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FHL3 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS769344

MBS769344 is an antibody targeting FHL3. Also known as FHL3 Rabbit Polyclonal. Reactive in Human, Mouse, Rat. Host: Rabbit. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
FHL3, Polyclonal Antibody
Full Product Name
FHL3 Rabbit Polyclonal
Product Gene Name
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid
Purity/Purification
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Preparation and Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)
Molecular Weight
31,192 Da
OMIM
602790
Immunogen
Four and a half LIM domains 3
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Applications Tested/Suitable for anti-FHL3 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Immunohistochemistry (IHC) of anti-FHL3 antibody

Immunohistochemistry of paraffin-embedded human ovary tumor using MBS769344 (FHL3 antibody) at dilution of 1:50
Rabbit Anti-FHL3 Polyclonal Antibody – Cat# MBS769344

Western Blot (WB) of anti-FHL3 antibody

K-562 cells were subjected to SDS PAGE followed by western blot with MBS769344 (FHL3 antibody) at dilution of 1:500
Rabbit Anti-FHL3 Polyclonal Antibody, Western Blot (WB) – Cat# MBS769344

Other Notes

Small volumes of anti-FHL3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for FHL3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
four and a half LIM domains protein 3 isoform 1
NCBI Official Synonym Full Names
four and a half LIM domains 3
NCBI Official Symbol
FHL3
NCBI Official Synonym Symbols
SLIM2
UniProt Protein Name
Four and a half LIM domains protein 3
UniProt Synonym Protein Names
Skeletal muscle LIM-protein 2; SLIM-2
UniProt Gene Name
FHL3
UniProt Synonym Gene Names
SLIM2; FHL-3; SLIM-2
UniProt Entry Name
FHL3_HUMAN
NCBI Protein Information
four and a half LIM domains protein 3

NCBI Summary for FHL3

The protein encoded by this gene is a member of a family of proteins containing a four-and-a-half LIM domain, which is a highly conserved double zinc finger motif. The encoded protein has been shown to interact with the cancer developmental regulators SMAD2, SMAD3, and SMAD4, the skeletal muscle myogenesis protein MyoD, and the high-affinity IgE beta chain regulator MZF-1. This protein may be involved in tumor suppression, repression of MyoD expression, and repression of IgE receptor expression. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
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UniProt Comments for FHL3

FHL3:

Protein type: Actin-binding; Contractile

Chromosomal Location of Human Ortholog: 1p34

Cellular Component: focal adhesion; nucleus; stress fiber; Z disc

Molecular Function: actin binding; protein binding; zinc ion binding

Biological Process: actin cytoskeleton organization and biogenesis; muscle development
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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