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RCC2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS821490

MBS821490 is an antibody targeting RCC2. Reactive in Human, Mouse. Host: Rabbit. Rabbit polyclonal antibody to RCC2 More details

$225 / 0.03 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
RCC2, Polyclonal Antibody
Full Product Name
Anti-RCC2 Antibody
Product Gene Name
Product Synonym Names
KIAA1470; TD60; Protein RCC2; RCC1-like protein TD-60; Telophase disk protein of 60 kDa
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purity/Purification
The antibody was purified by immunogen affinity chromatography.
Specificity
Recognizes endogenous levels of RCC2 protein.
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
Antibody/Peptide Pairs
RCC2 peptide (MBS823220) is used for blocking the activity of RCC2 antibody (MBS821490)
Molecular Weight
56,085 Da
OMIM
609587
3D Structure
ModBase 3D Structure for Q9P258
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human RCC2. The exact sequence is proprietary.
Applications Tested/Suitable for anti-RCC2 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)
Application Notes for anti-RCC2 antibody
WB (1/500 - 1/1000), IH (1/100 - 1/200), IP (1/10 - 1/100)

Western Blot (WB) of anti-RCC2 antibody

Western blot analysis of RCC2 expression in HeLa (A), A549 (B), MOLT4 (C), NIH3T3 (D) whole cell lysates.
Rabbit Anti-RCC2 Polyclonal Antibody – Cat# MBS821490

Immunohistochemistry (IHC) of anti-RCC2 antibody

Immunohistochemical analysis of RCC2 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.
Rabbit Anti-RCC2 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS821490

Other Notes

Small volumes of anti-RCC2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for RCC2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
protein RCC2
NCBI Official Synonym Full Names
regulator of chromosome condensation 2
NCBI Official Symbol
RCC2
NCBI Official Synonym Symbols
TD-60
UniProt Protein Name
Protein RCC2
UniProt Synonym Protein Names
RCC1-like protein TD-60; Telophase disk protein of 60 kDa
Protein Family
UniProt Gene Name
RCC2
UniProt Synonym Gene Names
KIAA1470; TD60
UniProt Entry Name
RCC2_HUMAN
NCBI Protein Information
protein RCC2; RCC1-like protein TD-60; telophase disk protein of 60 kDa

UniProt Comments for RCC2

TD-60: Required for completion of mitosis and cytokinesis. May function as a guanine nucleotide exchange factor for the small GTPase RAC1. Binds preferentially to the nucleotide-free form of RAC1. Interacts with microtubules.

Protein type: GEFs, misc.; Nucleolus; GEFs

Chromosomal Location of Human Ortholog: 1p36.13

Cellular Component: microtubule; nucleolus; midbody; cytosol

Molecular Function: protein binding; microtubule binding; Rac GTPase binding

Biological Process: integrin-mediated signaling pathway; focal adhesion formation; mitosis; endosome organization and biogenesis; cell division; negative regulation of focal adhesion formation; positive regulation of attachment of spindle microtubules to kinetochore; mitotic cell cycle; regulation of cell migration
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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