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Cnpase (CNP) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS821831

MBS821831 is an antibody targeting CNP. Also known as Anti-CNPase Antibody. Reactive in Human, Rat, Monkey, Sheep. Host: Rabbit. Rabbit polyclonal antibody to CNPase More details

$225 / 0.03 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CNPase, Polyclonal Antibody
Full Product Name
Anti-CNPase Antibody
Product Gene Name
anti-CNP antibody
Product Synonym Names
2',3'-cyclic-nucleotide 3'-phosphodiesterase; CNP; CNPase
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Rat, Monkey, Sheep
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purity/Purification
The antibody was purified by immunogen affinity chromatography.
Specificity
Recognizes endogenous levels of CNPase protein.
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
Antibody/Peptide Pairs
CNPase peptide (MBS824222) is used for blocking the activity of CNPase antibody (MBS821831)
Molecular Weight
45,099 Da
OMIM
123830
3D Structure
ModBase 3D Structure for P09543
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human CNPase. The exact sequence is proprietary.
Applications Tested/Suitable for anti-CNP antibody
Western Blot (WB), Immunoprecipitation (IP)
Application Notes for anti-CNP antibody
WB (1/500 - 1/1000), IP (1/10 - 1/100)

Western Blot (WB) of anti-CNP antibody

Western blot analysis of CNPase expression in HeLa (A), mouse brain (B), rat brain (C) whole cell lysates.
Rabbit Anti-CNP Polyclonal Antibody – Cat# MBS821831

Immunohistochemistry (IHC) of anti-CNP antibody

Rabbit Anti-CNP Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS821831

Other Notes

Small volumes of anti-CNP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CNP. It may not necessarily be applicable to this product.

NCBI GI #
94721261
NCBI GeneID
1267
NCBI Accession #
NP_149124.3
UniProt Primary Accession #
P09543
UniProt Secondary Accession #
P13233
UniProt Related Accession #
P09543
GenBank Nucleotide #
NM_033133.4
NCBI Official Full Name
2',3'-cyclic-nucleotide 3'-phosphodiesterase
NCBI Official Synonym Full Names
2',3'-cyclic nucleotide 3' phosphodiesterase
NCBI Official Symbol
CNP
NCBI Official Synonym Symbols
CNP1
UniProt Protein Name
2',3'-cyclic-nucleotide 3'-phosphodiesterase
Protein Family
2',3'-cyclic-nucleotide 3'-phosphodiesterase
UniProt Gene Name
CNP
UniProt Synonym Gene Names
CNP; CNPase
UniProt Entry Name
CN37_HUMAN
NCBI Protein Information
2',3'-cyclic-nucleotide 3'-phosphodiesterase; CNPase; 2', 3' cyclic nucleotide 3' phosphohydrolase

UniProt Comments for CNP

CNP: May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin. Exists as monomers and homodimers. Belongs to the cyclic nucleotide phosphodiesterase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Phosphodiesterase; Cell development/differentiation; EC 3.1.4.37

Chromosomal Location of Human Ortholog: 17q21

Cellular Component: microtubule; extracellular space; microvillus; pseudopodium; nucleoplasm; mitochondrial outer membrane; membrane; perinuclear region of cytoplasm; mitochondrial inner membrane; cytoplasm; plasma membrane; melanosome; nucleus

Molecular Function: cyclic nucleotide binding; RNA binding; 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity

Biological Process: synaptic transmission; substantia nigra development; axonogenesis; adult locomotory behavior; response to toxin; forebrain development; oligodendrocyte differentiation; response to lipopolysaccharide; microtubule cytoskeleton organization and biogenesis; regulation of mitochondrial membrane permeability; cyclic nucleotide catabolic process; aging
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Research Articles on CNP

1. kidneys express 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNPase), and renal CNPase mediates in part the renal 2',3'-cAMP-adenosine pathway

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CNP antibody

 Reference Product  PubMed Publications
 MBP antibody  >132 publications with CNP and MBP
 MAG antibody  >54 publications with CNP and MAG

Pathways associated with anti-CNP antibody

 Products by Pathway  Pathway Diagram
 Glial Cell Differentiation Pathway antibodies  Glial Cell Differentiation Pathway Diagram

Diseases associated with anti-CNP antibody

 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >241 publications with CNP and Nervous System Diseases
 Brain Diseases Antibodies  >186 publications with CNP and Brain Diseases
 Disease Models, Animal Antibodies  >97 publications with CNP and Disease Models, Animal
 Inflammation Antibodies  >70 publications with CNP and Inflammation
 Kidney Diseases Antibodies  >51 publications with CNP and Kidney Diseases
 Hypertrophy Antibodies  >43 publications with CNP and Hypertrophy
 Fibrosis Antibodies  >39 publications with CNP and Fibrosis
 Necrosis Antibodies  >38 publications with CNP and Necrosis
 Liver Diseases Antibodies  >25 publications with CNP and Liver Diseases
 Nerve Degeneration Antibodies  >16 publications with CNP and Nerve Degeneration

Organs/Tissues associated with anti-CNP antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >888 publications with CNP and Brain
 Blood Antibodies  >521 publications with CNP and Blood
 Nerve Antibodies  >476 publications with CNP and Nerve
 Vascular Antibodies  >352 publications with CNP and Vascular
 Heart Antibodies  >324 publications with CNP and Heart
 Muscle Antibodies  >312 publications with CNP and Muscle
 Kidney Antibodies  >179 publications with CNP and Kidney
 Bone Antibodies  >119 publications with CNP and Bone
 Spinal Cord Antibodies  >108 publications with CNP and Spinal Cord
 Lung Antibodies  >92 publications with CNP and Lung
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