Rabbit Anti-EIF3L Polyclonal Antibody – Cat# MBS768945

mouse brain tissue were subjected to SDS PAGE followed by western blot with MBS768945 (EIF3L Antibody) at dilution of 1:300

EIF3L Antibody – Rabbit Polyclonal

Name: EIF3L Antibody; Polyclonal; Rabbit; Human/Mouse/Rat-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS768945
Price: 330 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS768945

MBS768945 is an antibody targeting EIF3L. Also known as EIF3L Rabbit Polyclonal. Reactive in Human, Mouse, Rat. Host: Rabbit. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

EIF3L, Polyclonal Antibody

Full Product Name

EIF3L Rabbit Polyclonal

Product Gene Name

anti-EIF3L antibody

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Form/Format

Liquid

Purity/Purification

>=95% as determined by SDS-PAGE
Immunogen Affinity Purified

Preparation and Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Molecular Weight

61,014 Da

Immunogen

Eukaryotic translation initiation factor 3, subunit L

ISO Certification

Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Applications Tested/Suitable for anti-EIF3L antibody

ELISA (EIA), Western Blot (WB)

Other Notes

Small volumes of anti-EIF3L antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for EIF3L. It may not necessarily be applicable to this product.

NCBI GI #

339275831

NCBI GeneID

51386

NCBI Accession #

NP_001229852.1

UniProt Secondary Accession #

Q53HQ1; Q53HT4; Q5QTR1; Q5TI15; Q6ICD2; B2RDG6; B4DYB2; G8JLH4

UniProt Related Accession #

Q9Y262

GenBank Nucleotide #

NM_001242923.1

NCBI Official Full Name

eukaryotic translation initiation factor 3 subunit L isoform 2

NCBI Official Synonym Full Names

eukaryotic translation initiation factor 3 subunit L

NCBI Official Symbol

EIF3L

NCBI Official Synonym Symbols

EIF3EIP; EIF3S11; HSPC021; HSPC025; MSTP005; EIF3S6IP

UniProt Protein Name

Eukaryotic translation initiation factor 3 subunit L

UniProt Synonym Protein Names

Eukaryotic translation initiation factor 3 subunit 6-interacting protein

Protein Family

Eukaryotic translation initiation factor

UniProt Gene Name

EIF3L

UniProt Synonym Gene Names

eIF3l

UniProt Entry Name

EIF3L_HUMAN

NCBI Protein Information

eukaryotic translation initiation factor 3 subunit L

UniProt Comments for EIF3L

eIF3S6IP: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. Belongs to the eIF-3 subunit L family.

Protein type: Translation initiation; RNA-binding; Translation

Chromosomal Location of Human Ortholog: 22q

Cellular Component: cytosol; eukaryotic translation initiation factor 3 complex; fibrillar center; membrane; nucleoplasm

Molecular Function: protein binding; translation initiation factor activity

Biological Process: formation of translation preinitiation complex; regulation of translational initiation; translational initiation

Research Articles on EIF3L

1. These results indicate an interaction of human eIF3L with yellow fever virus NS5 and that eIF3L overexpression facilitates translation, which has potential implications for virus replication.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-EIF3L antibody

Reference Product	PubMed Publications
EIF3E antibody	>8 publications with EIF3L and EIF3E
EIF3H antibody	>3 publications with EIF3L and EIF3H
EIF3K antibody	>3 publications with EIF3L and EIF3K
EIF3A antibody	>2 publications with EIF3L and EIF3A
EIF3C antibody	>2 publications with EIF3L and EIF3C
EIF3F antibody	>2 publications with EIF3L and EIF3F
EIF3I antibody	>2 publications with EIF3L and EIF3I
EIF3G antibody	>1 publications with EIF3L and EIF3G
EIF3D antibody	>1 publications with EIF3L and EIF3D
EIF3M antibody	>1 publications with EIF3L and EIF3M

Pathways associated with anti-EIF3L antibody

Products by Pathway	Pathway Diagram
Activation Of The MRNA Upon Binding Of The Cap-binding Complex And EIFs, And Subsequent Binding To 43S Pathway antibodies	Activation Of The MRNA Upon Binding Of The Cap-binding Complex And EIFs, And Subsequent Binding To 43S Pathway Diagram
Cap-dependent Translation Initiation Pathway antibodies	Cap-dependent Translation Initiation Pathway Diagram
Eukaryotic Translation Initiation Pathway antibodies	Eukaryotic Translation Initiation Pathway Diagram
Formation Of A Pool Of Free 40S Subunits Pathway antibodies	Formation Of A Pool Of Free 40S Subunits Pathway Diagram
Formation Of The Ternary Complex, And Subsequently, The 43S Complex Pathway antibodies	Formation Of The Ternary Complex, And Subsequently, The 43S Complex Pathway Diagram
GTP Hydrolysis And Joining Of The 60S Ribosomal Subunit Pathway antibodies	GTP Hydrolysis And Joining Of The 60S Ribosomal Subunit Pathway Diagram
Gene Expression Pathway antibodies	Gene Expression Pathway Diagram
L13a-mediated Translational Silencing Of Ceruloplasmin Expression Pathway antibodies	L13a-mediated Translational Silencing Of Ceruloplasmin Expression Pathway Diagram
Metabolism Of Proteins Pathway antibodies	Metabolism Of Proteins Pathway Diagram
Ribosomal Scanning And Start Codon Recognition Pathway antibodies	Ribosomal Scanning And Start Codon Recognition Pathway Diagram

Diseases associated with anti-EIF3L antibody

Disease Name	Pubmed Publications
Carcinoma Antibodies	>1 publications with EIF3L and Carcinoma
Cell Transformation, Neoplastic Antibodies	>1 publications with EIF3L and Cell Transformation, Neoplastic
Hepatitis Antibodies	>1 publications with EIF3L and Hepatitis

Organs/Tissues associated with anti-EIF3L antibody

Organ/Tissue Name	Pubmed Publications
Heart Antibodies	>1 publications with EIF3L and Heart
Blood Antibodies	>1 publications with EIF3L and Blood
Lung Antibodies	>1 publications with EIF3L and Lung