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PLC Beta 3 (Ps537) (PLCB3) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS821418

MBS821418 is an antibody targeting PLCB3. Also known as Anti-PLC beta 3 (pS537) Phospho Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit. Rabbit polyclonal antibody to PLC beta 3 (pS537) More details

$235 / 0.03 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PLC beta 3 (pS537) (PLCB3), Polyclonal Antibody
Full Product Name
Anti-PLC beta 3 (pS537) Phospho Antibody
Product Gene Name
Product Synonym Names
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3; Phosphoinositide phospholipase C-beta-3; Phospholipase C-beta-3; PLC-beta-3
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purity/Purification
The antibody was purified by immunogen affinity chromatography.
Specificity
Recognizes endogenous levels of PLC beta 3 (pS537) protein.
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
Antibody/Peptide Pairs
Molecular Weight
131,205 Da
OMIM
600230
3D Structure
ModBase 3D Structure for Q01970
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human PLC beta 3. The exact sequence is proprietary.
Applications Tested/Suitable for anti-PLCB3 antibody
Western Blot (WB)
Application Notes for anti-PLCB3 antibody
WB (1/500 - 1/1000)

Western Blot (WB) of anti-PLCB3 antibody

Western blot analysis of PLC beta 3 (pS537) expression in HeLa PMA-treated (A), MCF7 UV-treated (B), mouse brain (C), rat brain (D) whole cell lysates.
Rabbit Anti-PLCB3 Polyclonal Antibody – Cat# MBS821418

Other Notes

Small volumes of anti-PLCB3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PLCB3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 isoform 1
NCBI Official Synonym Full Names
phospholipase C, beta 3 (phosphatidylinositol-specific)
NCBI Official Symbol
PLCB3
UniProt Protein Name
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3
UniProt Synonym Protein Names
Phosphoinositide phospholipase C-beta-3; Phospholipase C-beta-3; PLC-beta-3
UniProt Gene Name
PLCB3
UniProt Synonym Gene Names
PLC-beta-3
UniProt Entry Name
PLCB3_HUMAN
NCBI Protein Information
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3; PLC beta 3; PLC-beta-3; phosphoinositide phospholipase C-beta-3

NCBI Summary for PLCB3

This gene encodes a member of the phosphoinositide phospholipase C beta enzyme family that catalyze the production of the secondary messengers diacylglycerol and inositol 1,4,5-triphosphate from phosphatidylinositol in G-protein-linked receptor-mediated signal transduction. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
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UniProt Comments for PLCB3

PLCB3: a phosphatidylinositol-specific phospholipase C. Binds to calmodulin. The activated enzyme produces the second messenger molecules diacylglycerol and inositol 1,4,5-trisphosphate.

Protein type: Carbohydrate Metabolism - inositol phosphate; Phospholipase; EC 3.1.4.11

Chromosomal Location of Human Ortholog: 11q13

Cellular Component: nucleoplasm; protein complex; membrane; cytosol

Molecular Function: calmodulin binding; signal transducer activity; calcium ion binding; phospholipase C activity; phosphoinositide phospholipase C activity

Biological Process: synaptic transmission; inositol phosphate metabolic process; regulation of systemic arterial blood pressure; lipid catabolic process
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-PLCB3 antibody

 Reference Product  PubMed Publications
 CAMK2G antibody  >1 publications with PLCB3 and CAMK2G
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