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TFDP2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS821487

MBS821487 is an antibody targeting TFDP2. Also known as Anti-DP2 Antibody. Reactive in Human, Monkey. Host: Rabbit. Rabbit polyclonal antibody to DP2 More details

$225 / 0.03 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
DP2 (TFDP2), Polyclonal Antibody
Full Product Name
Anti-DP2 Antibody
Product Gene Name
anti-TFDP2 antibody
Product Synonym Names
DP2; Transcription factor Dp-2; E2F dimerization partner 2
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Monkey
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purity/Purification
The antibody was purified by immunogen affinity chromatography.
Specificity
Recognizes endogenous levels of DP2 protein.
Preparation and Storage
Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
Antibody/Peptide Pairs
DP2 peptide (MBS824456) is used for blocking the activity of DP2 antibody (MBS821487)
OMIM
602160
3D Structure
ModBase 3D Structure for Q14188
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human DP2. The exact sequence is proprietary.
Applications Tested/Suitable for anti-TFDP2 antibody
Western Blot (WB)
Application Notes for anti-TFDP2 antibody
WB (1/500 - 1/1000)

Western Blot (WB) of anti-TFDP2 antibody

Western blot analysis of DP2 expression in Jurkat (A), A431 (B), Hep G2 (C), COS7 (D) whole cell lysates.
Rabbit Anti-TFDP2 Polyclonal Antibody – Cat# MBS821487

Other Notes

Small volumes of anti-TFDP2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for TFDP2. It may not necessarily be applicable to this product.

NCBI GI #
296278212
NCBI GeneID
7029
NCBI Accession #
NP_001171609.1
UniProt Primary Accession #
Q14188
UniProt Secondary Accession #
Q13331; Q14187; Q6R754; Q8WU88; Q9UG28; B7Z8C8; B7Z8L5; D3DNG1; E9PFC3; F8WAI2
UniProt Related Accession #
Q14188
GenBank Nucleotide #
NM_001178138.1
NCBI Official Full Name
transcription factor Dp-2 isoform 1
NCBI Official Synonym Full Names
transcription factor Dp-2 (E2F dimerization partner 2)
NCBI Official Symbol
TFDP2
NCBI Official Synonym Symbols
DP2
UniProt Protein Name
Transcription factor Dp-2
UniProt Synonym Protein Names
E2F dimerization partner 2
Protein Family
Transcription factor
UniProt Gene Name
TFDP2
UniProt Synonym Gene Names
DP2
UniProt Entry Name
TFDP2_HUMAN
NCBI Protein Information
transcription factor Dp-2

NCBI Summary for TFDP2

The gene is a member of the transcription factor DP family. The encoded protein forms heterodimers with the E2F transcription factors resulting in transcriptional activation of cell cycle regulated genes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010]

UniProt Comments for TFDP2

TFDP2: Can stimulate E2F-dependent transcription. Binds DNA cooperatively with E2F family members through the E2 recognition site, 5'-TTTC[CG]CGC-3', found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DP2/E2F complex functions in the control of cell-cycle progression from G1 to S phase. The E2F1/DP complex appears to mediate both cell proliferation and apoptosis. Belongs to the E2F/DP family. 6 isoforms of the human protein are produced by alternative splicing.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 3q23

Cellular Component: nucleoplasm; transcription factor complex

Molecular Function: protein domain specific binding; DNA binding; transcription cofactor activity; transcription factor binding; transcription factor activity

Biological Process: transcription initiation from RNA polymerase II promoter; Notch signaling pathway; transcription, DNA-dependent; transforming growth factor beta receptor signaling pathway; gene expression; positive regulation of transcription from RNA polymerase II promoter; mitotic cell cycle
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Research Articles on TFDP2

1. Meta-analysis and genome-wide association study of gene-disease association. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-TFDP2 antibody

 Reference Product  PubMed Publications
 E2F1 antibody  >11 publications with TFDP2 and E2F1
 E2F4 antibody  >7 publications with TFDP2 and E2F4
 E2F5 antibody  >5 publications with TFDP2 and E2F5
 E2F2 antibody  >4 publications with TFDP2 and E2F2
 E2F3 antibody  >3 publications with TFDP2 and E2F3
 E2F6 antibody  >2 publications with TFDP2 and E2F6
 RBL1 antibody  >2 publications with TFDP2 and RBL1
 RB1 antibody  >1 publications with TFDP2 and RB1

Pathways associated with anti-TFDP2 antibody

 Products by Pathway  Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle, Mitotic Pathway antibodies  Cell Cycle, Mitotic Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cyclin D Associated Events In G1 Pathway antibodies  Cyclin D Associated Events In G1 Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 E2F Transcription Factor Network Pathway antibodies  E2F Transcription Factor Network Pathway Diagram
 G0 And Early G1 Pathway antibodies  G0 And Early G1 Pathway Diagram
 G1 Phase Pathway antibodies  G1 Phase Pathway Diagram
 G1 To S Cell Cycle Control Pathway antibodies  G1 To S Cell Cycle Control Pathway Diagram

Diseases associated with anti-TFDP2 antibody

 Disease Name  Pubmed Publications
 Kidney Diseases Antibodies  >4 publications with TFDP2 and Kidney Diseases
 Liver Diseases Antibodies  >3 publications with TFDP2 and Liver Diseases
 Liver Neoplasms Antibodies  >3 publications with TFDP2 and Liver Neoplasms
 Cardiovascular Diseases Antibodies  >2 publications with TFDP2 and Cardiovascular Diseases
 Breast Neoplasms Antibodies  >2 publications with TFDP2 and Breast Neoplasms
 Carcinoma, Hepatocellular Antibodies  >2 publications with TFDP2 and Carcinoma, Hepatocellular
 Disease Models, Animal Antibodies  >1 publications with TFDP2 and Disease Models, Animal
 Drug-Related Side Effects and Adverse Reactions Antibodies  >1 publications with TFDP2 and Drug-Related Side Effects and Adverse Reactions
 Neoplasms, Experimental Antibodies  >1 publications with TFDP2 and Neoplasms, Experimental
 Lung Neoplasms Antibodies  >1 publications with TFDP2 and Lung Neoplasms

Organs/Tissues associated with anti-TFDP2 antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >4 publications with TFDP2 and Blood
 Kidney Antibodies  >4 publications with TFDP2 and Kidney
 Liver Antibodies  >3 publications with TFDP2 and Liver
 Embryonic Tissue Antibodies  >2 publications with TFDP2 and Embryonic Tissue
 Brain Antibodies  >2 publications with TFDP2 and Brain
 Lymph Antibodies  >1 publications with TFDP2 and Lymph
 Uterus Antibodies  >1 publications with TFDP2 and Uterus
 Placenta Antibodies  >1 publications with TFDP2 and Placenta
 Lung Antibodies  >1 publications with TFDP2 and Lung
 Stomach Antibodies  >1 publications with TFDP2 and Stomach
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