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CLCN6 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS821098

MBS821098 is an antibody targeting CLCN6. Reactive in Human, Rabbit. Host: Rabbit. Rabbit polyclonal antibody to CLCN6 More details

$225 / 0.03 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CLCN6, Polyclonal Antibody
Full Product Name
Anti-CLCN6 Antibody
Product Gene Name
Product Synonym Names
KIAA0046; Chloride transport protein 6; Chloride channel protein 6; ClC-6
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Rabbit
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purity/Purification
The antibody was purified by immunogen affinity chromatography.
Specificity
Recognizes endogenous levels of CLCN6 protein.
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
Antibody/Peptide Pairs
CLCN6 peptide (MBS823989) is used for blocking the activity of CLCN6 antibody (MBS821098)
Molecular Weight
94,660 Da
OMIM
602726
3D Structure
ModBase 3D Structure for P51797
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human CLCN6. The exact sequence is proprietary.
Applications Tested/Suitable for anti-CLCN6 antibody
Western Blot (WB)
Application Notes for anti-CLCN6 antibody
WB (1/500 - 1/1000)

Western Blot (WB) of anti-CLCN6 antibody

Western blot analysis of CLCN6 expression in HEK293A (A), Jurkat (B) whole cell lysates.
Rabbit Anti-CLCN6 Polyclonal Antibody – Cat# MBS821098

Other Notes

Small volumes of anti-CLCN6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CLCN6. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
chloride transport protein 6 isoform 2
NCBI Official Synonym Full Names
chloride channel, voltage-sensitive 6
NCBI Official Symbol
CLCN6
NCBI Official Synonym Symbols
CLC-6
UniProt Protein Name
Chloride transport protein 6
UniProt Synonym Protein Names
Chloride channel protein 6; ClC-6
UniProt Gene Name
CLCN6
UniProt Synonym Gene Names
KIAA0046; ClC-6
UniProt Entry Name
CLCN6_HUMAN
NCBI Protein Information
chloride transport protein 6

NCBI Summary for CLCN6

This gene encodes a member of the voltage-dependent chloride channel protein family. Members of this family can function as either chloride channels or antiporters. This protein is primarily localized to late endosomes and functions as a chloride/proton antiporter. Alternate splicing results in both coding and non-coding variants. Additional alternately spliced variants have been described but their full-length structure is unknown. [provided by RefSeq, Mar 2012]
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UniProt Comments for CLCN6

CLCN6: Chloride transport protein, initially identified as voltage-gated chloride channel. The presence of the conserved gating glutamate residues suggests that is functions as antiporter. Belongs to the chloride channel (TC 2.A.49) family. ClC-6/CLCN6 subfamily. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Transporter, ion channel; Transporter; Channel, chloride; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 1p36

Cellular Component: lysosomal membrane; integral to membrane; endosome membrane

Molecular Function: voltage-gated chloride channel activity; ATP binding; antiporter activity

Biological Process: response to mechanical stimulus; chloride transport; signal transduction; cell volume homeostasis; transmembrane transport
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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