Aquaporin 2 (AQP2) Antibody – Rabbit Polyclonal

AQP2: Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. Expressed in renal collecting tubules. Belongs to the MIP/aquaporin (TC 1.A.8) family.

Protein type: Membrane protein, integral; Transporter, aquaporin family; Transporter; Membrane protein, multi-pass; Channel, misc.

Cellular Component: cytoplasmic vesicle membrane; protein complex; clathrin-coated vesicle; rough endoplasmic reticulum; lysosome; integral to plasma membrane; basolateral plasma membrane; early endosome; trans-Golgi network; recycling endosome; transport vesicle; membrane; apical plasma membrane; cytoplasm; plasma membrane; cytoplasmic vesicle

Molecular Function: protein binding; water transporter activity; glycerol transmembrane transporter activity; actin binding; water channel activity; PDZ domain binding; glycerol channel activity

Biological Process: glycerol transport; actin filament depolymerization; cellular water homeostasis; response to glucagon stimulus; apoptosis; response to lithium ion; water transport; response to hormone stimulus; cellular response to water deprivation; response to lipopolysaccharide; female pregnancy; response to salt stress; response to starvation; water homeostasis; hyperosmotic response; renal water transport; response to calcium ion; cell volume homeostasis; positive regulation of calcium ion transport; transmembrane transport; response to water deprivation; aging