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Kir3.3 (KCNJ9) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS821806

MBS821806 is an antibody targeting KCNJ9. Also known as Anti-Kir3.3 Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit. Rabbit polyclonal antibody to Kir3.3 More details

$225 / 0.03 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Kir3.3 (KCNJ9), Polyclonal Antibody
Full Product Name
Anti-Kir3.3 Antibody
Product Gene Name
anti-KCNJ9 antibody
Product Synonym Names
GIRK3; G protein-activated inward rectifier potassium channel 3; GIRK-3; Inward rectifier K(+) channel Kir3.3; Potassium channel, inwardly rectifying subfamily J member 9
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purity/Purification
The antibody was purified by immunogen affinity chromatography.
Specificity
Recognizes endogenous levels of Kir3.3 protein.
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
Antibody/Peptide Pairs
Kir3.3 peptide (MBS823848) is used for blocking the activity of Kir3.3 antibody (MBS821806)
Molecular Weight
44,020 Da
OMIM
600932
3D Structure
ModBase 3D Structure for Q92806
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human Kir3.3. The exact sequence is proprietary.
Applications Tested/Suitable for anti-KCNJ9 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-KCNJ9 antibody
WB (1/500 - 1/1000), IH (1/100 - 1/200)

Western Blot (WB) of anti-KCNJ9 antibody

Western blot analysis of Kir3.3 expression in rat brain (A) whole cell lysates.
Rabbit Anti-KCNJ9 Polyclonal Antibody – Cat# MBS821806

Immunohistochemistry (IHC) of anti-KCNJ9 antibody

Immunohistochemical analysis of Kir3.3 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.
Rabbit Anti-KCNJ9 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS821806

Other Notes

Small volumes of anti-KCNJ9 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for KCNJ9. It may not necessarily be applicable to this product.

NCBI GI #
25121970
NCBI GeneID
3765
NCBI Accession #
NP_004974.2
UniProt Primary Accession #
Q92806
UniProt Secondary Accession #
Q5JW75
UniProt Related Accession #
Q92806
GenBank Nucleotide #
NM_004983.2
NCBI Official Full Name
G protein-activated inward rectifier potassium channel 3
NCBI Official Synonym Full Names
potassium inwardly-rectifying channel, subfamily J, member 9
NCBI Official Symbol
KCNJ9
NCBI Official Synonym Symbols
GIRK3; KIR3.3
UniProt Protein Name
G protein-activated inward rectifier potassium channel 3
UniProt Synonym Protein Names
Inward rectifier K(+) channel Kir3.3; Potassium channel, inwardly rectifying subfamily J member 9
Protein Family
G protein-activated inward rectifier potassium channel
UniProt Gene Name
KCNJ9
UniProt Synonym Gene Names
GIRK3; GIRK-3
UniProt Entry Name
KCNJ9_HUMAN
NCBI Protein Information
G protein-activated inward rectifier potassium channel 3; GIRK-3; inward rectifier K(+) channel Kir3.3; inwardly rectifier K+ channel KIR3.3; G protein-coupled inward rectifier potassium channel; potassium channel, inwardly rectifying subfamily J member 9

NCBI Summary for KCNJ9

Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins. It associates with another G-protein-activated potassium channel to form a heteromultimeric pore-forming complex. [provided by RefSeq, Jul 2008]
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UniProt Comments for KCNJ9

GIRK3: This receptor is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ9 subfamily.

Protein type: Channel, potassium; Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 1q23.2

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: protein binding; G-protein activated inward rectifier potassium channel activity; PDZ domain binding

Biological Process: synaptic transmission; potassium ion import
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Research Articles on KCNJ9

1. This study is the first to identify the expression of GIRK2-4 subunits in human esophageal smooth muscle cells.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-KCNJ9 antibody

 Reference Product  PubMed Publications
 KCNJ3 antibody  >5 publications with KCNJ9 and KCNJ3
 ATP1A2 antibody  >2 publications with KCNJ9 and ATP1A2

Pathways associated with anti-KCNJ9 antibody

 Products by Pathway  Pathway Diagram
 Activation Of G Protein Gated Potassium Channels Pathway antibodies  Activation Of G Protein Gated Potassium Channels Pathway Diagram
 Activation Of GABAB Receptors Pathway antibodies  Activation Of GABAB Receptors Pathway Diagram
 Circadian Entrainment Pathway antibodies  Circadian Entrainment Pathway Diagram
 Circadian Entrainment Pathway antibodies  Circadian Entrainment Pathway Diagram
 Dopaminergic Synapse Pathway antibodies  Dopaminergic Synapse Pathway Diagram
 Dopaminergic Synapse Pathway antibodies  Dopaminergic Synapse Pathway Diagram
 Estrogen Signaling Pathway antibodies  Estrogen Signaling Pathway Diagram
 Estrogen Signaling Pathway antibodies  Estrogen Signaling Pathway Diagram
 G Protein Gated Potassium Channels Pathway antibodies  G Protein Gated Potassium Channels Pathway Diagram
 GABA B Receptor Activation Pathway antibodies  GABA B Receptor Activation Pathway Diagram

Diseases associated with anti-KCNJ9 antibody

 Disease Name  Pubmed Publications
 Congenital Abnormalities Antibodies  >1 publications with KCNJ9 and Congenital Abnormalities

Organs/Tissues associated with anti-KCNJ9 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >21 publications with KCNJ9 and Brain
 Connective Tissue Antibodies  >1 publications with KCNJ9 and Connective Tissue
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