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TRAK2 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS807375

TRAK2, a member of the TRAK family of adaptor proteins, links mitochondria to microtubule based motors. Localized in dendrites, it is specifically required for dendritic development as it reacts with dynein and dynactin. TRAK2 interferes with kinesin-1… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Trak2, Monoclonal Antibody
Full Product Name
Mouse Anti-Human Trak2 Monoclonal IgG2A
Product Gene Name
Product Synonym Names
Trafficking kinesin-binding protein 2 Antibody; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 3 protein Antibody; GABA-A receptor-interacting factor 1 Antibody; O-GlcNAc transferase-interacting protein of 98 kDa Antibody; EMBL AAH60681.1 Antibody; Ensembl ENSMUSP00000027186 MGI 1918077 Antibody; Als2cr3 Antibody; Grif1 Antibody; Oip98 Antibody; KIAA0549 Antibody; Trak2 Antibody: ATTO 594; Mouse Anti-Human TRAK2 Monoclonal, Clone S390-43; Anti-Trak2; Trak2 Antibody
Clonality
Monoclonal
Isotype
IgG2A
Clone Number
S390-43
Host
Mouse
Species Reactivity
Human, Rat
Purity/Purification
Protein G Purified
Concentration
1 mg/ml (lot specific)
Preparation and Storage
Store at -20 degree C
Molecular Weight
Detects ~100kDa.
OMIM
607334
3D Structure
ModBase 3D Structure for O60296
Immunogen
Fusion protein amino acids 757-914 (C-terminus) of human TRAK2
Immunogen Species
Human
COA
A 1:100 dilution was sufficient for detection of Trak2 in 20 ug of mouse brain lysate by ECL immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
Storage Buffer
PBS pH7.4, 50% glycerol, 0.1% sodium azide
Conjugate
ATTO 594
Cellular Localization
Cytoplasm, Mitochondrion, Early Endosome
Applications Tested/Suitable for anti-Trak2 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
Application Notes for anti-Trak2 antibody
Western Blot: 1:1000

Western Blot (WB) of anti-Trak2 antibody

Western Blot analysis of Rat Brain-Membrane showing detection of ~ 100 kDa TRAK2 protein using Mouse Anti-TRAK2 Monoclonal Antibody, Clone S390-43. Lane 1: MW Ladder. Lane 2: Rat Brain Membrane. Load: 15 ug. Block: 2% GE Healthcare Blocker for 1 hour at RT. Primary Antibody: Mouse Anti-TRAK2 Monoclonal Antibody at 1:1000 for 16 hours at 4 degree C. Secondary Antibody: Goat Anti-Mouse IgG: HRP at 1:200 for 1 hour at RT. Color Development: ECL solution for 6 min at RT. Predicted/Observed Size: ~ 100 kDa.
Mouse Anti-TRAK2 Monoclonal Antibody – Cat# MBS807375

Product References and Citations for anti-Trak2 antibody

1. van Spronsen M. et al. (2013) Neuron. 77(3): 48-502. 2. Grishin A., Li H., Levitan E.S., Zaks E. (2006) J Biol Chem. 281(4): 30104-30111. 3. Beck M., et al. (2002) J Biol Chem. 277(33): 30079-30090.

Other Notes

Small volumes of anti-Trak2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Trak2 purchase

MBS807375 is an antibody targeting Trak2. Also known as Mouse Anti-Human Trak2 Monoclonal IgG2A. Reactive in Human, Rat. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for Trak2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
trafficking kinesin-binding protein 2
NCBI Official Synonym Full Names
trafficking protein, kinesin binding 2
NCBI Official Symbol
TRAK2
NCBI Official Synonym Symbols
GRIF1; MILT2; OIP98; CALS-C; GRIF-1; ALS2CR3
UniProt Protein Name
Trafficking kinesin-binding protein 2
UniProt Synonym Protein Names
Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 3 protein
UniProt Gene Name
TRAK2
UniProt Synonym Gene Names
ALS2CR3; KIAA0549
UniProt Entry Name
TRAK2_HUMAN
NCBI Protein Information
trafficking kinesin-binding protein 2

UniProt Comments for Trak2

TRAK2: an O-glycosylated protein that is widely expressed and that interacts with kinesin and O-GlcNAc transferase (OGT). Interacts with mitochondrial rho GTPase 2 (MIRO-2) forming a link between mitochondria and the trafficking apparatus of the microtubules.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 2q33

Cellular Component: cytoplasm; early endosome; mitochondrion; nucleus; plasma membrane

Molecular Function: enzyme binding; GABA receptor binding; protein binding; receptor binding

Biological Process: protein amino acid O-linked glycosylation; protein targeting; regulation of transcription from RNA polymerase II promoter
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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