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Endopdi (TXNDC5) Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS804259

Background Info: Detects a protein with a mass of ~48kDa corresponding to EndoPDIScientific Background: Endothelial protein disulfide isomerase (EndoPDI) is a thioredoxin member of the protein disulfide isomerase family of chaperones. This enzyme has been… More details

$575 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
EndoPDI (TXNDC5), Monoclonal Antibody
Full Product Name
EndoPDI Antibody: ATTO 390
Product Gene Name
Product Synonym Names
TXNDC5; Thioredoxin domain containing 5; ERP46; UNQ364; MGC3178; FLJ21353; FLJ90810; thioredoxin related protein; endothelial protein disulphide isomeras
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
2E7/7
Host
Mouse
Species Reactivity
Human
Form/Format
Protein G Purified
Concentration
1mg/mL (lot specific)
Preparation and Storage
-20 degree C
Matching Pairs
Unconjugated Antibody: EndoPDI Clone #2E7/7 (MBS800813)
ATTO 390 Conjugated Antibody: EndoPDI Clone #2E7/7 (MBS804259)
Matching Pairs
Unconjugated Antibody: N/A (MBS804259)
ATTO 390 Conjugated Antibody: EndoPDI Clone #2E7/7 (MBS804259)
Molecular Weight
36,178 Da
3D Structure
ModBase 3D Structure for Q8NBS9
Conjugate
ATTO 390
Storage Buffer
PBS pH7.4, 50% glyercol, 0.09% sodium azide

Product Categories/Family for anti-TXNDC5 antibody

Applications Tested/Suitable for anti-TXNDC5 antibody
ELISA (EIA), Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes for anti-TXNDC5 antibody
1:200 (WB)

Immunocytochemistry (ICC) of anti-TXNDC5 antibody

Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-EndoPDI Monoclonal Antibody, Clone 2E7/7 . Tissue: Cervical Cancer cell line (HeLa). Species: Human. Fixation: 4% Formaldehyde for 15 min at RT. Primary Antibody: Mouse Anti-EndoPDI Monoclonal Antibody at 1:100 for 60 min at RT. Secondary Antibody: Goat Anti-Mouse ATTO 488 at 1:100 for 60 min at RT. Counterstain: DAPI (blue) nuclear stain at 1:5000 for 5 min RT. Localization: Nucleus, Endoplasmic Reticulum, Endoplasmic Reticulum Lumen. Magnification: 60X.
Mouse Anti-TXNDC5 Monoclonal Antibody – Cat# MBS804259

Product References and Citations for anti-TXNDC5 antibody

1. Sullivan D.C., et al. (2003) J Biol Chem. 278 (47) 47079-47088.

Other Notes

Small volumes of anti-TXNDC5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TXNDC5 purchase

MBS804259 is an antibody targeting TXNDC5. Also known as EndoPDI Antibody: ATTO 390. Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for TXNDC5. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
thioredoxin domain-containing protein 5 isoform 3
NCBI Official Synonym Full Names
thioredoxin domain containing 5 (endoplasmic reticulum)
NCBI Official Symbol
TXNDC5
NCBI Official Synonym Symbols
ERP46; HCC-2; STRF8; PDIA15; UNQ364; ENDOPDI
UniProt Protein Name
Thioredoxin domain-containing protein 5
UniProt Synonym Protein Names
Endoplasmic reticulum resident protein 46; ER protein 46; ERp46; Thioredoxin-like protein p46
UniProt Gene Name
TXNDC5
UniProt Synonym Gene Names
TLP46; UNQ364/PRO700; ER protein 46; ERp46
UniProt Entry Name
TXND5_HUMAN
NCBI Protein Information
thioredoxin domain-containing protein 5; ER protein 46; thioredoxin related protein; thioredoxin-like protein p46; endoplasmic reticulum protein ERp46; endothelial protein disulphide isomerase; endoplasmic reticulum resident protein 46; protein disulfide isomerase family A, member 15

NCBI Summary for TXNDC5

This gene encodes a protein-disulfide isomerase. Its expression is induced by hypoxia and its role may be to protect hypoxic cells from apoptosis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring upstream MUTED (muted homolog) gene. [provided by RefSeq, Dec 2010]
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UniProt Comments for TXNDC5

TXNDC5: Possesses thioredoxin activity. Has been shown to reduce insulin disulfide bonds. Also complements protein disulfide- isomerase deficiency in yeast. Belongs to the protein disulfide isomerase family.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 6p24.3

Cellular Component: lysosomal lumen; endoplasmic reticulum lumen; endoplasmic reticulum

Molecular Function: protein binding; protein disulfide isomerase activity

Biological Process: protein folding; cell redox homeostasis; post-Golgi vesicle-mediated transport; apoptotic cell clearance; negative regulation of apoptosis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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