Melanocortin 5 Receptor (MC5R) ELISA Kit for Fish

Name: Fish MC5R ELISA Kit; Melanocortin 5 Receptor; MyBioSource
Brand: MyBioSource
SKU: MBS079020
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS079020

Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only! This kit is intended to be used for determination the level of MC5R (hereafter termed "analyte") in undiluted original Fish body fluids, tissue homogenates, secretions or… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

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Product Overview

Online Datasheet in PDF

Product Name

Melanocortin 5 Receptor (MC5R), ELISA Kit

Full Product Name

Fish Melanocortin 5 Receptor ELISA Kit

Product Gene Name

MC5R elisa kit

Species Reactivity

Fish

Assay Type

Sandwich (Quantitative)

Detection Range

0.625ng/ml-20ng/ml.

Sensitivity

0.1ng/ml.

Specificity

No significant cross-reactivity or interference between this analyte and analogues is observed.

Preparation and Storage

Store all reagents at 2-8 degree C

Inter-assay Precision

Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

Intra-assay Precision

Intra-assay CV (%) is less than 15%.

Molecular Weight

36,601 Da

OMIM

600042

3D Structure

ModBase 3D Structure for P33032

Other Notes

Small volumes of MC5R elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MC5R purchase

MBS079020 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Melanocortin 5 Receptor (MC5R) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing MC5R. The ELISA analytical biochemical technique of the MBS079020 kit is based on MC5R antibody-MC5R antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect MC5R antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, MC5R. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for MC5R. It may not necessarily be applicable to this product.

NCBI GI #

5174535

NCBI GeneID

4161

NCBI Accession #

NP_005904.1

UniProt Primary Accession #

P33032

UniProt Secondary Accession #

Q502V1; B0YJ34

UniProt Related Accession #

P33032

GenBank Nucleotide #

NM_005913.2

NCBI Official Full Name

melanocortin receptor 5

NCBI Official Synonym Full Names

melanocortin 5 receptor

NCBI Official Symbol

MC5R

NCBI Official Synonym Symbols

MC2

UniProt Protein Name

Melanocortin receptor 5

UniProt Synonym Protein Names

MC-2

Protein Family

Melanocortin receptor

UniProt Gene Name

MC5R

UniProt Synonym Gene Names

MC5-R

UniProt Entry Name

MC5R_HUMAN

NCBI Protein Information

melanocortin receptor 5; melanocortin-5 receptor

NCBI Summary for MC5R

This gene encodes a member of the seven-pass transmembrane G protein-coupled melanocortin receptor protein family that stimulate cAMP signal transduction. The encoded protein is a receptor for melanocyte-stimulating hormone and adrenocorticotropic hormone and is suggested to play a role in sebum generation. [provided by RefSeq, Jun 2010]

UniProt Comments for MC5R

MC5R: Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. This receptor is a possible mediator of the immunomodulation properties of melanocortins. Belongs to the G-protein coupled receptor 1 family.

Protein type: Receptor, GPCR; Membrane protein, multi-pass; GPCR, family 1; Membrane protein, integral

Chromosomal Location of Human Ortholog: 18p11.2

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: protein binding; hormone binding; melanocortin receptor activity

Biological Process: G-protein signaling, coupled to cyclic nucleotide second messenger; positive regulation of cAMP biosynthetic process

Research Articles on MC5R

1. D115 and D119 in TM3, F195 in TM5, and F254 in TM6 may form a binding pocket for NDP-alpha-MSH binding.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with MC5R elisa kit

Reference Product	PubMed Publications
POMC elisa kit	>89 publications with MC5R and POMC
MC1R elisa kit	>73 publications with MC5R and MC1R
MC4R elisa kit	>65 publications with MC5R and MC4R
MC3R elisa kit	>58 publications with MC5R and MC3R
MC2R elisa kit	>34 publications with MC5R and MC2R
ADRB2 elisa kit	>2 publications with MC5R and ADRB2
GLP1R elisa kit	>1 publications with MC5R and GLP1R
CRH elisa kit	>1 publications with MC5R and CRH

Pathways associated with MC5R elisa kit

Products by Pathway	Pathway Diagram
Class A/1 (Rhodopsin-like Receptors) Pathway antibodies	Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
G Alpha (s) Signalling Events Pathway antibodies	G Alpha (s) Signalling Events Pathway Diagram
GPCR Downstream Signaling Pathway antibodies	GPCR Downstream Signaling Pathway Diagram
GPCR Ligand Binding Pathway antibodies	GPCR Ligand Binding Pathway Diagram
GPCRs, Class A Rhodopsin-like Pathway antibodies	GPCRs, Class A Rhodopsin-like Pathway Diagram
Neuroactive Ligand-receptor Interaction Pathway antibodies	Neuroactive Ligand-receptor Interaction Pathway Diagram
Neuroactive Ligand-receptor Interaction Pathway antibodies	Neuroactive Ligand-receptor Interaction Pathway Diagram
Peptide GPCRs Pathway antibodies	Peptide GPCRs Pathway Diagram
Peptide Ligand-binding Receptors Pathway antibodies	Peptide Ligand-binding Receptors Pathway Diagram
Signal Transduction Pathway antibodies	Signal Transduction Pathway Diagram

Diseases associated with MC5R elisa kit

Disease Name	Pubmed Publications
Inflammation Antibodies	>9 publications with MC5R and Inflammation
Insulin Resistance Antibodies	>3 publications with MC5R and Insulin Resistance
Hypertension Antibodies	>3 publications with MC5R and Hypertension
Pain Antibodies	>3 publications with MC5R and Pain
Mental Disorders Antibodies	>3 publications with MC5R and Mental Disorders
Kidney Diseases Antibodies	>2 publications with MC5R and Kidney Diseases
Learning Disorders Antibodies	>2 publications with MC5R and Learning Disorders
Skin Diseases Antibodies	>2 publications with MC5R and Skin Diseases
Lung Diseases Antibodies	>1 publications with MC5R and Lung Diseases
Fever Antibodies	>1 publications with MC5R and Fever

Organs/Tissues associated with MC5R elisa kit

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>40 publications with MC5R and Brain