Mouse Anti-ENTPD1 Monoclonal Antibody – Cat# MBS769013

Jurkat cells were subjected to SDS PAGE followed by western blot with MBS769013 (ENTPD1 Antibody) at dilution of 1:500

ENTPD1 Antibody – Mouse Monoclonal

Name: ENTPD1 Antibody; Monoclonal; Mouse; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS769013
Price: 380 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS769013

MBS769013 is an antibody targeting ENTPD1. Also known as ENTPD1 Mouse Monoclonal. Reactive in Human. Host: Mouse. More details

$380 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

ENTPD1, Monoclonal Antibody

Full Product Name

ENTPD1 Mouse Monoclonal

Product Gene Name

anti-ENTPD1 antibody

Clonality

Monoclonal

Isotype

IgG1

Host

Mouse

Species Reactivity

Human

Form/Format

Liquid

Purity/Purification

>=95% as determined by SDS-PAGE
Protein A+G purification

Preparation and Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Molecular Weight

59,325 Da

OMIM

601752

Immunogen

Ectonucleoside triphosphate diphosphohydrolase 1

ISO Certification

Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Applications Tested/Suitable for anti-ENTPD1 antibody

ELISA (EIA), Western Blot (WB), Immunofluorescence (IF)

Other Notes

Small volumes of anti-ENTPD1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ENTPD1. It may not necessarily be applicable to this product.

NCBI GI #

1004170670

NCBI GeneID

953

NCBI Accession #

NP_001307845.1

UniProt Secondary Accession #

Q5T561; Q5T562; Q86VV3; Q9UQQ9; Q9Y3Q9; A9Z1X8; B4DWB9; B4E1X1; B7Z599; G3XAF6

UniProt Related Accession #

P49961

GenBank Nucleotide #

NM_001320916.1

NCBI Official Full Name

ectonucleoside triphosphate diphosphohydrolase 1 isoform 7

NCBI Official Synonym Full Names

ectonucleoside triphosphate diphosphohydrolase 1

NCBI Official Symbol

ENTPD1

NCBI Official Synonym Symbols

CD39; SPG64; ATPDase; NTPDase-1

UniProt Protein Name

Ectonucleoside triphosphate diphosphohydrolase 1

UniProt Synonym Protein Names

Ecto-ATP diphosphohydrolase 1; Ecto-ATPDase 1; Ecto-ATPase 1; Ecto-apyrase; Lymphoid cell activation antigen; CD_antigen: CD39

Protein Family

Ectonucleoside triphosphate diphosphohydrolase

UniProt Gene Name

ENTPD1

UniProt Synonym Gene Names

CD39; NTPDase 1; Ecto-ATPDase 1; Ecto-ATPase 1

UniProt Entry Name

ENTP1_HUMAN

NCBI Protein Information

ectonucleoside triphosphate diphosphohydrolase 1

NCBI Summary for ENTPD1

The protein encoded by this gene is a plasma membrane protein that hydrolyzes extracellular ATP and ADP to AMP. Inhibition of this protein's activity may confer anticancer benefits. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2015]

UniProt Comments for ENTPD1

ENTPD1: an ectonucleotidase that, like CD73, hydrolyzes immunostimulatory ATP, and ADP, to immunosuppressive AMP. May inhibit host immune responses against cancer. Expressed at high levels in malignant epithelial cells of human rectal adenocarcinoma. A prognostic marker of chronic lymphocytic leukemia that may identify patients with an unfavorable clinical outcome. Synergizes with CD161 to modulate Th17 responses in Crohn's disease. It may hydrolyze ATP and other nucleotides in the nervous system to regulate purinergic neurotransmission in the nervous system. May be implicated in inhibiting platelet aggregation by hydrolyzing platelet-activating ADP to AMP. Hydrolyzes ATP and ADP equally well. Belongs to the GDA1/CD39 NTPase family. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.6.1.5; Extracellular matrix; Hydrolase; Membrane protein, integral; Membrane protein, multi-pass; Nucleotide Metabolism - purine; Nucleotide Metabolism - pyrimidine

Chromosomal Location of Human Ortholog: 10q24

Cellular Component: integral to plasma membrane; membrane

Molecular Function: protein binding

Biological Process: blood coagulation

Disease: Spastic Paraplegia 64, Autosomal Recessive

Research Articles on ENTPD1

1. We suggest modulation of human Th17 responsiveness by CD39 and CD161 and describe novel molecular mechanisms integrating elements of both extracellular nucleotide and sphingolipid homeostasis--{REVIEW}

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-ENTPD1 antibody

Products by Pathway	Pathway Diagram
Epstein-Barr Virus Infection Pathway antibodies	Epstein-Barr Virus Infection Pathway Diagram
Epstein-Barr Virus Infection Pathway antibodies	Epstein-Barr Virus Infection Pathway Diagram
Purine Metabolism Pathway antibodies	Purine Metabolism Pathway Diagram
Purine Metabolism Pathway antibodies	Purine Metabolism Pathway Diagram
Pyrimidine Metabolism Pathway antibodies	Pyrimidine Metabolism Pathway Diagram
Pyrimidine Metabolism Pathway antibodies	Pyrimidine Metabolism Pathway Diagram
UTP And CTP Dephosphorylation I Pathway antibodies	UTP And CTP Dephosphorylation I Pathway Diagram
UTP And CTP Dephosphorylation II Pathway antibodies	UTP And CTP Dephosphorylation II Pathway Diagram
UTP And CTP Dephosphorylation II Pathway antibodies	UTP And CTP Dephosphorylation II Pathway Diagram

Diseases associated with anti-ENTPD1 antibody

Disease Name	Pubmed Publications
Inflammation Antibodies	>16 publications with ENTPD1 and Inflammation
Disease Models, Animal Antibodies	>9 publications with ENTPD1 and Disease Models, Animal
Neoplasms, Experimental Antibodies	>6 publications with ENTPD1 and Neoplasms, Experimental
Necrosis Antibodies	>6 publications with ENTPD1 and Necrosis
Death Antibodies	>4 publications with ENTPD1 and Death
Hypertension Antibodies	>3 publications with ENTPD1 and Hypertension
Liver Diseases Antibodies	>3 publications with ENTPD1 and Liver Diseases
Lung Diseases Antibodies	>3 publications with ENTPD1 and Lung Diseases
Kidney Diseases Antibodies	>3 publications with ENTPD1 and Kidney Diseases
Cell Transformation, Neoplastic Antibodies	>2 publications with ENTPD1 and Cell Transformation, Neoplastic

Organs/Tissues associated with anti-ENTPD1 antibody

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>25 publications with ENTPD1 and Blood
Muscle Antibodies	>10 publications with ENTPD1 and Muscle
Liver Antibodies	>9 publications with ENTPD1 and Liver
Heart Antibodies	>5 publications with ENTPD1 and Heart
Kidney Antibodies	>4 publications with ENTPD1 and Kidney
Lung Antibodies	>4 publications with ENTPD1 and Lung
Pancreas Antibodies	>3 publications with ENTPD1 and Pancreas
Skin Antibodies	>3 publications with ENTPD1 and Skin
Bone Marrow Antibodies	>3 publications with ENTPD1 and Bone Marrow
Bone Antibodies	>3 publications with ENTPD1 and Bone