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NDUFA8 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS820770

MBS820770 is an antibody targeting NDUFA8. Reactive in Human, Mouse, Rat, Bovine, Monkey. Host: Rabbit. Rabbit polyclonal antibody to NDUFA8 More details

$225 / 0.03 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
NDUFA8, Polyclonal Antibody
Full Product Name
Anti-NDUFA8 Antibody
Product Gene Name
anti-NDUFA8 antibody
Product Synonym Names
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8; Complex I-19kD; CI-19kD; Complex I-PGIV; CI-PGIV; NADH-ubiquinone oxidoreductase 19 kDa subunit
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat, Bovine, Monkey
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purity/Purification
The antibody was purified by immunogen affinity chromatography.
Specificity
Recognizes endogenous levels of NDUFA8 protein.
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
Antibody/Peptide Pairs
NDUFA8 peptide (MBS824209) is used for blocking the activity of NDUFA8 antibody (MBS820770)
Molecular Weight
20,105 Da
OMIM
603359
3D Structure
ModBase 3D Structure for P51970
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human NDUFA8. The exact sequence is proprietary.
Applications Tested/Suitable for anti-NDUFA8 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)
Application Notes for anti-NDUFA8 antibody
WB (1/500 - 1/1000), IH (1/100 - 1/200), IP (1/10 - 1/100)

Western Blot (WB) of anti-NDUFA8 antibody

Western blot analysis of NDUFA8 expression in HepG2 (A), MCF7 (B) whole cell lysates.
Rabbit Anti-NDUFA8 Polyclonal Antibody – Cat# MBS820770

Immunohistochemistry (IHC) of anti-NDUFA8 antibody

Immunohistochemical analysis of NDUFA8 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.
Rabbit Anti-NDUFA8 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS820770

Other Notes

Small volumes of anti-NDUFA8 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for NDUFA8. It may not necessarily be applicable to this product.

NCBI GI #
7657369
NCBI GeneID
4702
NCBI Accession #
NP_055037.1
UniProt Primary Accession #
P51970
UniProt Secondary Accession #
Q9Y6N0; B1AM93
UniProt Related Accession #
P51970
GenBank Nucleotide #
NM_014222.2
NCBI Official Full Name
NADH dehydrogenase
NCBI Official Synonym Full Names
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa
NCBI Official Symbol
NDUFA8
NCBI Official Synonym Symbols
PGIV; CI-19KD; CI-PGIV
UniProt Protein Name
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8
UniProt Synonym Protein Names
Complex I-19kD; CI-19kD; Complex I-PGIV; CI-PGIV; NADH-ubiquinone oxidoreductase 19 kDa subunit
Protein Family
NADH dehydrogenase
UniProt Gene Name
NDUFA8
UniProt Synonym Gene Names
CI-19kD; CI-PGIV
UniProt Entry Name
NDUA8_HUMAN
NCBI Protein Information
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8; complex I-19kD; complex I-PGIV; complex I PGIV subunit; NADH:ubiquinone oxidoreductase PGIV subunit; NADH-ubiquinone oxidoreductase 19 kDa subunit

NCBI Summary for NDUFA8

The protein encoded by this gene belongs to the complex I 19 kDA subunit family. Mammalian complex I is composed of 45 different subunits. This protein has NADH dehydrogenase activity and oxidoreductase activity. It plays an important role in transfering electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. [provided by RefSeq, Jul 2008]
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UniProt Comments for NDUFA8

NDUFA8: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Belongs to the complex I NDUFA8 subunit family.

Protein type: Mitochondrial; EC 1.6.99.3; Oxidoreductase; Energy Metabolism - oxidative phosphorylation; EC 1.6.5.3

Chromosomal Location of Human Ortholog: 9q33.2

Cellular Component: mitochondrion; mitochondrial inner membrane; mitochondrial intermembrane space; mitochondrial respiratory chain complex I

Molecular Function: NADH dehydrogenase (ubiquinone) activity; protein complex binding

Biological Process: cellular metabolic process; mitochondrial electron transport, NADH to ubiquinone
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Research Articles on NDUFA8

1. Intra-molecular disulfide bridges and the inter-membrane space localization of three Cx(9)C-containing subunits in human: NDUFS5, NDUFB7 and NDUFA8, are proposed.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-NDUFA8 antibody

 Reference Product  PubMed Publications
 NDUFB7 antibody  >1 publications with NDUFA8 and NDUFB7

Pathways associated with anti-NDUFA8 antibody

 Products by Pathway  Pathway Diagram
 Alzheimer's Disease Pathway antibodies  Alzheimer's Disease Pathway Diagram
 Alzheimer's Disease Pathway antibodies  Alzheimer's Disease Pathway Diagram
 Electron Transport Chain Pathway antibodies  Electron Transport Chain Pathway Diagram
 Huntington's Disease Pathway antibodies  Huntington's Disease Pathway Diagram
 Huntington's Disease Pathway antibodies  Huntington's Disease Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 NADH Dehydrogenase (ubiquinone) 1 Alpha Subcomplex Pathway antibodies  NADH Dehydrogenase (ubiquinone) 1 Alpha Subcomplex Pathway Diagram
 NADH Dehydrogenase (ubiquinone) 1 Alpha Subcomplex Pathway antibodies  NADH Dehydrogenase (ubiquinone) 1 Alpha Subcomplex Pathway Diagram
 Non-alcoholic Fatty Liver Disease (NAFLD) Pathway antibodies  Non-alcoholic Fatty Liver Disease (NAFLD) Pathway Diagram

Diseases associated with anti-NDUFA8 antibody

 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >2 publications with NDUFA8 and Nervous System Diseases
 Heart Diseases Antibodies  >1 publications with NDUFA8 and Heart Diseases
 Breast Neoplasms Antibodies  >1 publications with NDUFA8 and Breast Neoplasms

Organs/Tissues associated with anti-NDUFA8 antibody

 Organ/Tissue Name  Pubmed Publications
 Skin Antibodies  >3 publications with NDUFA8 and Skin
 Muscle Antibodies  >2 publications with NDUFA8 and Muscle
 Heart Antibodies  >1 publications with NDUFA8 and Heart
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