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CHD1L Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS820328

MBS820328 is an antibody targeting CHD1L. Reactive in Human, Mouse, Rat. Host: Rabbit. Rabbit polyclonal antibody to CHD1L More details

$225 / 0.03 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CHD1L, Polyclonal Antibody
Full Product Name
Anti-CHD1L Antibody
Product Gene Name
anti-CHD1L antibody
Product Synonym Names
ALC1; Chromodomain-helicase-DNA-binding protein 1-like; Amplified in liver cancer protein 1
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purity/Purification
The antibody was purified by immunogen affinity chromatography.
Specificity
Recognizes endogenous levels of CHD1L protein.
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
Antibody/Peptide Pairs
CHD1L peptide (MBS824329) is used for blocking the activity of CHD1L antibody (MBS820328)
Molecular Weight
69,139 Da
OMIM
613039
3D Structure
ModBase 3D Structure for Q86WJ1
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human CHD1L. The exact sequence is proprietary.
Applications Tested/Suitable for anti-CHD1L antibody
Western Blot (WB)
Application Notes for anti-CHD1L antibody
WB (1/500 - 1/1000)

Western Blot (WB) of anti-CHD1L antibody

Western blot analysis of CHD1L expression in HeLa (A), HEK293T (B) whole cell lysates.
Rabbit Anti-CHD1L Polyclonal Antibody – Cat# MBS820328

Other Notes

Small volumes of anti-CHD1L antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CHD1L. It may not necessarily be applicable to this product.

NCBI GI #
373432615
NCBI GeneID
9557
NCBI Accession #
NP_001243265.1
UniProt Primary Accession #
Q86WJ1
UniProt Secondary Accession #
Q53EZ3; Q5VXX7; Q6DD94; Q6PK83; Q86XH3; Q96HF7; Q96SP3; Q9BVJ1; A5YM64; B4DDE1; B5MDZ7
UniProt Related Accession #
Q86WJ1
GenBank Nucleotide #
NM_001256336.1
NCBI Official Full Name
chromodomain-helicase-DNA-binding protein 1-like isoform 2
NCBI Official Synonym Full Names
chromodomain helicase DNA binding protein 1-like
NCBI Official Symbol
CHD1L
NCBI Official Synonym Symbols
ALC1; CHDL
UniProt Protein Name
Chromodomain-helicase-DNA-binding protein 1-like
UniProt Synonym Protein Names
Amplified in liver cancer protein 1
Protein Family
Chromodomain-helicase-DNA-binding protein
UniProt Gene Name
CHD1L
UniProt Synonym Gene Names
ALC1
UniProt Entry Name
CHD1L_HUMAN
NCBI Protein Information
chromodomain-helicase-DNA-binding protein 1-like; amplified in liver cancer 1; amplified in liver cancer protein 1

NCBI Summary for CHD1L

This gene encodes a DNA helicase protein involved in DNA repair. The protein converts ATP to add poly(ADP-ribose) as it regulates chromatin relaxation following DNA damage. Several alternatively spliced transcripts variants have been described for this gene. [provided by RefSeq, Jan 2012]

UniProt Comments for CHD1L

CHD1L: DNA helicase which plays a role in chromatin-remodeling following DNA damage. Targeted to sites of DNA damage through interaction with poly(ADP-ribose) and functions to regulate chromatin during DNA repair. Able to catalyze nucleosome sliding in an ATP-dependent manner. Helicase activity is strongly stimulated upon poly(ADP-ribose)-binding. Belongs to the SNF2/RAD54 helicase family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.6.4.12; Helicase; DNA-binding

Chromosomal Location of Human Ortholog: 1q12

Cellular Component: nucleoplasm; cytoplasm; plasma membrane; nucleus

Molecular Function: ATP-dependent DNA helicase activity; protein binding; DNA binding; ATPase activity; nucleotide binding; ATP binding

Biological Process: chromatin remodeling; DNA repair; response to DNA damage stimulus; DNA duplex unwinding
Show more

Research Articles on CHD1L

1. CHD1L is now considered to be a novel independent biomarker for progression, prognosis and survival in several solid tumors. [Review]

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-CHD1L antibody

 Disease Name  Pubmed Publications
 Carcinoma, Hepatocellular Antibodies  >14 publications with CHD1L and Carcinoma, Hepatocellular
 Liver Neoplasms Antibodies  >11 publications with CHD1L and Liver Neoplasms
 Liver Diseases Antibodies  >10 publications with CHD1L and Liver Diseases
 Adenocarcinoma Antibodies  >9 publications with CHD1L and Adenocarcinoma
 Cardiovascular Diseases Antibodies  >2 publications with CHD1L and Cardiovascular Diseases
 Mental Disorders Antibodies  >2 publications with CHD1L and Mental Disorders
 Heart Defects, Congenital Antibodies  >1 publications with CHD1L and Heart Defects, Congenital
 Ovarian Neoplasms Antibodies  >1 publications with CHD1L and Ovarian Neoplasms
 Nervous System Diseases Antibodies  >1 publications with CHD1L and Nervous System Diseases
 Liver Cirrhosis Antibodies  >1 publications with CHD1L and Liver Cirrhosis

Organs/Tissues associated with anti-CHD1L antibody

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >13 publications with CHD1L and Liver
 Kidney Antibodies  >2 publications with CHD1L and Kidney
 Embryonic Tissue Antibodies  >2 publications with CHD1L and Embryonic Tissue
 Heart Antibodies  >1 publications with CHD1L and Heart
 Bone Antibodies  >1 publications with CHD1L and Bone
 Uterus Antibodies  >1 publications with CHD1L and Uterus
 Blood Antibodies  >1 publications with CHD1L and Blood
 Vascular Antibodies  >1 publications with CHD1L and Vascular
 Cervix Antibodies  >1 publications with CHD1L and Cervix
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