Mouse Anti-SYT7 Monoclonal Antibody – Cat# MBS801737

Western Blot analysis of Rat brain lysates showing detection of Synaptotagmin 7 protein using Mouse Anti-Synaptotagmin 7 Monoclonal Antibody, Clone S275-14. Primary Antibody: Mouse Anti-Synaptotagmin 7 Monoclonal Antibody at 1:100, 1:250, 1:500, and 1:1000.

Synaptotagmin 7 (SYT7) Antibody – Mouse Monoclonal

Name: SYT7 Antibody; Monoclonal; Mouse; Rat/Mouse-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS801737
Price: 570 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS801737

Background Info: Detects ~45kDa. Does not cross-react with Synaptotagmin-6 (or others). Can identify other isoforms bands at ~65kD.Scientific Background: Synaptotagmins constitute a family of membrane trafficking proteins that are characterized by an… More details

$570 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Synaptotagmin 7 (Syt7), Monoclonal Antibody

Full Product Name

Synaptotagmin-7 Antibody: RPE

Product Gene Name

anti-Syt7 antibody

Product Synonym Names

IPCA-7; PCANAP7; Prostate cancer-associated protein 7; SYT-7; SYT7; Synaptotagmin 7; Synaptotagmin VII; SytVII

Clonality

Monoclonal

Isotype

IgG2b

Clone Number

S275-14

Host

Mouse

Species Reactivity

Rat, Mouse

Form/Format

Protein G Purified

Concentration

1mg/mL (lot specific)

Preparation and Storage

-20 degree C

Matching Pairs

Unconjugated Antibody: N/A (MBS801737)
RPE Conjugated Antibody: Synaptotagmin 7 Clone #S275-14 (MBS801737)

Matching Pairs

Unconjugated Antibody: Synaptotagmin 7 Clone #S275-14 (MBS802654)
RPE Conjugated Antibody: Synaptotagmin 7 Clone #S275-14 (MBS801737)

Molecular Weight

45,472 Da

3D Structure

ModBase 3D Structure for Q9R0N7

Conjugate

RPE

Storage Buffer

PBS pH7.4, 50% glycerol, 0.09% sodium azide

Product Categories/Family for anti-Syt7 antibody

Neuroscience

Applications Tested/Suitable for anti-Syt7 antibody

Immunocytochemistry (ICC), Western Blot (WB), Immunohistochemistry (IHC)

Application Notes for anti-Syt7 antibody

1:1000 WB

Product References and Citations for anti-Syt7 antibody

1. Schengrund C.L., et al. (2002) J Biol Chem. 277: 32815. 2. Reichardt L.F., et al. (1981) J Cell Biol. 91:257.

Other Notes

Small volumes of anti-Syt7 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Syt7 purchase

MBS801737 is an antibody targeting Syt7. Also known as Synaptotagmin-7 Antibody: RPE. Reactive in Rat, Mouse. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for Syt7. It may not necessarily be applicable to this product.

NCBI GI #

9055364

NCBI GeneID

54525

NCBI Accession #

NP_061271.1

UniProt Primary Accession #

Q9R0N7

UniProt Secondary Accession #

A4QPF1

UniProt Related Accession #

Q9R0N7

GenBank Nucleotide #

NM_018801.3

NCBI Official Full Name

synaptotagmin-7 alpha isoform

NCBI Official Synonym Full Names

synaptotagmin VII

NCBI Official Symbol

Syt7

NCBI Official Synonym Symbols

AI851541; B230112P13Rik

UniProt Protein Name

Synaptotagmin-7

UniProt Synonym Protein Names

Synaptotagmin VII; SytVII

Protein Family

Synaptotagmin

UniProt Gene Name

Syt7

UniProt Synonym Gene Names

SytVII

UniProt Entry Name

SYT7_MOUSE

NCBI Protein Information

synaptotagmin-7; sytVII; synaptotagmin 7

UniProt Comments for Syt7

SYT7: May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Belongs to the synaptotagmin family.

Protein type: Membrane protein, integral

Cellular Component: membrane; lysosome; integral to membrane; plasma membrane; synapse; cytoplasmic vesicle; cell junction

Molecular Function: clathrin binding; syntaxin binding; calcium-dependent phospholipid binding; metal ion binding; calcium ion binding

Biological Process: vesicle fusion; synaptic vesicle exocytosis; exocytosis; plasma membrane repair; calcium ion-dependent exocytosis of neurotransmitter; regulation of calcium ion-dependent exocytosis

Research Articles on Syt7

1. Ca(2+)-triggered release at a synapse is due to synaptotagmins, with synaptotagmin-7 mediating a slower form of Ca(2+)-triggered release that is normally occluded by faster synaptotagmin-1-induced release but becomes manifest upon synaptotagmin-1 deletion

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-Syt7 antibody

Disease Name	Pubmed Publications
Brain Diseases Antibodies	>3 publications with Syt7 and Brain Diseases
Nervous System Diseases Antibodies	>3 publications with Syt7 and Nervous System Diseases
Movement Disorders Antibodies	>2 publications with Syt7 and Movement Disorders
Disease Models, Animal Antibodies	>2 publications with Syt7 and Disease Models, Animal
Liver Diseases Antibodies	>1 publications with Syt7 and Liver Diseases
Inflammation Antibodies	>1 publications with Syt7 and Inflammation
Necrosis Antibodies	>1 publications with Syt7 and Necrosis

Organs/Tissues associated with anti-Syt7 antibody

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>12 publications with Syt7 and Brain
Pancreas Antibodies	>4 publications with Syt7 and Pancreas
Embryonic Tissue Antibodies	>3 publications with Syt7 and Embryonic Tissue
Kidney Antibodies	>2 publications with Syt7 and Kidney
Intestine Antibodies	>1 publications with Syt7 and Intestine
Skin Antibodies	>1 publications with Syt7 and Skin
Eye Antibodies	>1 publications with Syt7 and Eye