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GTSE1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS769957

MBS769957 is an antibody targeting GTSE1. Also known as GTSE1 Rabbit Polyclonal. Reactive in Human. Host: Rabbit. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
GTSE1, Polyclonal Antibody
Full Product Name
GTSE1 Rabbit Polyclonal
Product Gene Name
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid
Purity/Purification
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Preparation and Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)
Molecular Weight
76,645 Da
OMIM
607477
Immunogen
G-2 and S-phase expressed 1
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Applications Tested/Suitable for anti-GTSE1 antibody
ELISA (EIA), Western Blot (WB), Immunofluorescence (IF), Immunohistochemistry (IHC)

Immunohistochemistry (IHC) of anti-GTSE1 antibody

Immunohistochemistry of paraffin-embedded human breast cancer using MBS769957 (GTSE1 antibody) at dilution of 1:50
Rabbit Anti-GTSE1 Polyclonal Antibody – Cat# MBS769957

Western Blot (WB) of anti-GTSE1 antibody

L02 cells were subjected to SDS PAGE followed by western blot with MBS769957 (GTSE1 antibody) at dilution of 1:300
Rabbit Anti-GTSE1 Polyclonal Antibody, Western Blot (WB) – Cat# MBS769957

Other Notes

Small volumes of anti-GTSE1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for GTSE1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
G2 and S phase-expressed protein 1
NCBI Official Synonym Full Names
G2 and S-phase expressed 1
NCBI Official Symbol
GTSE1
NCBI Official Synonym Symbols
B99
UniProt Protein Name
G2 and S phase-expressed protein 1
UniProt Synonym Protein Names
Protein B99 homolog
UniProt Gene Name
GTSE1
UniProt Synonym Gene Names
GTSE-1
UniProt Entry Name
GTSE1_HUMAN
NCBI Protein Information
G2 and S phase-expressed protein 1

NCBI Summary for GTSE1

The protein encoded by this gene is only expressed in the S and G2 phases of the cell cycle, where it colocalizes with cytoplasmic tubulin and microtubules. In response to DNA damage, the encoded protein accumulates in the nucleus and binds the tumor suppressor protein p53, shuttling it out of the nucleus and repressing its ability to induce apoptosis. [provided by RefSeq, Jul 2008]
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UniProt Comments for GTSE1

GTSE1: May be involved in p53-induced cell cycle arrest in G2/M phase by interfering with microtubule rearrangements that are required to enter mitosis. Overexpression delays G2/M phase progression.

Protein type: Apoptosis; Cell cycle regulation

Chromosomal Location of Human Ortholog: 22q13.2-q13.3

Cellular Component: cytoplasmic microtubule; cytosol; membrane; nucleoplasm

Molecular Function: protein binding

Biological Process: DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; microtubule-based process; positive regulation of cell migration; positive regulation of protein export from nucleus; proteasomal ubiquitin-dependent protein catabolic process; protein stabilization
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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