necessarily be applicable to this product.

NCBI GI #
7656938
NCBI GeneID
23741
NCBI Accession #
NP_055150.1
UniProt Secondary Accession #
Q8N7I4; Q9BZT9; B2RD11
UniProt Related Accession #
Q9Y6B2
GenBank Nucleotide #
NM_014335.2
NCBI Official Full Name
EP300-interacting inhibitor of differentiation 1
NCBI Official Synonym Full Names
EP300 interacting inhibitor of differentiation 1
NCBI Official Symbol
EID1
NCBI Official Synonym Symbols
CRI1; EID-1; RBP21; PTD014; C15orf3; PNAS-22; IRO45620
UniProt Protein Name
EP300-interacting inhibitor of differentiation 1
UniProt Synonym Protein Names
21 kDa pRb-associated protein; CREBBP/EP300 inhibitory protein 1; E1A-like inhibitor of differentiation 1; EID-1
Protein Family
EP300-interacting inhibitor of differentiation
UniProt Gene Name
EID1
UniProt Synonym Gene Names
EID-1
UniProt Entry Name
EID1_HUMAN
NCBI Protein Information
EP300-interacting inhibitor of differentiation 1

UniProt Comments for EID1

EID1: Interacts with RB1 and EP300 and acts as a repressor of MYOD1 transactivation. Inhibits EP300 and CBP histone acetyltransferase activity. May be involved in coupling cell cycle exit to the transcriptional activation of genes required for cellular differentiation. May act as a candidate coinhibitory factor for NR0B2 that can be directly linked to transcription inhibitory mechanisms. 2 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 15q21.1

Cellular Component: cytoplasm; nucleoplasm; nucleus

Molecular Function: histone acetyltransferase binding; histone acetyltransferase regulator activity; protein binding; transcription corepressor activity

Biological Process: cell cycle; cell differentiation; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; regulation of histone acetylation; transcription, DNA-dependent
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Research Articles on EID1

1. SCF(FBXO21) polyubiquitylates EID1 both in vitro and in vivo and is required for the efficient degradation of EID1 in both cycling and quiescent cells.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-EID1 antibody

 Reference Product  PubMed Publications
 MDM2 antibody  >6 publications with EID1 and MDM2
 EP300 antibody  >6 publications with EID1 and EP300
 EID2 antibody  >3 publications with EID1 and EID2
 CREBBP antibody  >2 publications with EID1 and CREBBP
 NR0B2 antibody  >2 publications with EID1 and NR0B2

Diseases associated with anti-EID1 antibody

 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >8 publications with EID1 and Carcinoma
 Cell Transformation, Neoplastic Antibodies  >3 publications with EID1 and Cell Transformation, Neoplastic
 Neurobehavioral Manifestations Antibodies  >2 publications with EID1 and Neurobehavioral Manifestations
 Lung Neoplasms Antibodies  >2 publications with EID1 and Lung Neoplasms
 Learning Disorders Antibodies  >1 publications with EID1 and Learning Disorders
 Memory Disorders Antibodies  >1 publications with EID1 and Memory Disorders
 Fibrosis Antibodies  >1 publications with EID1 and Fibrosis
 Weight Loss Antibodies  >1 publications with EID1 and Weight Loss
 Liver Diseases Antibodies  >1 publications with EID1 and Liver Diseases
 Cholestasis Antibodies  >1 publications with EID1 and Cholestasis

Organs/Tissues associated with anti-EID1 antibody

 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >7 publications with EID1 and Muscle
 Adipose Tissue Antibodies  >3 publications with EID1 and Adipose Tissue
 Testis Antibodies  >2 publications with EID1 and Testis
 Lung Antibodies  >2 publications with EID1 and Lung
 Lymph Antibodies  >2 publications with EID1 and Lymph
 Lymph Node Antibodies  >2 publications with EID1 and Lymph Node
 Connective Tissue Antibodies  >2 publications with EID1 and Connective Tissue
 Bone Antibodies  >1 publications with EID1 and Bone
 Kidney Antibodies  >1 publications with EID1 and Kidney
 Liver Antibodies  >1 publications with EID1 and Liver
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