Rabbit Anti-GSC2 Polyclonal Antibody – Cat# MBS821366

Western blot analysis of GSC2 expression in HepG2 (A), Jurkat (B) whole cell lysates.

GSC2 Antibody – Rabbit Polyclonal

Name: GSC2 Antibody; Polyclonal; Rabbit; Human/Mouse/Rat-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS821366
Price: 225 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS821366

MBS821366 is an antibody targeting GSC2. Reactive in Human, Mouse, Rat. Host: Rabbit. Rabbit polyclonal antibody to GSC2 More details

$225 / 0.03 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

GSC2, Polyclonal Antibody

Full Product Name

Anti-GSC2 Antibody

Product Gene Name

anti-GSC2 antibody

Product Synonym Names

GSCL; Homeobox protein goosecoid-2; GSC-2; Homeobox protein goosecoid-like; GSC-L

Clonality

Polyclonal

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Form/Format

Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purity/Purification

The antibody was purified by immunogen affinity chromatography.

Specificity

Recognizes endogenous levels of GSC2 protein.

Preparation and Storage

Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.

Antibody/Peptide Pairs

GSC2 peptide (MBS824438) is used for blocking the activity of GSC2 antibody (MBS821366)

Molecular Weight

21,545 Da

OMIM

601845

3D Structure

ModBase 3D Structure for O15499

Immunogen

KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human GSC2. The exact sequence is proprietary.

Applications Tested/Suitable for anti-GSC2 antibody

Western Blot (WB), Immunoprecipitation (IP)

Application Notes for anti-GSC2 antibody

WB (1/500 - 1/1000), IP (1/10 - 1/100)

Other Notes

Small volumes of anti-GSC2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for GSC2. It may not necessarily be applicable to this product.

NCBI GI #

4885363

NCBI GeneID

2928

NCBI Accession #

NP_005306.1

UniProt Primary Accession #

O15499

UniProt Secondary Accession #

P56916

UniProt Related Accession #

O15499

GenBank Nucleotide #

NM_005315.1

NCBI Official Full Name

homeobox protein goosecoid-2

NCBI Official Synonym Full Names

goosecoid homeobox 2

NCBI Official Symbol

GSC2

NCBI Official Synonym Symbols

GSCL

UniProt Protein Name

Homeobox protein goosecoid-2

UniProt Synonym Protein Names

Homeobox protein goosecoid-like; GSC-L

Protein Family

1,3-beta-glucan synthase

UniProt Gene Name

GSC2

UniProt Synonym Gene Names

GSCL; GSC-2; GSC-L

UniProt Entry Name

GSC2_HUMAN

NCBI Protein Information

homeobox protein goosecoid-2; GSC-2; GSC-L

NCBI Summary for GSC2

Goosecoidlike (GSCL), a homeodomain-containing gene, resides in the critical region for VCFS/DGS on 22q11. Velocardiofacial syndrome (VCFS) is a developmental disorder characterized by conotruncal heart defects, craniofacial anomalies, and learning disabilities. VCFS is phenotypically related to DiGeorge syndrome (DGS) and both syndromes are associated with hemizygous 22q11 deletions. Because many of the tissues and structures affected in VCFS/DGS derive from the pharyngeal arches of the developing embryo, it is believed that haploinsufficiency of a gene involved in embryonic development may be responsible for its etiology. The gene is expressed in a limited number of adult tissues, as well as in early human development. [provided by RefSeq, Jul 2008]

UniProt Comments for GSC2

GSC2: May have a role in development. May regulate its own transcription. May bind the bicoid consensus sequence TA. Belongs to the paired homeobox family. Bicoid subfamily.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 22q11.21

Cellular Component: nucleus

Molecular Function: DNA binding; sequence-specific DNA binding; transcription factor activity

Biological Process: regulation of transcription from RNA polymerase II promoter; anatomical structure morphogenesis

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.