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ARHGAP18 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS821705

MBS821705 is an antibody targeting ARHGAP18. Reactive in Human, Monkey. Host: Rabbit. Rabbit polyclonal antibody to ARHGAP18 More details

$225 / 0.03 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ARHGAP18, Polyclonal Antibody
Full Product Name
Anti-ARHGAP18 Antibody
Product Gene Name
Product Synonym Names
Rho GTPase-activating protein 18; MacGAP; Rho-type GTPase-activating protein 18
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Monkey
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purity/Purification
The antibody was purified by immunogen affinity chromatography.
Specificity
Recognizes endogenous levels of ARHGAP18 protein.
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
Antibody/Peptide Pairs
ARHGAP18 peptide (MBS822693) is used for blocking the activity of ARHGAP18 antibody (MBS821705)
Molecular Weight
70,164 Da
OMIM
613351
3D Structure
ModBase 3D Structure for Q8N392
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human ARHGAP18. The exact sequence is proprietary.
Applications Tested/Suitable for anti-ARHGAP18 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)
Application Notes for anti-ARHGAP18 antibody
WB (1/500 - 1/1000), IH (1/100 - 1/200), IP (1/10 - 1/100)

Western Blot (WB) of anti-ARHGAP18 antibody

Western blot analysis of ARHGAP18 expression in MDAMB231 (A), U2OS (B) whole cell lysates.
Rabbit Anti-ARHGAP18 Polyclonal Antibody – Cat# MBS821705

Immunohistochemistry (IHC) of anti-ARHGAP18 antibody

Immunohistochemical analysis of ARHGAP18 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.
Rabbit Anti-ARHGAP18 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS821705

Other Notes

Small volumes of anti-ARHGAP18 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ARHGAP18. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
rho GTPase-activating protein 18
NCBI Official Synonym Full Names
Rho GTPase activating protein 18
NCBI Official Symbol
ARHGAP18
NCBI Official Synonym Symbols
SENEX; MacGAP; bA307O14.2
UniProt Protein Name
Rho GTPase-activating protein 18
UniProt Synonym Protein Names
MacGAP; Rho-type GTPase-activating protein 18
UniProt Gene Name
ARHGAP18
UniProt Entry Name
RHG18_HUMAN
NCBI Protein Information
rho GTPase-activating protein 18; ARHGAP18; rho-type GTPase-activating protein 18

NCBI Summary for ARHGAP18

ARHGAP18 belongs to a family of Rho (see MIM 165390) GTPase-activating proteins that modulate cell signaling (Potkin et al., 2009 [PubMed 19065146]).[supplied by OMIM, Apr 2010]

UniProt Comments for ARHGAP18

ARHGAP18: a GTPase activator for the Rho-type GTPases, converting them to inactive GDP-bound states. Two alternatively-spliced isoforms have been described.

Protein type: GAPs; GAPs, Rac/Rho

Chromosomal Location of Human Ortholog: 6q22.33

Cellular Component: cytosol

Molecular Function: GTPase activator activity

Biological Process: regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction; positive regulation of GTPase activity
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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