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GPM6A Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS769816

MBS769816 is an antibody targeting GPM6A. Also known as GPM6A Rabbit Polyclonal. Reactive in Human, Mouse, Rat. Host: Rabbit. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
GPM6A, Polyclonal Antibody
Full Product Name
GPM6A Rabbit Polyclonal
Product Gene Name
anti-GPM6A antibody
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid
Purity/Purification
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Preparation and Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)
Molecular Weight
29,905 Da
OMIM
601275
Immunogen
Glycoprotein M6A
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Applications Tested/Suitable for anti-GPM6A antibody
ELISA (EIA), Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC)

Immunohistochemistry (IHC) of anti-GPM6A antibody

Immunohistochemistry of paraffin-embedded mouse stomach using MBS769816 (GPM6A antibody) at dilution of 1:50
Rabbit Anti-GPM6A Polyclonal Antibody – Cat# MBS769816

Western Blot (WB) of anti-GPM6A antibody

mouse retina tissue were subjected to SDS PAGE followed by western blot with MBS769816 (GPM6A antibody) at dilution of 1:1000
Rabbit Anti-GPM6A Polyclonal Antibody, Western Blot (WB) – Cat# MBS769816

Other Notes

Small volumes of anti-GPM6A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for GPM6A. It may not necessarily be applicable to this product.

NCBI GI #
71296879
NCBI GeneID
2823
NCBI Accession #
AAH37853.1
UniProt Secondary Accession #
Q92602; B7Z642; E9PHI5
UniProt Related Accession #
P51674
NCBI Official Full Name
GPM6A protein
NCBI Official Synonym Full Names
glycoprotein M6A
NCBI Official Symbol
GPM6A
NCBI Official Synonym Symbols
M6A; GPM6
UniProt Protein Name
Neuronal membrane glycoprotein M6-a
Protein Family
Neuronal membrane glycoprotein
UniProt Gene Name
GPM6A
UniProt Synonym Gene Names
M6A; M6a
UniProt Entry Name
GPM6A_HUMAN
NCBI Protein Information
neuronal membrane glycoprotein M6-a

UniProt Comments for GPM6A

GPM6A: Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. May be involved in neuronal NGF-dependent Ca(2+) influx. May be involved in regulation of endocytosis and intracellular trafficking of G- protein-coupled receptors (GPCRs); enhances internalization and recycling of mu-type opioid receptor. Belongs to the myelin proteolipid protein family.

Protein type: Channel, calcium; Membrane protein, integral; Membrane protein, multi-pass; Cell surface

Chromosomal Location of Human Ortholog: 4q34

Cellular Component: cell soma; dendritic spine; filopodium; integral to membrane; neuron projection; plasma membrane

Molecular Function: calcium channel activity; protein binding

Biological Process: neurite morphogenesis; neuron migration; positive regulation of filopodium formation; stem cell differentiation; synaptogenesis
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Research Articles on GPM6A

1. findings thus indicate a critical role of correct GPM6A/M6 levels for cognitive function and support a role of the GPM6A duplication for the patient's phenotype

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-GPM6A antibody

 Disease Name  Pubmed Publications
 Learning Disorders Antibodies  >2 publications with GPM6A and Learning Disorders
 Brain Diseases Antibodies  >2 publications with GPM6A and Brain Diseases
 Cognition Disorders Antibodies  >2 publications with GPM6A and Cognition Disorders
 Drug-Related Side Effects and Adverse Reactions Antibodies  >1 publications with GPM6A and Drug-Related Side Effects and Adverse Reactions
 Carcinoma Antibodies  >1 publications with GPM6A and Carcinoma
 Memory Disorders Antibodies  >1 publications with GPM6A and Memory Disorders
 Atrophy Antibodies  >1 publications with GPM6A and Atrophy
 Neoplasms, Experimental Antibodies  >1 publications with GPM6A and Neoplasms, Experimental
 Drug-Induced Liver Injury Antibodies  >1 publications with GPM6A and Drug-Induced Liver Injury
 Fibrosis Antibodies  >1 publications with GPM6A and Fibrosis

Organs/Tissues associated with anti-GPM6A antibody

 Organ/Tissue Name  Pubmed Publications
 Nerve Antibodies  >34 publications with GPM6A and Nerve
 Brain Antibodies  >25 publications with GPM6A and Brain
 Embryonic Tissue Antibodies  >6 publications with GPM6A and Embryonic Tissue
 Liver Antibodies  >2 publications with GPM6A and Liver
 Lung Antibodies  >2 publications with GPM6A and Lung
 Eye Antibodies  >2 publications with GPM6A and Eye
 Kidney Antibodies  >2 publications with GPM6A and Kidney
 Intestine Antibodies  >1 publications with GPM6A and Intestine
 Pancreas Antibodies  >1 publications with GPM6A and Pancreas
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