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HOXD8 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS820386

MBS820386 is an antibody targeting HOXD8. Reactive in Human, Mouse, Rat. Host: Rabbit. Rabbit polyclonal antibody to HOXD8 More details

$225 / 0.03 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
HOXD8, Polyclonal Antibody
Full Product Name
Anti-HOXD8 Antibody
Product Gene Name
Product Synonym Names
HOX4E; Homeobox protein Hox-D8; Homeobox protein Hox-4E; Homeobox protein Hox-5.4
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purity/Purification
The antibody was purified by immunogen affinity chromatography.
Specificity
Recognizes endogenous levels of HOXD8 protein.
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
Antibody/Peptide Pairs
HOXD8 peptide (MBS823677) is used for blocking the activity of HOXD8 antibody (MBS820386)
Molecular Weight
31,363 Da
3D Structure
ModBase 3D Structure for P13378
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human HOXD8. The exact sequence is proprietary.
Applications Tested/Suitable for anti-HOXD8 antibody
Western Blot (WB), Immunoprecipitation (IP)
Application Notes for anti-HOXD8 antibody
WB (1/500 - 1/1000), IP (1/10 - 1/100)

Western Blot (WB) of anti-HOXD8 antibody

Western blot analysis of HOXD8 expression in A375 (A), A431 (B), HepG2 (C), HeLa (D) whole cell lysates.
Rabbit Anti-HOXD8 Polyclonal Antibody – Cat# MBS820386

Other Notes

Small volumes of anti-HOXD8 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for HOXD8. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
homeobox protein Hox-D8 isoform 2
NCBI Official Synonym Full Names
homeobox D8
NCBI Official Symbol
HOXD8
NCBI Official Synonym Symbols
HOX4; HOX4E; HOX5.4
UniProt Protein Name
Homeobox protein Hox-D8
UniProt Synonym Protein Names
Homeobox protein Hox-4.3; Homeobox protein Hox-5.4
Protein Family
UniProt Gene Name
Hoxd8
UniProt Synonym Gene Names
Hox-4.3; Hoxd-8
UniProt Entry Name
HXD8_MOUSE
NCBI Protein Information
homeobox protein Hox-D8; Hox-4.5; homeo box 4E; homeo box D8; homeobox protein 5.4; homeobox protein Hox-4E; homeobox protein Hox-5.4

NCBI Summary for HOXD8

This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located in a cluster on chromosome 2. Deletions that remove the entire HOXD gene cluster or the 5' end of this cluster have been associated with severe limb and genital abnormalities. In addition to effects during embryogenesis, this particular gene may also play a role in adult urogenital tract function. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Dec 2010]
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UniProt Comments for HOXD8

HOXD8: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Antp homeobox family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 2q31.1

Cellular Component: nucleus

Biological Process: transcription, DNA-dependent; skeletal morphogenesis; determination of anterior/posterior axis, embryo; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription from RNA polymerase II promoter
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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