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SLC43A1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS821651

MBS821651 is an antibody targeting SLC43A1. Reactive in Human, Mouse, Rat. Host: Rabbit. Rabbit polyclonal antibody to SLC43A1 More details

$225 / 0.03 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SLC43A1, Polyclonal Antibody
Full Product Name
Anti-SLC43A1 Antibody
Product Gene Name
anti-SLC43A1 antibody
Product Synonym Names
LAT3; PB39; POV1; Large neutral amino acids transporter small subunit 3; L-type amino acid transporter 3; Prostate cancer overexpressed gene 1 protein; Solute carrier family 43 member 1
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purity/Purification
The antibody was purified by immunogen affinity chromatography.
Specificity
Recognizes endogenous levels of SLC43A1 protein.
Preparation and Storage
Upon receipt aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.
Antibody/Peptide Pairs
SLC43A1 peptide (MBS823688) is used for blocking the activity of SLC43A1 antibody (MBS821651)
OMIM
603733
3D Structure
ModBase 3D Structure for O75387
Entrez Gene
8501 (Human); 72401 (Mouse)
SwissProt
O75387 (Human); Q8BSM7 (Mouse)
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human SLC43A1. The exact sequence is proprietary.
Applications Tested/Suitable for anti-SLC43A1 antibody
Western Blot (WB), Immunofluorescence (IF), Immunocytochemsitry (ICC)
Application Notes for anti-SLC43A1 antibody
WB (1/500 - 1/1000), IF/ICC (1/100 - 1/500)

Western Blot (WB) of anti-SLC43A1 antibody

Western blot analysis of SLC43A1 expression in HEK293T (A), SP2/0 (B), H9C2 (C) whole cell lysates.
(Predicted band size: 61 kD; Observed band size: 61 kD)
Rabbit Anti-SLC43A1 Polyclonal Antibody – Cat# MBS821651

Immunofluorescence (IF) of anti-SLC43A1 antibody

Immunofluorescent analysis of SLC43A1 staining in H9C2 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue).
Rabbit Anti-SLC43A1 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS821651

Other Notes

Small volumes of anti-SLC43A1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for SLC43A1. It may not necessarily be applicable to this product.

NCBI GI #
311771737
NCBI GeneID
8501
NCBI Accession #
NP_001185739.1
UniProt Primary Accession #
O75387
UniProt Secondary Accession #
Q8BSM7
UniProt Related Accession #
O75387
GenBank Nucleotide #
NM_001198810.1
NCBI Official Full Name
large neutral amino acids transporter small subunit 3
NCBI Official Synonym Full Names
solute carrier family 43 (amino acid system L transporter), member 1
NCBI Official Symbol
SLC43A1
NCBI Official Synonym Symbols
LAT3; PB39; POV1; R00504
UniProt Protein Name
Large neutral amino acids transporter small subunit 3
UniProt Synonym Protein Names
L-type amino acid transporter 3; Prostate cancer overexpressed gene 1 protein; Solute carrier family 43 member 1
Protein Family
Large neutral amino acids transporter
UniProt Gene Name
SLC43A1
UniProt Entry Name
LAT3_HUMAN
NCBI Protein Information
large neutral amino acids transporter small subunit 3; SLC43A1; L-type amino acid transporter 3; solute carrier family 43, member 1; prostate cancer overexpressed gene 1 protein

NCBI Summary for SLC43A1

SLC43A1 belongs to the system L family of plasma membrane carrier proteins that transports large neutral amino acids (Babu et al., 2003 [PubMed 12930836]).[supplied by OMIM, Mar 2008]

UniProt Comments for SLC43A1

SLC43A1: Sodium-independent, high affinity transport of large neutral amino acids. Has narrower substrate selectivity compared to SLC7A5 and SLC7A8 and mainly transports branched-chain amino acids and phenylalanine. Plays a role in the development of human prostate cancer, from prostatic intraepithelial neoplasia to invasive prostate cancer. Belongs to the SLC43A transporter (TC 2.A.1.44) family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transporter, SLC family; Transporter

Chromosomal Location of Human Ortholog: 11q12.1

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: L-amino acid transmembrane transporter activity; neutral amino acid transmembrane transporter activity

Biological Process: neutral amino acid transport; amino acid transport; ion transport; transmembrane transport
Show more

Research Articles on SLC43A1

1. LAT3 is a transporter subserving system L2 and should denote a new family of organic solute transporters

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-SLC43A1 antibody

 Reference Product  PubMed Publications
 SLC7A8 antibody  >2 publications with SLC43A1 and SLC7A8

Pathways associated with anti-SLC43A1 antibody

 Products by Pathway  Pathway Diagram
 Amino Acid Transport Across The Plasma Membrane Pathway antibodies  Amino Acid Transport Across The Plasma Membrane Pathway Diagram
 SLC-mediated Transmembrane Transport Pathway antibodies  SLC-mediated Transmembrane Transport Pathway Diagram
 Transmembrane Transport Of Small Molecules Pathway antibodies  Transmembrane Transport Of Small Molecules Pathway Diagram
 Transport Of Inorganic Cations/anions And Amino Acids/oligopeptides Pathway antibodies  Transport Of Inorganic Cations/anions And Amino Acids/oligopeptides Pathway Diagram

Diseases associated with anti-SLC43A1 antibody

 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >2 publications with SLC43A1 and Carcinoma
 Prostatic Neoplasms Antibodies  >2 publications with SLC43A1 and Prostatic Neoplasms
 Heart Failure Antibodies  >1 publications with SLC43A1 and Heart Failure
 Heart Diseases Antibodies  >1 publications with SLC43A1 and Heart Diseases
 Neoplasms, Experimental Antibodies  >1 publications with SLC43A1 and Neoplasms, Experimental
 Disease Models, Animal Antibodies  >1 publications with SLC43A1 and Disease Models, Animal

Organs/Tissues associated with anti-SLC43A1 antibody

 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >4 publications with SLC43A1 and Muscle
 Lung Antibodies  >3 publications with SLC43A1 and Lung
 Prostate Antibodies  >3 publications with SLC43A1 and Prostate
 Kidney Antibodies  >2 publications with SLC43A1 and Kidney
 Liver Antibodies  >2 publications with SLC43A1 and Liver
 Heart Antibodies  >1 publications with SLC43A1 and Heart
 Embryonic Tissue Antibodies  >1 publications with SLC43A1 and Embryonic Tissue
 Intestine Antibodies  >1 publications with SLC43A1 and Intestine
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