Ribonuclease Inhibitor (RI) ELISA Kit for Pigeon

Name: Pigeon RI ELISA Kit; Ribonuclease Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS079922
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS079922

MBS079922 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Ribonuclease Inhibitor, ELISA Kit target analytes in biological samples. The concentration gradients of the kit… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

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Product Overview

Online Datasheet in PDF

Product Name

Ribonuclease Inhibitor, ELISA Kit

Full Product Name

Pigeon Ribonuclease Inhibitor ELISA Kit

Product Gene Name

RI elisa kit

Species Reactivity

Pigeon

Preparation and Storage

Store all reagents at 2-8 degree C

Molecular Weight

49,973 Da

Chromosome Location

Chromosome: 11; NC_000011.9 (494512..507283, complement). Location: 11p15.5

OMIM

173320

3D Structure

ModBase 3D Structure for P13489

Other Notes

Small volumes of RI elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for RI. It may not necessarily be applicable to this product.

NCBI GI #

42822874

NCBI GeneID

6050

NCBI Accession #

NP_976319.1

UniProt Primary Accession #

P13489

UniProt Secondary Accession #

Q8IZK8; Q96FD7; Q9BQ80; Q9UDK6

UniProt Related Accession #

P13489

GenBank Nucleotide #

NM_203385.1

NCBI Official Full Name

ribonuclease inhibitor

NCBI Official Synonym Full Names

ribonuclease/angiogenin inhibitor 1

NCBI Official Symbol

RNH1

NCBI Official Synonym Symbols

RAI; RNH

UniProt Protein Name

Ribonuclease inhibitor

UniProt Synonym Protein Names

Placental ribonuclease inhibitor; Placental RNase inhibitor; Ribonuclease/angiogenin inhibitor 1

Protein Family

Ribonuclease inhibitor

UniProt Gene Name

RNH1

UniProt Synonym Gene Names

PRI; RNH; Placental RNase inhibitor; RAI

UniProt Entry Name

RINI_HUMAN

NCBI Protein Information

ribonuclease inhibitor; placental RNase inhibitor; placental ribonuclease inhibitor

NCBI Summary for RI

Placental ribonuclease inhibitor (PRI) is a member of a family of proteinaceous cytoplasmic RNase inhibitors that occur in many tissues and bind to both intracellular and extracellular RNases (summarized by Lee et al., 1988 [PubMed 3219362]). In addition to control of intracellular RNases, the inhibitor may have a role in the regulation of angiogenin (MIM 105850). Ribonuclease inhibitor, of 50,000 Da, binds to ribonucleases and holds them in a latent form. Since neutral and alkaline ribonucleases probably play a critical role in the turnover of RNA in eukaryotic cells, RNH may be essential for control of mRNA turnover; the interaction of eukaryotic cells with ribonuclease may be reversible in vivo.[supplied by OMIM, Jul 2010]

UniProt Comments for RI

RNH1: Ribonuclease inhibitor which inhibits RNASE1, RNASE2 and ANG. May play a role in redox homeostasis.

Protein type: Inhibitor

Chromosomal Location of Human Ortholog: 11p15.5

Cellular Component: angiogenin-PRI complex; cytoplasm

Molecular Function: protein binding; ribonuclease inhibitor activity

Biological Process: negative regulation of catalytic activity; mRNA catabolic process; regulation of angiogenesis

Research Articles on RI

1. PTEN-mediated miR-21 regulation is achieved by inhibiting the interaction between the Drosha complex and RNH1, revealing previously unidentified role of PTEN in the oncogenic miR-21 biogenesis

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with RI elisa kit

Reference Product	PubMed Publications
ANG elisa kit	>3 publications with RI and ANG
RNASE2 elisa kit	>1 publications with RI and RNASE2

Diseases associated with RI elisa kit

Disease Name	Pubmed Publications
Neoplasms Antibodies	>6 publications with RI and Neoplasms
Drug Toxicity Antibodies	>2 publications with RI and Drug Toxicity
Neoplasm Metastasis Antibodies	>2 publications with RI and Neoplasm Metastasis
Urinary Bladder Neoplasms Antibodies	>2 publications with RI and Urinary Bladder Neoplasms
Mesothelioma Antibodies	>1 publications with RI and Mesothelioma
Fibrosis Antibodies	>1 publications with RI and Fibrosis
Bone Diseases Antibodies	>1 publications with RI and Bone Diseases

Organs/Tissues associated with RI elisa kit

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>3 publications with RI and Blood
Bone Antibodies	>2 publications with RI and Bone
Spleen Antibodies	>1 publications with RI and Spleen
Liver Antibodies	>1 publications with RI and Liver
Pancreas Antibodies	>1 publications with RI and Pancreas
Lung Antibodies	>1 publications with RI and Lung
Uterus Antibodies	>1 publications with RI and Uterus