GPRC5B Antibody – Rabbit Polyclonal

The protein encoded by this gene is a member of the type 3 G protein-coupled receptor family. Members of this superfamily are characterized by a signature 7-transmembrane domain motif. The specific function of this protein is unknown; however, this protein may mediate the cellular effects of retinoic acid on the G protein signal transduction cascade. [provided by RefSeq, Jul 2008]

GPRC5B: Unknown. This retinoic acid-inducible G-protein coupled receptor provide evidence for a possible interaction between retinoid and G-protein signaling pathways. Belongs to the G-protein coupled receptor 3 family.

Protein type: Receptor, GPCR; GPCR, family 3; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 16p12

Cellular Component: extracellular space; cell surface; cytoplasmic vesicle membrane; intracellular membrane-bound organelle; nucleolus; plasma membrane; integral to membrane; nucleus; lipid raft

Molecular Function: G-protein coupled receptor activity; G-protein-coupled receptor binding; protein kinase activator activity; protein kinase binding

Biological Process: G-protein coupled receptor protein signaling pathway; positive regulation of I-kappaB kinase/NF-kappaB cascade; locomotory behavior; positive regulation of neuron differentiation; glucose homeostasis; positive regulation of inflammatory response