Mouse Anti-DLGAP1 Monoclonal Antibody – Cat# MBS800106

Western Blot analysis of Rat brain membrane lysate showing detection of SAPAP protein using Mouse Anti-SAPAP Monoclonal Antibody, Clone S127-31. Load: 15 ug. Block: 1.5% BSA for 30 minutes at RT. Primary Antibody: Mouse Anti-SAPAP Monoclonal Antibody at 1:1000 for 2 hours at RT. Secondary Antibody: Sheep Anti-Mouse IgG: HRP for 1 hour at RT.

DLGAP1 Antibody – Mouse Monoclonal

Name: DLGAP1 Antibody; Monoclonal; Mouse; Mouse/Human/Rat-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS800106
Price: 550 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS800106

Background Info: Detects ~120kDa (SAPAP2), ~110kDa (SAPAP1/3/4). It does cross-react with other SAPAPsScientific Background: The SAPAP proteins are thought to be adaptor proteins that also interact with different synaptic scaffolding proteins, cytoskeletal… More details

DISCONTINUED
Click here to view our similar product(s) OR click here to contact our technical support team for suitable replacement.

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

SAPAP (Dlgap1), Monoclonal Antibody

Full Product Name

SAPAP (pan) Antibody: ATTO 390

Product Gene Name

anti-Dlgap1 antibody

Product Synonym Names

Gkap; Dlgap1

Clonality

Monoclonal

Isotype

IgG2b

Clone Number

S127-31

Host

Mouse

Species Reactivity

Mouse, Human, Rat

Form/Format

Protein G Purified

Concentration

1mg/mL (lot specific)

Preparation and Storage

-20 degree C

Molecular Weight

76,043 Da

3D Structure

ModBase 3D Structure for P97836

Conjugate

ATTO 390

Storage Buffer

PBS pH7.4, 50% glycerol, 0.09% sodium azide

Product Categories/Family for anti-Dlgap1 antibody

Neuroscience; Scaffolds

Applications Tested/Suitable for anti-Dlgap1 antibody

Western Blot (WB), Immunocytochemistry (ICC), Immunoprecipitation (IP)

Application Notes for anti-Dlgap1 antibody

1-10ug/mL (WB), 0.1-1.0ug/mL (Perox) (IHC/ICC), 1.0-10ug/mL (IF)

Product References and Citations for anti-Dlgap1 antibody

1. Hille B. (2001) Ion Channels of Excitable Membranes, 3rd Ed., Sinauer Associated Inc.: Sunderland, MA USA. 2. www.iochannels.org 3. Kindler S., et al. (2004) Brain Res. Mol Brain Res. 126: 14-21. 4. Bongiorno-Borbone L., et al. (2005) Biochem, Biophys. Res Commun. 337: 641-646. 5. Welch J.M., Wang D., and Fend G. (2004) J Comp. Neurol. 472: 24-39.

Other Notes

Small volumes of anti-Dlgap1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Dlgap1 purchase

MBS800106 is an antibody targeting Dlgap1. Also known as SAPAP (pan) Antibody: ATTO 390. Reactive in Mouse, Human, Rat. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for Dlgap1. It may not necessarily be applicable to this product.

NCBI GI #

19923689

NCBI GeneID

65040

NCBI Accession #

NP_075235.2

UniProt Primary Accession #

P97836

UniProt Secondary Accession #

O54773; P97841

UniProt Related Accession #

P97836

GenBank Nucleotide #

NM_022946.2

NCBI Official Full Name

disks large-associated protein 1

NCBI Official Synonym Full Names

discs, large (Drosophila) homolog-associated protein 1

NCBI Official Symbol

Dlgap1

NCBI Official Synonym Symbols

Gkap

UniProt Protein Name

Disks large-associated protein 1

UniProt Synonym Protein Names

Guanylate kinase-associated protein; rGKAP; PSD-95/SAP90-binding protein 1; SAP90/PSD-95-associated protein 1; SAPAP1

Protein Family

Disks large-associated protein

UniProt Gene Name

Dlgap1

UniProt Synonym Gene Names

Gkap; DAP-1; rGKAP; SAPAP1

UniProt Entry Name

DLGP1_RAT

NCBI Protein Information

disks large-associated protein 1; DAP-1; rGKAP; SAPAP1; PSD-95/SAP90-binding protein 1; SAP90/PSD-95-associated protein 1; guanylate kinase associated protein; guanylate kinase-associated protein

NCBI Summary for Dlgap1

binds the guanylate kinase-like domain of the PSD-95 family of synaptic ion channel clustering proteins; may play a role in protein-protein interactions at the synaptic junction [RGD, Feb 2006]

UniProt Comments for Dlgap1

SAPAP1: Part of the postsynaptic scaffold in neuronal cells. Belongs to the SAPAP family. 7 isoforms of the human protein are produced by alternative splicing.

Protein type: Cytoskeletal

Cellular Component: postsynaptic membrane; postsynaptic density; synapse; cell junction

Molecular Function: protein domain specific binding; protein binding; protein complex binding

Biological Process: cell-cell signaling

Research Articles on Dlgap1

1. Activity-dependent turnover of postsynnaptic density proteins orchestrated by GKAP is critical for homeostatic plasticity.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-Dlgap1 antibody

Reference Product	PubMed Publications
Dlg1 antibody	>2 publications with Dlgap1 and Dlg1
Dlg4 antibody	>1 publications with Dlgap1 and Dlg4

Pathways associated with anti-Dlgap1 antibody

Products by Pathway	Pathway Diagram
Glutamatergic Synapse Pathway antibodies	Glutamatergic Synapse Pathway Diagram
Glutamatergic Synapse Pathway antibodies	Glutamatergic Synapse Pathway Diagram

Diseases associated with anti-Dlgap1 antibody

Disease Name	Pubmed Publications
Anxiety Disorders Antibodies	>3 publications with Dlgap1 and Anxiety Disorders
Disease Models, Animal Antibodies	>2 publications with Dlgap1 and Disease Models, Animal
Abnormalities, Multiple Antibodies	>1 publications with Dlgap1 and Abnormalities, Multiple

Organs/Tissues associated with anti-Dlgap1 antibody

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>3 publications with Dlgap1 and Brain
Eye Antibodies	>1 publications with Dlgap1 and Eye