Aquaporin 2 (AQP2) Antibody – Rabbit Polyclonal

AQP2: Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. Expressed in renal collecting tubules. Belongs to the MIP/aquaporin (TC 1.A.8) family.

Protein type: Channel, misc.; Transporter, aquaporin family; Membrane protein, multi-pass; Membrane protein, integral; Transporter

Cellular Component: cytoplasmic vesicle membrane; protein complex; rough endoplasmic reticulum; clathrin-coated vesicle; basolateral plasma membrane; lysosome; integral to plasma membrane; early endosome; trans-Golgi network; recycling endosome; transport vesicle; membrane; cytoplasm; apical plasma membrane; plasma membrane; cytoplasmic vesicle

Molecular Function: protein binding; water transporter activity; glycerol transmembrane transporter activity; actin binding; water channel activity; glycerol channel activity; PDZ domain binding

Biological Process: actin filament depolymerization; glycerol transport; response to glucagon stimulus; cellular water homeostasis; apoptosis; response to lithium ion; water transport; response to hormone stimulus; response to lipopolysaccharide; cellular response to water deprivation; female pregnancy; response to salt stress; water homeostasis; response to starvation; renal water transport; hyperosmotic response; response to calcium ion; positive regulation of calcium ion transport; cell volume homeostasis; transmembrane transport; response to water deprivation; aging