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SLC28A2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS820222

MBS820222 is an antibody targeting SLC28A2. Also known as Anti-CNT2 Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit. Rabbit polyclonal antibody to CNT2 More details

$225 / 0.03 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CNT2 (SLC28A2), Polyclonal Antibody
Full Product Name
Anti-CNT2 Antibody
Product Gene Name
anti-SLC28A2 antibody
Product Synonym Names
CNT2; Sodium/nucleoside cotransporter 2; Concentrative nucleoside transporter 2; CNT 2; hCNT2; Na(+)/nucleoside cotransporter 2; Sodium-coupled nucleoside transporter 2; Sodium/purine nucleoside co-transporter; SPNT; Solute carrier family 28 member 2
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purity/Purification
The antibody was purified by immunogen affinity chromatography.
Specificity
Recognizes endogenous levels of CNT2 protein.
Preparation and Storage
Upon receipt aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.
Antibody/Peptide Pairs
CNT2 peptide (MBS822688) is used for blocking the activity of CNT2 antibody (MBS820222)
OMIM
606208
3D Structure
ModBase 3D Structure for O43868
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human CNT2. The exact sequence is proprietary.
Applications Tested/Suitable for anti-SLC28A2 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-SLC28A2 antibody
WB (1/500 - 1/1000), IHC (1/100 - 1/200)

Western Blot (WB) of anti-SLC28A2 antibody

Western blot analysis of CNT2 expression in HEK293T (A) whole cell lysates.
Rabbit Anti-SLC28A2 Polyclonal Antibody – Cat# MBS820222

Immunohistochemistry (IHC) of anti-SLC28A2 antibody

Immunohistochemical analysis of CNT2 staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.
Rabbit Anti-SLC28A2 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS820222

Western Blot (WB) of anti-SLC28A2 antibody

Western blot analysis of CNT2 expression in A549 (A), HepG2 (B) whole cell lysates.
Rabbit Anti-SLC28A2 Polyclonal Antibody, Western Blot (WB) – Cat# MBS820222

Other Notes

Small volumes of anti-SLC28A2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for SLC28A2. It may not necessarily be applicable to this product.

NCBI GI #
227116277
NCBI GeneID
9153
NCBI Accession #
NP_004203.2
UniProt Primary Accession #
O43868
UniProt Secondary Accession #
O43239; Q52LZ0; A8K7F9
UniProt Related Accession #
O43868
GenBank Nucleotide #
NM_004212.3
NCBI Official Full Name
sodium/nucleoside cotransporter 2
NCBI Official Synonym Full Names
solute carrier family 28 (concentrative nucleoside transporter), member 2
NCBI Official Symbol
SLC28A2
NCBI Official Synonym Symbols
CNT2; HCNT2; SPNT1; HsT17153
UniProt Protein Name
Sodium/nucleoside cotransporter 2
UniProt Synonym Protein Names
Concentrative nucleoside transporter 2; CNT 2; hCNT2; Na(+)/nucleoside cotransporter 2; Sodium-coupled nucleoside transporter 2; Sodium/purine nucleoside co-transporter; SPNT; Solute carrier family 28 member 2
Protein Family
Sodium/nucleoside cotransporter
UniProt Gene Name
SLC28A2
UniProt Synonym Gene Names
CNT2; CNT 2; hCNT2; SPNT
UniProt Entry Name
S28A2_HUMAN
NCBI Protein Information
sodium/nucleoside cotransporter 2; SPNT; CNT 2; Na(+)/nucleoside cotransporter 2; solute carrier family 28 member 2; concentrative nucleoside transporter 2; sodium-coupled nucleoside transporter 2; sodium/purine nucleoside co-transporter; solute carrier family 28 (sodium-coupled nucleoside transporter), member 2

UniProt Comments for SLC28A2

SLC28A2: Sodium-dependent and purine-selective transporter. Exhibits the transport characteristics of the nucleoside transport system cif or N1 subtype (N1/cif) (selective for purine nucleosides and uridine). Plays a critical role in specific uptake and salvage of purine nucleosides in kidney and other tissues. Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.

Protein type: Membrane protein, integral; Transporter; Transporter, SLC family; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 15q15

Cellular Component: membrane; integral to plasma membrane; plasma membrane

Molecular Function: purine nucleoside transmembrane transporter activity; nucleoside:sodium symporter activity; nucleoside binding

Biological Process: nucleobase, nucleoside, nucleotide and nucleic acid metabolic process; purine nucleoside transport; transmembrane transport
Show more

Research Articles on SLC28A2

1. association between ribavirin (RBV) serum levels and SLC28A2 rs11854484 genotype, as well as the replicated association of ITPA and SLC28A3 genetic polymorphisms with RBV-induced anemia and treatment response

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-SLC28A2 antibody

 Reference Product  PubMed Publications
 SLC29A2 antibody  >4 publications with SLC28A2 and SLC29A2
 SLC29A1 antibody  >4 publications with SLC28A2 and SLC29A1
 SLC29A4 antibody  >1 publications with SLC28A2 and SLC29A4
 SLC29A3 antibody  >1 publications with SLC28A2 and SLC29A3
 SLC30A4 antibody  >1 publications with SLC28A2 and SLC30A4
 DUOX1 antibody  >1 publications with SLC28A2 and DUOX1
 GATM antibody  >1 publications with SLC28A2 and GATM

Pathways associated with anti-SLC28A2 antibody

 Products by Pathway  Pathway Diagram
 SLC-mediated Transmembrane Transport Pathway antibodies  SLC-mediated Transmembrane Transport Pathway Diagram
 Transmembrane Transport Of Small Molecules Pathway antibodies  Transmembrane Transport Of Small Molecules Pathway Diagram
 Transport Of Nucleosides And Free Purine And Pyrimidine Bases Across The Plasma Membrane Pathway antibodies  Transport Of Nucleosides And Free Purine And Pyrimidine Bases Across The Plasma Membrane Pathway Diagram
 Transport Of Vitamins, Nucleosides, And Related Molecules Pathway antibodies  Transport Of Vitamins, Nucleosides, And Related Molecules Pathway Diagram

Diseases associated with anti-SLC28A2 antibody

 Disease Name  Pubmed Publications
 Hepatitis Antibodies  >4 publications with SLC28A2 and Hepatitis
 Liver Diseases Antibodies  >3 publications with SLC28A2 and Liver Diseases
 Hyperglycemia Antibodies  >1 publications with SLC28A2 and Hyperglycemia
 Kidney Diseases Antibodies  >1 publications with SLC28A2 and Kidney Diseases
 Necrosis Antibodies  >1 publications with SLC28A2 and Necrosis

Organs/Tissues associated with anti-SLC28A2 antibody

 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >2 publications with SLC28A2 and Kidney
 Lung Antibodies  >1 publications with SLC28A2 and Lung
 Connective Tissue Antibodies  >1 publications with SLC28A2 and Connective Tissue
 Intestine Antibodies  >1 publications with SLC28A2 and Intestine
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