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S100-A10 (S100A10) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS821315

MBS821315 is an antibody targeting S100A10. Also known as Anti-S100-A10 Antibody. Reactive in Human, Mouse, Rat, Bovine, Pig, Rabbit. Host: Rabbit. Rabbit polyclonal antibody to S100-A10 More details

$225 / 0.03 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
S100-A10 (S100A10), Polyclonal Antibody
Full Product Name
Anti-S100-A10 Antibody
Product Gene Name
Product Synonym Names
ANX2LG; CAL1L; CLP11; Protein S100-A10; Calpactin I light chain; Calpactin-1 light chain; Cellular ligand of annexin II; S100 calcium-binding protein A10; p10 protein; p11
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat, Bovine, Pig, Rabbit
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purity/Purification
The antibody was purified by immunogen affinity chromatography.
Specificity
Recognizes endogenous levels of S100-A10 protein.
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
Antibody/Peptide Pairs
S100-A10 peptide (MBS824030) is used for blocking the activity of S100-A10 antibody (MBS821315)
Molecular Weight
11,203 Da
OMIM
114085
3D Structure
ModBase 3D Structure for P60903
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human S100-A10. The exact sequence is proprietary.
Applications Tested/Suitable for anti-S100A10 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-S100A10 antibody
WB (1/500 - 1/1000), IH (1/100 - 1/200)

Western Blot (WB) of anti-S100A10 antibody

Western blot analysis of S100-A10 expression in HT29 (A), HeLa (B), A431 (C) whole cell lysates.
Rabbit Anti-S100A10 Polyclonal Antibody – Cat# MBS821315

Immunohistochemistry (IHC) of anti-S100A10 antibody

Immunohistochemical analysis of S100-A10 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.
Rabbit Anti-S100A10 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS821315

Other Notes

Small volumes of anti-S100A10 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for S100A10. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
protein S100-A10
NCBI Official Synonym Full Names
S100 calcium binding protein A10
NCBI Official Symbol
S100A10
NCBI Official Synonym Symbols
42C; P11; p10; GP11; ANX2L; CAL1L; CLP11; Ca[1]; ANX2LG
UniProt Protein Name
Protein S100-A10
UniProt Synonym Protein Names
Calpactin I light chain; Calpactin-1 light chain; Cellular ligand of annexin II; S100 calcium-binding protein A10; p10 protein; p11
Protein Family
UniProt Gene Name
S100A10
UniProt Synonym Gene Names
ANX2LG; CAL1L; CLP11
UniProt Entry Name
S10AA_HUMAN
NCBI Protein Information
protein S100-A10; calpactin I light chain; calpactin-1 light chain; cellular ligand of annexin II; annexin II tetramer (AIIt) p11 subunit; annexin II ligand, calpactin I, light polypeptide; S100 calcium binding protein A10 (annexin II ligand, calpactin I, light polypeptide (p11)); S100 calcium-binding protein A10 (annexin II ligand, calpactin I, light polypeptide (p11))

NCBI Summary for S100A10

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in exocytosis and endocytosis. [provided by RefSeq, Jul 2008]
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UniProt Comments for S100A10

S100A10: Because S100A10 induces the dimerization of ANXA2/p36, it may function as a regulator of protein phosphorylation in that the ANXA2 monomer is the preferred target (in vitro) of tyrosine- specific kinase. Heterotetramer containing 2 light chains of S100A10/p11 and 2 heavy chains of ANXA2/p36. Interacts with SCN10A. Belongs to the S-100 family.

Protein type: Calcium-binding

Chromosomal Location of Human Ortholog: 1q21

Cellular Component: extrinsic to plasma membrane; lipid raft

Molecular Function: protein binding; protein homodimerization activity; calcium ion binding; lipid binding

Biological Process: positive regulation of focal adhesion formation; positive regulation of stress fiber formation; protein heterotetramerization; positive regulation of binding; lipid raft formation; membrane budding
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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