Mouse Anti-VCAN Monoclonal Antibody – Cat# MBS802724

Western Blot analysis of Rat Brain Membrane and brain showing detection of 350kDa Versican protein using Mouse Anti-Versican Monoclonal Antibody, Clone S351-23. Lane 1: Molecular Weight Ladder. Lane 2: Rat Brain Membrane and brain. Load: 15 ug. Block: 5% Skim Milk in 1X TBST. Primary Antibody: Mouse Anti-Versican Monoclonal Antibody at 1:200 for 16 hours at 4 degree C. Secondary Antibody: Goat Anti-Mouse IgG: HRP at 1:1000 for 1 hour RT. Color Development: KPL TMB. Predicted/Observed Size: 350kDa. Other Band(s): Multiple other bands.

Versican (VCAN) Antibody – Mouse Monoclonal

Name: VCAN Antibody; Monoclonal; Mouse; Mouse/Rat-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS802724
Price: 575 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS802724

Background Info: Detects >350kDaScientific Background: Versican (chondroitin sulfate proteoglycan 2) is a large extracellular matrix proteoglycan involved in cell growth and differentiation. Important as a structural molecule, versican creates loose and… More details

$575 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Versican (Vcan), Monoclonal Antibody

Full Product Name

Versican Antibody: PerCP

Product Gene Name

anti-Vcan antibody

Product Synonym Names

Chondroitin sulfate proteoglycan 2; CSPG2; ERVR; GHAP; PG-M; VCAN; Chondroitin sulfate proteoglycan 2; Chondroitin sulfate proteoglycan core protein 2; Glial hyaluronate binding protein; Glial hyaluronate-binding protein; Large fibroblast proteoglycan

Clonality

Monoclonal

Isotype

IgG1

Clone Number

S351-23

Host

Mouse

Species Reactivity

Mouse, Rat

Form/Format

Protein G Purified

Concentration

1mg/mL (lot specific)

Preparation and Storage

-20 degree C

Matching Pairs

Unconjugated Antibody: N/A (MBS802724)
PerCP Conjugated Antibody: Versican Clone #S351-23 (MBS802724)

Matching Pairs

Unconjugated Antibody: Versican Clone #S351-23 (MBS803352)
PerCP Conjugated Antibody: Versican Clone #S351-23 (MBS802724)

Molecular Weight

74,177 Da

3D Structure

ModBase 3D Structure for Q62059

Conjugate

PerCP

Storage Buffer

PBS pH7.4, 50% glycerol, 0.09% sodium azide

Product Categories/Family for anti-Vcan antibody

Scaffolds

Applications Tested/Suitable for anti-Vcan antibody

Western Blot (WB), Immunocytochemistry (ICC)

Application Notes for anti-Vcan antibody

1:1000 WB

Product References and Citations for anti-Vcan antibody

1. Dours-Zimmermann M.T. and Zimmermann D.R. (1994) J. Biol. Chem. 52: 32992-32998. 2. Evanko S.P., Angello J.C. and Wight T.N. (1999) Arterioscler. Thromb. Vasc. Biol. 4:1004-1013. 3. Lemire J.M., et al. (1999) Arterioscler. Thromb. Vasc. Biol. 7: 1630-1639. 4.Wight T.N. (2002) Curr. Opin. Cell Biol. 5: 617-623. 5. Touab M., Villena J., Barranco C., Arumi-Uria M. and Bassols A. (2002) Am. J. Pathol. 2: 549-557.

Other Notes

Small volumes of anti-Vcan antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Vcan purchase

MBS802724 is an antibody targeting Vcan. Also known as Versican Antibody: PerCP. Reactive in Mouse, Rat. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for Vcan. It may not necessarily be applicable to this product.

NCBI GI #

66396517

NCBI GeneID

13003

NCBI Accession #

AAH96495

UniProt Primary Accession #

Q62059

UniProt Secondary Accession #

Q62058; Q9CUU0

UniProt Related Accession #

Q62059

NCBI Official Full Name

Versican

NCBI Official Synonym Full Names

versican

NCBI Official Symbol

Vcan

NCBI Official Synonym Symbols

NG2; hdf; PG-M; Cspg2; DPEAAE; PG-M(V0); PG-M(V1); 9430051N09; 5430420N07Rik

UniProt Protein Name

Versican core protein

UniProt Synonym Protein Names

Chondroitin sulfate proteoglycan core protein 2; Chondroitin sulfate proteoglycan 2; Large fibroblast proteoglycan; PG-M

Protein Family

Versican core protein

UniProt Gene Name

Vcan

UniProt Synonym Gene Names

Cspg2; Chondroitin sulfate proteoglycan 2

UniProt Entry Name

CSPG2_MOUSE

NCBI Protein Information

versican core protein; heart defect; PG-M core protein; large fibroblast proteoglycan; chondroitin sulfate proteoglycan 2; chondroitin sulfate proteoglycan core protein 2; Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M)

UniProt Comments for Vcan

CSPG2: May play a role in intercellular signaling and in connecting cells with the extracellular matrix. May take part in the regulation of cell motility, growth and differentiation. Binds hyaluronic acid. Defects in VCAN are the cause of Wagner syndrome type 1 (WGN1). WGN is a dominantly inherited vitreoretinopathy characterized by an optically empty vitreous cavity with fibrillary condensations and a preretinal avascular membrane. Other optical features include progressive chorioretinal atrophy, perivascular sheating, subcapsular cataract and myopia. Systemic manifestations are absent in WGN. Belongs to the aggrecan/versican proteoglycan family. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; Cell adhesion; Secreted; Motility/polarity/chemotaxis

Cellular Component: extracellular matrix; extracellular space; proteinaceous extracellular matrix; cell surface; intracellular membrane-bound organelle; membrane; extracellular region

Molecular Function: extracellular matrix structural constituent; hyaluronic acid binding; calcium ion binding; carbohydrate binding; protein phosphatase binding

Biological Process: osteoblast differentiation; central nervous system development; heart development; regulation of phosphoprotein phosphatase activity; glial cell migration; cell adhesion; skeletal development

Research Articles on Vcan

1. Versican 3'-untranslated region (3'UTR) promotes dermal wound repair and fibroblast migration by regulating miRNA activity.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-Vcan antibody

Products by Pathway	Pathway Diagram
A Tetrasaccharide Linker Sequence Is Required For GAG Synthesis Pathway antibodies	A Tetrasaccharide Linker Sequence Is Required For GAG Synthesis Pathway Diagram
CS/DS Degradation Pathway antibodies	CS/DS Degradation Pathway Diagram
Cell Adhesion Molecules (CAMs) Pathway antibodies	Cell Adhesion Molecules (CAMs) Pathway Diagram
Cell Adhesion Molecules (CAMs) Pathway antibodies	Cell Adhesion Molecules (CAMs) Pathway Diagram
Chondroitin Sulfate Biosynthesis Pathway antibodies	Chondroitin Sulfate Biosynthesis Pathway Diagram
Chondroitin Sulfate/dermatan Sulfate Metabolism Pathway antibodies	Chondroitin Sulfate/dermatan Sulfate Metabolism Pathway Diagram
Dermatan Sulfate Biosynthesis Pathway antibodies	Dermatan Sulfate Biosynthesis Pathway Diagram
Disease Pathway antibodies	Disease Pathway Diagram
ECM Proteoglycans Pathway antibodies	ECM Proteoglycans Pathway Diagram
Extracellular Matrix Organization Pathway antibodies	Extracellular Matrix Organization Pathway Diagram

Organs/Tissues associated with anti-Vcan antibody

Organ/Tissue Name	Pubmed Publications
Other Antibodies	>78 publications with Vcan and Other
Skin Antibodies	>46 publications with Vcan and Skin
Brain Antibodies	>36 publications with Vcan and Brain
Embryonic Tissue Antibodies	>28 publications with Vcan and Embryonic Tissue
Lung Antibodies	>25 publications with Vcan and Lung
Heart Antibodies	>23 publications with Vcan and Heart
Eye Antibodies	>19 publications with Vcan and Eye
Ovary Antibodies	>16 publications with Vcan and Ovary
Liver Antibodies	>11 publications with Vcan and Liver
Prostate Antibodies	>9 publications with Vcan and Prostate