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Piccolo (PCLO) Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS802269

Background Info: No cross-reactivity to Bassoon, band at ~550kDa correspondng to the molecular weight of Piccolo.Scientific Background: Piccolo, also referred to as Aczonin, is a large protein which consists of an N-terminal Zn2+ finger, several… More details

$570 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Piccolo (Pclo), Monoclonal Antibody
Full Product Name
Piccolo Antibody: ATTO 594
Product Gene Name
Product Synonym Names
ACZ; Aczonin; PCLO; Pico; presynaptic cytomatrix protein antibody
Clonality
Monoclonal
Isotype
IgG2b Kappa
Clone Number
6H9-B6
Host
Mouse
Species Reactivity
Human, Rat
Form/Format
Protein G Purified
Concentration
1mg/mL (lot specific)
Preparation and Storage
-20 degree C
Matching Pairs
Unconjugated Antibody: Piccolo Clone #6H9-B6 (MBS802124)
ATTO 594 Conjugated Antibody: Piccolo Clone #6H9-B6 (MBS802269)
Molecular Weight
528,257 Da
3D Structure
ModBase 3D Structure for Q9QYX7
Conjugate
ATTO 594
Storage Buffer
PBS pH7.4, 50% glycerol, 0.09% sodium azide

Product Categories/Family for anti-Pclo antibody

Applications Tested/Suitable for anti-Pclo antibody
Western Blot (WB), ELISA (EIA)

Western Blot (WB) of anti-Pclo antibody

Western Blot analysis of Rat and mouse brain lysates showing detection of Piccolo protein using Mouse Anti-Piccolo Monoclonal Antibody, Clone 6H9-B6. Primary Antibody: Mouse Anti-Piccolo Monoclonal Antibody at 1:1000. (1) Mouse brain lysate; (2) Rat brain lysate.
Mouse Anti-PCLO Monoclonal Antibody – Cat# MBS802269

Product References and Citations for anti-Pclo antibody

1. Gerber S.H., Garcia J., Rizo J., Sudhof T.C. (2001) EMBO J. 20(7): 1605-1619. 2. Wang X., et al. (1999) J Cell Biol. 147(1): 151-162. 3. Dresbach T., et al. (2006) J Biol Chem. 281(9):6038- 6047.

Other Notes

Small volumes of anti-Pclo antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Pclo purchase

MBS802269 is an antibody targeting Pclo. Also known as Piccolo Antibody: ATTO 594. Reactive in Human, Rat. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for Pclo. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
protein piccolo isoform 2
NCBI Official Synonym Full Names
piccolo (presynaptic cytomatrix protein)
NCBI Official Symbol
Pclo
NCBI Official Synonym Symbols
Acz; Pico
UniProt Protein Name
Protein piccolo
UniProt Synonym Protein Names
Aczonin; Brain-derived HLMN protein; Multidomain presynaptic cytomatrix protein
Protein Family
UniProt Gene Name
Pclo
UniProt Synonym Gene Names
Acz
UniProt Entry Name
PCLO_MOUSE
NCBI Protein Information
protein piccolo; aczonin; brain-derived HLMN protein; multidomain presynaptic cytomatrix protein

UniProt Comments for Pclo

piccolo: May act as a scaffolding protein involved in the organization of synaptic active zones and in synaptic vesicle trafficking. 6 isoforms of the human protein are produced by alternative splicing.

Protein type: Cytoskeletal

Cellular Component: cell; postsynaptic density; synapse; intracellular; cell junction

Molecular Function: protein binding; calcium-dependent phospholipid binding; metal ion binding; calcium ion binding; profilin binding

Biological Process: regulation of exocytosis; cAMP-mediated signaling; insulin secretion; cytoskeleton organization and biogenesis; synaptic vesicle targeting
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-Pclo antibody

 Products by Pathway  Pathway Diagram
 Insulin Secretion Pathway antibodies  Insulin Secretion Pathway Diagram
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