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ABCC8 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS800985

Background Info: Detects ~160kDa. Does not cross-react with SUR2BScientific Background: Sulfonylurea receptors (SUR) are membrane proteins which are the molecular targets of the sulfonylurea class of anti-diabetic drugs whose mechanism of action is to promote… More details

$570 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SUR1 (Abcc8), Monoclonal Antibody
Full Product Name
SUR1 Antibody: RPE
Product Gene Name
Product Synonym Names
AM60008PU-N; ABC36; Abcc8; ATP binding cassette sub family C member 8; HHF1; HRINS; MRP8; PHHI; SUR; SUR1; Sulfonylurea receptor (hyperinsulinemia); ATP binding cassette sub family C (CFTR/MRP) member 8
Clonality
Monoclonal
Isotype
IgG1
Clone Number
S289-16
Host
Mouse
Species Reactivity
Mouse, Hamster, Rat
Form/Format
Protein G Purified
Concentration
1mg/mL (lot specific)
Preparation and Storage
-20 degree C
Matching Pairs
Unconjugated Antibody: N/A (MBS800985)
RPE Conjugated Antibody: SUR1 Clone #S289-16 (MBS800985)
Matching Pairs
Unconjugated Antibody: SUR1 Clone #S289-16 (MBS803587)
RPE Conjugated Antibody: SUR1 Clone #S289-16 (MBS800985)
Molecular Weight
177,097 Da
3D Structure
ModBase 3D Structure for Q09429
Conjugate
RPE
Storage Buffer
PBS pH7.4, 50% glycerol, 0.09% sodium azide

Product Categories/Family for anti-Abcc8 antibody

Applications Tested/Suitable for anti-Abcc8 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC)
Application Notes for anti-Abcc8 antibody
1ug/mL (WB), 0.1-1ug/mL (IHC)

Western Blot (WB) of anti-Abcc8 antibody

Western Blot analysis of Rat Brain Membrane showing detection of ~160 kDa SUR1 protein using Mouse Anti-SUR1 Monoclonal Antibody, Clone S289-16. Lane 1: Molecular Weight Ladder. Lane 2: Rat Brain Membrane. Load: 15 ug. Block: 2% BSA and 2% Skim Milk in 1X TBST. Primary Antibody: Mouse Anti-SUR1 Monoclonal Antibody at 1:200 for 16 hours at 4 degree C. Secondary Antibody: Goat Anti-Mouse IgG: HRP at 1:1000 for 1 hour RT. Color Development: ECL solution for 6 min in RT. Predicted/Observed Size: ~160 kDa.
Mouse Anti-ABCC8 Monoclonal Antibody – Cat# MBS800985

Product References and Citations for anti-Abcc8 antibody

1.   Campbell J.D., Sansom M.S., Ashcroft F.M. (2003) EMBO Resp. 4(11): 1038-1042. 2.   Nichols C.G. (2006) Nature. 440 (7083): 470-476.

Other Notes

Small volumes of anti-Abcc8 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Abcc8 purchase

MBS800985 is an antibody targeting Abcc8. Also known as SUR1 Antibody: RPE. Reactive in Mouse, Hamster, Rat. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for Abcc8. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
ATP-binding cassette sub-family C member 8
NCBI Official Synonym Full Names
ATP-binding cassette, subfamily C (CFTR/MRP), member 8
NCBI Official Symbol
Abcc8
NCBI Official Synonym Symbols
Sur; Sur1
UniProt Protein Name
ATP-binding cassette sub-family C member 8
UniProt Synonym Protein Names
Sulfonylurea receptor 1
UniProt Gene Name
Abcc8
UniProt Synonym Gene Names
Sur; Sur1
UniProt Entry Name
ABCC8_RAT
NCBI Protein Information
ATP-binding cassette sub-family C member 8; sulfonylurea receptor 1; sulphonylurea receptor 1; ATP-binding cassette transporter sub-family C member 8; ATP-binding cassette, sub-family C (CFTR/MRP), member 8

NCBI Summary for Abcc8

binds sulfonylurea; subunit of the ATP-sensitive potassium channel K(ATP), which is composed of Sur1 and the inwardly rectifying K(+) channel subunit, Kir6.2 [RGD, Feb 2006]

UniProt Comments for Abcc8

Subunit of the beta-cell ATP-sensitive potassium channel (KATP). Regulator of ATP-sensitive K+ channels and insulin release.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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