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SLC6A17 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS821369

MBS821369 is an antibody targeting SLC6A17. Reactive in Human, Mouse, Rat, Bovine, Dog, Pig. Host: Rabbit. Rabbit polyclonal antibody to SLC6A17 More details

$225 / 0.03 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SLC6A17, Polyclonal Antibody
Full Product Name
Anti-SLC6A17 Antibody
Product Gene Name
anti-SLC6A17 antibody
Product Synonym Names
NTT4; Sodium-dependent neutral amino acid transporter SLC6A17; Sodium-dependent neurotransmitter transporter NTT4; Solute carrier family 6 member 17
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat, Bovine, Dog, Pig
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purity/Purification
The antibody was purified by immunogen affinity chromatography.
Specificity
Recognizes endogenous levels of SLC6A17 protein.
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
Antibody/Peptide Pairs
SLC6A17 peptide (MBS824322) is used for blocking the activity of SLC6A17 antibody (MBS821369)
Molecular Weight
81,001 Da
OMIM
610299
3D Structure
ModBase 3D Structure for Q9H1V8
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human SLC6A17. The exact sequence is proprietary.
Applications Tested/Suitable for anti-SLC6A17 antibody
Western Blot (WB)
Application Notes for anti-SLC6A17 antibody
WB (1/500 - 1/1000)

Western Blot (WB) of anti-SLC6A17 antibody

Western blot analysis of SLC6A17 expression in NCIH460 (A), U251MG (B) whole cell lysates.
Rabbit Anti-SLC6A17 Polyclonal Antibody – Cat# MBS821369

Other Notes

Small volumes of anti-SLC6A17 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for SLC6A17. It may not necessarily be applicable to this product.

NCBI GI #
58219014
NCBI GeneID
388662
NCBI Accession #
NP_001010898.1
UniProt Primary Accession #
Q9H1V8
UniProt Secondary Accession #
Q5T5Q9; A6NEA8; A8K1R7; B9EIR5
UniProt Related Accession #
Q9H1V8
GenBank Nucleotide #
NM_001010898.2
NCBI Official Full Name
sodium-dependent neutral amino acid transporter SLC6A17
NCBI Official Synonym Full Names
solute carrier family 6 (neutral amino acid transporter), member 17
NCBI Official Symbol
SLC6A17
NCBI Official Synonym Symbols
NTT4
UniProt Protein Name
Sodium-dependent neutral amino acid transporter SLC6A17
UniProt Synonym Protein Names
Sodium-dependent neurotransmitter transporter NTT4; Solute carrier family 6 member 17
Protein Family
Sodium-dependent neutral amino acid transporter
UniProt Gene Name
SLC6A17
UniProt Synonym Gene Names
NTT4
UniProt Entry Name
S6A17_HUMAN
NCBI Protein Information
sodium-dependent neutral amino acid transporter SLC6A17; solute carrier family 6, member 17; sodium-dependent neurotransmitter transporter NTT4; solute carrier family 6 (neurotransmitter transporter), member 17; orphan sodium- and chloride-dependent neurotransmitter transporter NTT4

NCBI Summary for SLC6A17

The SLC6 family of proteins, which includes SLC6A17, acts as specific transporters for neurotransmitters, amino acids, and osmolytes like betaine, taurine, and creatine. SLC6 proteins are sodium cotransporters that derive the energy for solute transport from the electrochemical gradient for sodium ions (Hoglund et al., 2005 [PubMed 16125675]).[supplied by OMIM, Mar 2008]
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UniProt Comments for SLC6A17

SLC6A17: Functions as a sodium-dependent vesicular transporter selective for proline, glycine, leucine and alanine. In contrast to other members of this neurotransmitter transporter family, does not appear to be chloride-dependent. Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A17 subfamily.

Protein type: Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 1p13.3

Cellular Component: synaptic vesicle; synaptic vesicle membrane; integral to plasma membrane; cell junction

Molecular Function: neurotransmitter:sodium symporter activity

Biological Process: neutral amino acid transport; leucine transport; glycine transport; alanine transport; neurotransmitter transport; proline transport; transmembrane transport

Disease: Mental Retardation, Autosomal Recessive 48
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Research Articles on SLC6A17

1. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-SLC6A17 antibody

 Organ/Tissue Name  Pubmed Publications
 Nerve Antibodies  >3 publications with SLC6A17 and Nerve
 Brain Antibodies  >1 publications with SLC6A17 and Brain
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