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Ephrin B1 (Py317) (EFNB1) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS820767

MBS820767 is an antibody targeting EFNB1. Also known as Anti-Ephrin B1 (pY317) Phospho Antibody. Reactive in Human, Mouse, Rat, Chicken, Zebrafish. Host: Rabbit. Rabbit polyclonal antibody to Ephrin B1 (pY317) More details

$235 / 0.03 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Ephrin B1 (pY317) (EFNB1), Polyclonal Antibody
Full Product Name
Anti-Ephrin B1 (pY317) Phospho Antibody
Product Gene Name
anti-EFNB1 antibody
Product Synonym Names
EFL3; EPLG2; LERK2; Ephrin-B1; EFL-3; ELK ligand; ELK-L; EPH-related receptor tyrosine kinase ligand 2; LERK-2
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat, Chicken, Zebrafish
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purity/Purification
The antibody was purified by immunogen affinity chromatography.
Specificity
Recognizes endogenous levels of Ephrin B1 (pY317) protein.
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
Antibody/Peptide Pairs
Ephrin B1 (pY317) peptide (MBS824151) is used for blocking the activity of Ephrin B1 (pY317) antibody (MBS820767)
Molecular Weight
38,007 Da
OMIM
gene 304110
3D Structure
ModBase 3D Structure for P98172
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human Ephrin B1. The exact sequence is proprietary.
Applications Tested/Suitable for anti-EFNB1 antibody
Western Blot (WB)
Application Notes for anti-EFNB1 antibody
WB (1/500 - 1/1000)

Western Blot (WB) of anti-EFNB1 antibody

Western blot analysis of Ephrin B1 (pY317) expression in HepG2 (A), NIH3T3 (B), mouse heart (C), rat skeletal muscle (D) whole cell lysates.
Rabbit Anti-EFNB1 Polyclonal Antibody – Cat# MBS820767

Other Notes

Small volumes of anti-EFNB1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for EFNB1. It may not necessarily be applicable to this product.

NCBI GI #
4758248
NCBI GeneID
1947
NCBI Accession #
NP_004420.1
UniProt Primary Accession #
P98172
UniProt Secondary Accession #
D3DVU0
UniProt Related Accession #
P98172
GenBank Nucleotide #
NM_004429.4
NCBI Official Full Name
ephrin-B1
NCBI Official Synonym Full Names
ephrin-B1
NCBI Official Symbol
EFNB1
NCBI Official Synonym Symbols
CFND; CFNS; EFB1; EFL3; EPLG2; Elk-L; LERK2
UniProt Protein Name
Ephrin-B1
UniProt Synonym Protein Names
EFL-3; ELK ligand; ELK-L; EPH-related receptor tyrosine kinase ligand 2; LERK-2
Protein Family
Ephrin
UniProt Gene Name
EFNB1
UniProt Synonym Gene Names
EFL3; EPLG2; LERK2; ELK-L; LERK-2
UniProt Entry Name
EFNB1_HUMAN
NCBI Protein Information
ephrin-B1; EFL-3; LERK-2; ELK ligand; ligand of eph-related kinase 2; eph-related receptor tyrosine kinase ligand 2

NCBI Summary for EFNB1

The protein encoded by this gene is a type I membrane protein and a ligand of Eph-related receptor tyrosine kinases. It may play a role in cell adhesion and function in the development or maintenance of the nervous system. [provided by RefSeq, Jul 2008]

UniProt Comments for EFNB1

EFNB1: a type I membrane protein of the ephrin family. A ligand of Eph-related receptor tyrosine kinases EphB1 and EphA1. Ephrins and ephrin receptors mediate numerous developmental processes, particularly in the nervous system. Ephrin-B1 may play a role in cell adhesion and functions in the development or maintenance of the nervous system. Binding to its receptor induces the collapse of commissural axons/growth cones in vitro. Induced by TNF-alpha. Expressed in brain, heart, placenta, lung, liver, skeletal muscle, kidney, and pancreas.

Protein type: Membrane protein, integral; Ligand, receptor tyrosine kinase

Chromosomal Location of Human Ortholog: Xq12

Cellular Component: integral to plasma membrane; cytoplasm; plasma membrane; synapse; nucleus; lipid raft

Molecular Function: protein binding; ephrin receptor binding

Biological Process: axon guidance; cell-cell signaling; ephrin receptor signaling pathway; positive regulation of T cell proliferation; embryonic pattern specification; cell adhesion; neural crest cell migration

Disease: Craniofrontonasal Syndrome
Show more

Research Articles on EFNB1

1. CNK1 mediates ephrinB1 signaling that promotes cell migration through RhoA and JNK activity.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-EFNB1 antibody

 Reference Product  PubMed Publications
 EPHB2 antibody  >12 publications with EFNB1 and EPHB2
 EPHB1 antibody  >10 publications with EFNB1 and EPHB1
 EPHB3 antibody  >3 publications with EFNB1 and EPHB3
 EPHB6 antibody  >3 publications with EFNB1 and EPHB6
 SRC antibody  >3 publications with EFNB1 and SRC
 PTPN13 antibody  >2 publications with EFNB1 and PTPN13
 RGS3 antibody  >1 publications with EFNB1 and RGS3

Pathways associated with anti-EFNB1 antibody

 Products by Pathway  Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 Developmental Biology Pathway antibodies  Developmental Biology Pathway Diagram
 EPH-Ephrin Signaling Pathway antibodies  EPH-Ephrin Signaling Pathway Diagram
 EPH-ephrin Mediated Repulsion Of Cells Pathway antibodies  EPH-ephrin Mediated Repulsion Of Cells Pathway Diagram
 EPHB Forward Signaling Pathway antibodies  EPHB Forward Signaling Pathway Diagram
 EPHB-mediated Forward Signaling Pathway antibodies  EPHB-mediated Forward Signaling Pathway Diagram
 Ephrin B Reverse Signaling Pathway antibodies  Ephrin B Reverse Signaling Pathway Diagram
 Ephrin Signaling Pathway antibodies  Ephrin Signaling Pathway Diagram

Diseases associated with anti-EFNB1 antibody

 Disease Name  Pubmed Publications
 Craniosynostoses Antibodies  >16 publications with EFNB1 and Craniosynostoses
 Hypertelorism Antibodies  >12 publications with EFNB1 and Hypertelorism
 Frontonasal dysplasia Antibodies  >8 publications with EFNB1 and Frontonasal dysplasia
 Craniofrontonasal dysplasia Antibodies  >7 publications with EFNB1 and Craniofrontonasal dysplasia
 Nervous System Diseases Antibodies  >7 publications with EFNB1 and Nervous System Diseases
 Abnormalities, Multiple Antibodies  >5 publications with EFNB1 and Abnormalities, Multiple
 Inflammation Antibodies  >4 publications with EFNB1 and Inflammation
 Necrosis Antibodies  >3 publications with EFNB1 and Necrosis
 Brain Diseases Antibodies  >3 publications with EFNB1 and Brain Diseases
 Neurobehavioral Manifestations Antibodies  >2 publications with EFNB1 and Neurobehavioral Manifestations

Organs/Tissues associated with anti-EFNB1 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >20 publications with EFNB1 and Brain
 Bone Antibodies  >18 publications with EFNB1 and Bone
 Embryonic Tissue Antibodies  >8 publications with EFNB1 and Embryonic Tissue
 Vascular Antibodies  >7 publications with EFNB1 and Vascular
 Connective Tissue Antibodies  >4 publications with EFNB1 and Connective Tissue
 Muscle Antibodies  >4 publications with EFNB1 and Muscle
 Spleen Antibodies  >3 publications with EFNB1 and Spleen
 Eye Antibodies  >3 publications with EFNB1 and Eye
 Ovary Antibodies  >2 publications with EFNB1 and Ovary
 Kidney Antibodies  >2 publications with EFNB1 and Kidney
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