Complement Component 3/3a (C3/C3A) (C3A) ELISA Kit for Cat

Name: Cat C3A ELISA Kit; Complement Component 3/3a (C3/C3A); MyBioSource
Brand: MyBioSource
SKU: MBS081391
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS081391

Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only! This kit is intended to be used to determine the level of C3/C3A (hereafter termed "analyte") in undiluted original Goose body fluids and tissue homogenates.… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

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Product Overview

Product Name

Complement Component 3/3A (C3/C3A), ELISA Kit

Full Product Name

Cat Complement Component 3/3A (C3/C3A) ELISA Kit

Product Gene Name

C3a elisa kit

Species Reactivity

Cat

Assay Type

Quantitative Sandwich

Samples

Goose Body Fluids And Tissue Homogenates

Detection Range

15.6ng/ml-500ng/ml

Sensitivity

2.0ng/ml.

Preparation and Storage

Store all reagents at 2-8 degree C

Inter-assay Precision

Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.

Intra-assay Precision

Intra-assay CV (%) is less than 15%

Molecular Weight

53,864 Da

OMIM

605246

3D Structure

ModBase 3D Structure for Q16581

Other Notes

Small volumes of C3a elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for C3a purchase

MBS081391 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Complement Component 3/3A (C3/C3A) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing C3a. The ELISA analytical biochemical technique of the MBS081391 kit is based on C3a antibody-C3a antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect C3a antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, C3a. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for C3a. It may not necessarily be applicable to this product.

NCBI GI #

30385606

NCBI GeneID

719

NCBI Accession #

AAP23198.1

UniProt Primary Accession #

Q16581

UniProt Secondary Accession #

O43771; Q92868

UniProt Related Accession #

Q16581

NCBI Official Full Name

complement component 3a receptor 1

NCBI Official Synonym Full Names

complement component 3a receptor 1

NCBI Official Symbol

C3AR1

NCBI Official Synonym Symbols

AZ3B; C3AR; HNFAG09

UniProt Protein Name

C3a anaphylatoxin chemotactic receptor

UniProt Gene Name

C3AR1

UniProt Synonym Gene Names

AZ3B; C3R1; HNFAG09; C3AR; C3a-R

UniProt Entry Name

C3AR_HUMAN

NCBI Protein Information

C3a anaphylatoxin chemotactic receptor; C3a-R; complement component 3 receptor 1

UniProt Comments for C3a

C3aR: Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production. Belongs to the G-protein coupled receptor 1 family.

Protein type: Receptor, GPCR; Membrane protein, multi-pass; GPCR, family 1; Membrane protein, integral

Chromosomal Location of Human Ortholog: 12p13.31

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: G-protein coupled receptor activity; C3a anaphylatoxin receptor activity; complement component C3a receptor activity; phosphoinositide phospholipase C activity

Biological Process: G-protein coupled receptor protein signaling pathway; positive regulation of angiogenesis; elevation of cytosolic calcium ion concentration; metabolic process; blood circulation; complement receptor mediated signaling pathway; inflammatory response; chemotaxis

Research Articles on C3a

1. C3aR and CD46 activation via intrinsic generation of their respective ligands is an integral part of human Th1 (but not Th2) immunity.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with C3a elisa kit

Reference Product	PubMed Publications
C5AR1 elisa kit	>2 publications with C3a and C5AR1
CXCL16 elisa kit	>1 publications with C3a and CXCL16
CXCL10 elisa kit	>1 publications with C3a and CXCL10
FPR1 elisa kit	>1 publications with C3a and FPR1

Pathways associated with C3a elisa kit

Products by Pathway	Pathway Diagram
Class A/1 (Rhodopsin-like Receptors) Pathway antibodies	Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
Complement And Coagulation Cascades Pathway antibodies	Complement And Coagulation Cascades Pathway Diagram
Complement And Coagulation Cascades Pathway antibodies	Complement And Coagulation Cascades Pathway Diagram
Complement And Coagulation Cascades Pathway antibodies	Complement And Coagulation Cascades Pathway Diagram
G Alpha (i) Signalling Events Pathway antibodies	G Alpha (i) Signalling Events Pathway Diagram
GPCR Downstream Signaling Pathway antibodies	GPCR Downstream Signaling Pathway Diagram
GPCR Ligand Binding Pathway antibodies	GPCR Ligand Binding Pathway Diagram
GPCRs, Class A Rhodopsin-like Pathway antibodies	GPCRs, Class A Rhodopsin-like Pathway Diagram
Neuroactive Ligand-receptor Interaction Pathway antibodies	Neuroactive Ligand-receptor Interaction Pathway Diagram
Neuroactive Ligand-receptor Interaction Pathway antibodies	Neuroactive Ligand-receptor Interaction Pathway Diagram

Diseases associated with C3a elisa kit

Disease Name	Pubmed Publications
Inflammation Antibodies	>4 publications with C3a and Inflammation
Cardiovascular Diseases Antibodies	>3 publications with C3a and Cardiovascular Diseases
Disease Models, Animal Antibodies	>3 publications with C3a and Disease Models, Animal
Arteriosclerosis Antibodies	>2 publications with C3a and Arteriosclerosis
Atherosclerosis Antibodies	>2 publications with C3a and Atherosclerosis
Proteinuria Antibodies	>1 publications with C3a and Proteinuria
Liver Failure Antibodies	>1 publications with C3a and Liver Failure
Kidney Diseases Antibodies	>1 publications with C3a and Kidney Diseases
Lung Diseases Antibodies	>1 publications with C3a and Lung Diseases

Organs/Tissues associated with C3a elisa kit

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>8 publications with C3a and Blood
Eye Antibodies	>3 publications with C3a and Eye
Bone Antibodies	>2 publications with C3a and Bone
Heart Antibodies	>2 publications with C3a and Heart
Lung Antibodies	>2 publications with C3a and Lung
Brain Antibodies	>2 publications with C3a and Brain
Bone Marrow Antibodies	>1 publications with C3a and Bone Marrow
Kidney Antibodies	>1 publications with C3a and Kidney
Uncharacterized Tissue Antibodies	>1 publications with C3a and Uncharacterized Tissue
Connective Tissue Antibodies	>1 publications with C3a and Connective Tissue