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SLC25A21 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS821761

MBS821761 is an antibody targeting SLC25A21. Also known as Anti-ODC Antibody. Reactive in Human. Host: Rabbit. Rabbit polyclonal antibody to ODC More details

$225 / 0.03 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ODC (SLC25A21), Polyclonal Antibody
Full Product Name
Anti-ODC Antibody
Product Gene Name
Product Synonym Names
ODC; Mitochondrial 2-oxodicarboxylate carrier; Solute carrier family 25 member 21
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purity/Purification
The antibody was purified by immunogen affinity chromatography.
Specificity
Recognizes endogenous levels of ODC protein.
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
Antibody/Peptide Pairs
ODC peptide (MBS824102) is used for blocking the activity of ODC antibody (MBS821761)
Molecular Weight
33,117 Da
OMIM
607571
3D Structure
ModBase 3D Structure for Q9BQT8
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human ODC. The exact sequence is proprietary.
Applications Tested/Suitable for anti-SLC25A21 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-SLC25A21 antibody
WB (1/500 - 1/1000), IH (1/100 - 1/200)

Western Blot (WB) of anti-SLC25A21 antibody

Western blot analysis of ODC expression in EFO21 (A) whole cell lysates.
Rabbit Anti-SLC25A21 Polyclonal Antibody – Cat# MBS821761

Immunohistochemistry (IHC) of anti-SLC25A21 antibody

Immunohistochemical analysis of ODC staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.
Rabbit Anti-SLC25A21 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS821761

Other Notes

Small volumes of anti-SLC25A21 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for SLC25A21. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
mitochondrial 2-oxodicarboxylate carrier isoform 2
NCBI Official Synonym Full Names
solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
NCBI Official Symbol
SLC25A21
NCBI Official Synonym Symbols
ODC; ODC1
UniProt Protein Name
Mitochondrial 2-oxodicarboxylate carrier
UniProt Synonym Protein Names
Solute carrier family 25 member 21
UniProt Gene Name
SLC25A21
UniProt Synonym Gene Names
ODC
UniProt Entry Name
ODC_HUMAN
NCBI Protein Information
mitochondrial 2-oxodicarboxylate carrier; solute carrier family 25 member 21; solute carrier family 25 (mitochondrial oxodicarboxylate carrier), member 21

NCBI Summary for SLC25A21

SLC25A21 is a homolog of the S. cerevisiae ODC proteins, mitochondrial carriers that transport C5-C7 oxodicarboxylates across inner mitochondrial membranes. One of the species transported by ODC is 2-oxoadipate, a common intermediate in the catabolism of lysine, tryptophan, and hydroxylysine in mammals. Within mitochondria, 2-oxoadipate is converted into acetyl-CoA.[supplied by OMIM, Apr 2004]
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UniProt Comments for SLC25A21

SLC25A21: Transports C5-C7 oxodicarboxylates across the inner membranes of mitochondria. Can transport 2-oxoadipate, 2- oxoglutarate, adipate, glutarate, and to a lesser extent, pimelate, 2-oxopimelate, 2-aminoadipate, oxaloacetate, and citrate. Belongs to the mitochondrial carrier family.

Protein type: Transporter; Membrane protein, integral; Membrane protein, multi-pass; Mitochondrial; Transporter, SLC family

Chromosomal Location of Human Ortholog: 14q11.2

Cellular Component: mitochondrial inner membrane; integral to membrane

Biological Process: lysine catabolic process; transmembrane transport
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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