Mouse Anti-SLC38A1 Monoclonal Antibody – Cat# MBS802917

Western Blot analysis of Rat brain membrane lysate showing detection of SLC38A1 protein using Mouse Anti-SLC38A1 Monoclonal Antibody, Clone S104-32. Primary Antibody: Mouse Anti-SLC38A1 Monoclonal Antibody at 1:1000.

SLC38A1 Antibody – Mouse Monoclonal

Name: SLC38A1 Antibody; Monoclonal; Mouse; Human/Mouse/Rat-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS802917
Price: 565 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS802917

Background Info: Detects ~50kDaScientific Background: The sodium-coupled neutral amino acid transporters (SNAT) of the SLC38 gene family include System A subtypes SNAT1, SNAT2 and SNAT4 and System N subtypes SNAT3 and SNAT5. The SLC38 transporters are… More details

$565 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

SNAT1 (Slc38a1), Monoclonal Antibody

Full Product Name

SNAT1 Antibody: FITC

Product Gene Name

anti-Slc38a1 antibody

Product Synonym Names

SLC38A1; amino acids transporter A1; ATA1; NAT2; sodium coupled neutral amino acids transporter 1; Amino acid transporter system A1; N-system amino acid transporter 2; S38A1; SAT1; SNAT 1; Solute carrier family 38 member 1; System A amino acid transporter

Clonality

Monoclonal

Isotype

IgG1

Clone Number

S104-32

Host

Mouse

Species Reactivity

Human, Mouse, Rat

Form/Format

Protein G Purified

Concentration

1mg/mL (lot specific)

Preparation and Storage

-20 degree C

Matching Pairs

Unconjugated Antibody: SNAT1 Clone #S104-32 (MBS802780)
FITC Conjugated Antibody: SNAT1 Clone #S104-32 (MBS802917)

Matching Pairs

Unconjugated Antibody: N/A (MBS802917)
FITC Conjugated Antibody: SNAT1 Clone #S104-32 (MBS802917)

Molecular Weight

53,846 Da

3D Structure

ModBase 3D Structure for Q9JM15

Conjugate

FITC

Storage Buffer

PBS pH7.4, 50% glycerol, 0.09% sodium azide.

Product Categories/Family for anti-Slc38a1 antibody

Transporters

Applications Tested/Suitable for anti-Slc38a1 antibody

Immunohistochemistry (IHC), Western Blot (WB), Immunocytochemistry (ICC)

Application Notes for anti-Slc38a1 antibody

1:1000 (WB)

Product References and Citations for anti-Slc38a1 antibody

1. Hatanaka T., et al. (2000) Biochim. Biophys. Acta 1467: 1-6. 2. Wang H., et al. (2000) Biochem. Biophys. Res. Commun. 273: 1175-1179. 3. Gu S., et al. (2001) J. Biol. Chem. 276: 24137-24144. 4. Freeman T.L., et al. (2002) Arch. Biochem. Biophys. 400: 215-222. 5. Palii S.S., et al. (2004) J. Biol. Chem. 279: 3463-3471. 6. Sidoryk M., et al. (2004) Neuroreport. 15: 575-578. Erratum in: 2004. Neuroreport. 15: 533. 7. Desforges,M., et al. (2006) Am. J. Physiol. Cell. Physiol. 290: 305-312.

Other Notes

Small volumes of anti-Slc38a1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Slc38a1 purchase

MBS802917 is an antibody targeting Slc38a1. Also known as SNAT1 Antibody: FITC. Reactive in Human, Mouse, Rat. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for Slc38a1. It may not necessarily be applicable to this product.

NCBI GI #

20301960

NCBI GeneID

170567

NCBI Accession #

NP_620187.1

UniProt Primary Accession #

Q9JM15

UniProt Related Accession #

Q9JM15

GenBank Nucleotide #

NM_138832.1

NCBI Official Full Name

sodium-coupled neutral amino acid transporter 1

NCBI Official Synonym Full Names

solute carrier family 38, member 1

NCBI Official Symbol

Slc38a1

NCBI Official Synonym Symbols

Ata1; GlnT; Sat1

UniProt Protein Name

Sodium-coupled neutral amino acid transporter 1

UniProt Synonym Protein Names

Amino acid transporter A1; rATA1; Glutamine transporter; N-system amino acid transporter 2; Solute carrier family 38 member 1; System A amino acid transporter 1; System A transporter 2; System N amino acid transporter 1

Protein Family

Sodium-coupled neutral amino acid transporter

UniProt Gene Name

Slc38a1

UniProt Synonym Gene Names

Ata1; Glnt; Sa2; Sat1; Snat1; rATA1

UniProt Entry Name

S38A1_RAT

NCBI Protein Information

sodium-coupled neutral amino acid transporter 1; rATA1; glutamine transporter; system A transporter 2; amino acid transporter A1; amino acid transporter system A1; N-system amino acid transporter 2; system A amino acid transporter 1; system N amino acid transporter 1

NCBI Summary for Slc38a1

Na(+)-dependent glutamine transporter; may modulate presynaptic glutamatergic function [RGD, Feb 2006]

UniProt Comments for Slc38a1

SLC38A1: Functions as a sodium-dependent amino acid transporter. Mediates the saturable, pH-sensitive and electrogenic cotransport of glutamine and sodium ions with a stoichiometry of 1:1. May also transport small zwitterionic and aliphatic amino acids with a lower affinity. May supply glutamatergic and GABAergic neurons with glutamine which is required for the synthesis of the neurotransmitters glutamate and GABA. Belongs to the amino acid/polyamine transporter 2 family.

Protein type: Transporter, SLC family; Membrane protein, multi-pass; Membrane protein, integral; Transporter

Cellular Component: membrane; axon; integral to plasma membrane; plasma membrane

Molecular Function: symporter activity; L-glutamine transmembrane transporter activity; amino acid transmembrane transporter activity

Biological Process: sodium ion transport; glutamine transport

Research Articles on Slc38a1

1. Oxidative stress increases SNAT1 expression and stimulates cysteine uptake in rat cardiomyocytes.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-Slc38a1 antibody

Reference Product	PubMed Publications
Slc1a5 antibody	>5 publications with Slc38a1 and Slc1a5
Slc1a4 antibody	>1 publications with Slc38a1 and Slc1a4
Slc1a3 antibody	>1 publications with Slc38a1 and Slc1a3

Pathways associated with anti-Slc38a1 antibody

Products by Pathway	Pathway Diagram
Amino Acid Transport Across The Plasma Membrane Pathway antibodies	Amino Acid Transport Across The Plasma Membrane Pathway Diagram
Astrocytic Glutamate-Glutamine Uptake And Metabolism Pathway antibodies	Astrocytic Glutamate-Glutamine Uptake And Metabolism Pathway Diagram
GABAergic Synapse Pathway antibodies	GABAergic Synapse Pathway Diagram
GABAergic Synapse Pathway antibodies	GABAergic Synapse Pathway Diagram
Glutamatergic Synapse Pathway antibodies	Glutamatergic Synapse Pathway Diagram
Glutamatergic Synapse Pathway antibodies	Glutamatergic Synapse Pathway Diagram
Neuronal System Pathway antibodies	Neuronal System Pathway Diagram
Neurotransmitter Uptake And Metabolism In Glial Cells Pathway antibodies	Neurotransmitter Uptake And Metabolism In Glial Cells Pathway Diagram
SLC-mediated Transmembrane Transport Pathway antibodies	SLC-mediated Transmembrane Transport Pathway Diagram
Transmembrane Transport Of Small Molecules Pathway antibodies	Transmembrane Transport Of Small Molecules Pathway Diagram

Diseases associated with anti-Slc38a1 antibody

Disease Name	Pubmed Publications
Nervous System Diseases Antibodies	>6 publications with Slc38a1 and Nervous System Diseases
Brain Diseases Antibodies	>5 publications with Slc38a1 and Brain Diseases
Fetal Growth Retardation Antibodies	>4 publications with Slc38a1 and Fetal Growth Retardation
Inflammation Antibodies	>3 publications with Slc38a1 and Inflammation
Liver Neoplasms Antibodies	>1 publications with Slc38a1 and Liver Neoplasms
Seizures Antibodies	>1 publications with Slc38a1 and Seizures
Carcinoma, Hepatocellular Antibodies	>1 publications with Slc38a1 and Carcinoma, Hepatocellular
Precancerous Conditions Antibodies	>1 publications with Slc38a1 and Precancerous Conditions
Fetal Death Antibodies	>1 publications with Slc38a1 and Fetal Death
Breast Neoplasms Antibodies	>1 publications with Slc38a1 and Breast Neoplasms

Organs/Tissues associated with anti-Slc38a1 antibody

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>27 publications with Slc38a1 and Brain
Placenta Antibodies	>13 publications with Slc38a1 and Placenta
Embryonic Tissue Antibodies	>5 publications with Slc38a1 and Embryonic Tissue
Inner Ear Antibodies	>1 publications with Slc38a1 and Inner Ear
Spleen Antibodies	>1 publications with Slc38a1 and Spleen