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FBXL14 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS769265

MBS769265 is an antibody targeting FBXL14. Also known as FBXL14 Rabbit Polyclonal. Reactive in Human, Mouse, Rat. Host: Rabbit. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
FBXL14, Polyclonal Antibody
Full Product Name
FBXL14 Rabbit Polyclonal
Product Gene Name
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid
Purity/Purification
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Preparation and Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)
Molecular Weight
45,886 Da
OMIM
609081
Immunogen
F-box and leucine-rich repeat protein 14
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Applications Tested/Suitable for anti-FBXL14 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

Immunohistochemistry (IHC) of anti-FBXL14 antibody

Immunohistochemistry of paraffin-embedded human liver using MBS769265 (FBXL14 antibody) at dilution of 1:50
Rabbit Anti-FBXL14 Polyclonal Antibody – Cat# MBS769265

Western Blot (WB) of anti-FBXL14 antibody

HepG2 cells were subjected to SDS PAGE followed by western blot with MBS769265 (FBXL14 antibody) at dilution of 1:800
Rabbit Anti-FBXL14 Polyclonal Antibody, Western Blot (WB) – Cat# MBS769265

Other Notes

Small volumes of anti-FBXL14 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for FBXL14. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
F-box/LRR-repeat protein 14
NCBI Official Synonym Full Names
F-box and leucine rich repeat protein 14
NCBI Official Symbol
FBXL14
NCBI Official Synonym Symbols
Fbl14
UniProt Protein Name
F-box/LRR-repeat protein 14
UniProt Synonym Protein Names
F-box and leucine-rich repeat protein 14
UniProt Gene Name
FBXL14
UniProt Synonym Gene Names
FBL14
UniProt Entry Name
FXL14_HUMAN
NCBI Protein Information
F-box/LRR-repeat protein 14

NCBI Summary for FBXL14

Members of the F-box protein family, such as FBXL14, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008]
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UniProt Comments for FBXL14

FBXL14: Substrate-recognition component of some SCF (SKP1-CUL1- F-box protein)-type E3 ubiquitin-protein ligase complexes. The SCF(FBXL14) complex acts by mediating ubiquitination and subsequent degradation of SNAI1.

Chromosomal Location of Human Ortholog: 12p13.33

Cellular Component: cytoplasm; Golgi apparatus; nucleoplasm

Molecular Function: protein binding; ubiquitin-protein ligase activity

Biological Process: protein ubiquitination during ubiquitin-dependent protein catabolic process
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-FBXL14 antibody

Organs/Tissues associated with anti-FBXL14 antibody

 Organ/Tissue Name  Pubmed Publications
 Nerve Antibodies  >1 publications with FBXL14 and Nerve
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