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GSPT1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS769912

MBS769912 is an antibody targeting GSPT1. Also known as GSPT1 Rabbit Polyclonal. Reactive in Human, Mouse, Rat. Host: Rabbit. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
GSPT1, Polyclonal Antibody
Full Product Name
GSPT1 Rabbit Polyclonal
Product Gene Name
anti-GSPT1 antibody
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid
Purity/Purification
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Preparation and Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)
Molecular Weight
68,700 Da
OMIM
139259
Immunogen
G1 to S phase transition 1
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Applications Tested/Suitable for anti-GSPT1 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

Immunohistochemistry (IHC) of anti-GSPT1 antibody

Immunohistochemistry of paraffin-embedded human breast cancer using MBS769912 (GSPT1 antibody) at dilution of 1:100
Rabbit Anti-GSPT1 Polyclonal Antibody – Cat# MBS769912

Western Blot (WB) of anti-GSPT1 antibody

SGC-7901 cells were subjected to SDS PAGE followed by western blot with MBS769912 (GSPT1 antibody) at dilution of 1:100
Rabbit Anti-GSPT1 Polyclonal Antibody, Western Blot (WB) – Cat# MBS769912

Other Notes

Small volumes of anti-GSPT1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for GSPT1. It may not necessarily be applicable to this product.

NCBI GI #
33874734
NCBI GeneID
2935
NCBI Accession #
AAH09503.2
UniProt Secondary Accession #
Q96GF2; J3KQG6
UniProt Related Accession #
P15170
NCBI Official Full Name
GSPT1 protein
NCBI Official Synonym Full Names
G1 to S phase transition 1
NCBI Official Symbol
GSPT1
NCBI Official Synonym Symbols
GST1; ETF3A; eRF3a; 551G9.2
UniProt Protein Name
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A
UniProt Synonym Protein Names
G1 to S phase transition protein 1 homolog
Protein Family
Eukaryotic peptide chain release factor GTP-binding
UniProt Gene Name
GSPT1
UniProt Synonym Gene Names
ERF3A; Eukaryotic peptide chain release factor subunit 3a; eRF3a
UniProt Entry Name
ERF3A_HUMAN
NCBI Protein Information
eukaryotic peptide chain release factor GTP-binding subunit ERF3A

UniProt Comments for GSPT1

GSPT1 iso3: Involved in translation termination in response to the termination codons UAA, UAG and UGA. Stimulates the activity of ERF1. Involved in regulation of mammalian cell growth. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Belongs to the GTP-binding elongation factor family. ERF3 subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell cycle regulation; Hydrolase; RNA-binding; Translation

Chromosomal Location of Human Ortholog: 16p13.1

Molecular Function: GTPase activity; protein binding; translation release factor activity

Biological Process: G1/S transition of mitotic cell cycle; mRNA catabolic process, nonsense-mediated decay; protein amino acid methylation
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Research Articles on GSPT1

1. GAB2, GSPT1, TFDP2 and ZFPM1 are four new susceptibility loci for testicular germ cell tumor.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-GSPT1 antibody

 Reference Product  PubMed Publications
 PABPC1 antibody  >1 publications with GSPT1 and PABPC1
 ETF1 antibody  >1 publications with GSPT1 and ETF1

Pathways associated with anti-GSPT1 antibody

 Products by Pathway  Pathway Diagram
 MRNA Surveillance Pathway antibodies  MRNA Surveillance Pathway Diagram
 MRNA Surveillance Pathway antibodies  MRNA Surveillance Pathway Diagram

Diseases associated with anti-GSPT1 antibody

 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >3 publications with GSPT1 and Carcinoma
 Breast Neoplasms Antibodies  >3 publications with GSPT1 and Breast Neoplasms
 Adenocarcinoma Antibodies  >2 publications with GSPT1 and Adenocarcinoma
 Precancerous Conditions Antibodies  >1 publications with GSPT1 and Precancerous Conditions
 Liver Diseases Antibodies  >1 publications with GSPT1 and Liver Diseases
 Carcinoma, Hepatocellular Antibodies  >1 publications with GSPT1 and Carcinoma, Hepatocellular
 Anemia Antibodies  >1 publications with GSPT1 and Anemia
 Liver Neoplasms Antibodies  >1 publications with GSPT1 and Liver Neoplasms
 Hypertrophy Antibodies  >1 publications with GSPT1 and Hypertrophy
 Cell Transformation, Neoplastic Antibodies  >1 publications with GSPT1 and Cell Transformation, Neoplastic

Organs/Tissues associated with anti-GSPT1 antibody

 Organ/Tissue Name  Pubmed Publications
 Stomach Antibodies  >3 publications with GSPT1 and Stomach
 Bone Marrow Antibodies  >2 publications with GSPT1 and Bone Marrow
 Blood Antibodies  >2 publications with GSPT1 and Blood
 Bone Antibodies  >2 publications with GSPT1 and Bone
 Lymph Antibodies  >1 publications with GSPT1 and Lymph
 Lymph Node Antibodies  >1 publications with GSPT1 and Lymph Node
 Liver Antibodies  >1 publications with GSPT1 and Liver
 Uncharacterized Tissue Antibodies  >1 publications with GSPT1 and Uncharacterized Tissue
 Lung Antibodies  >1 publications with GSPT1 and Lung
 Nerve Antibodies  >1 publications with GSPT1 and Nerve
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