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MNT Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS822012

MBS822012 is an antibody targeting MNT. Reactive in Human, Mouse, Rat. Host: Rabbit. Rabbit polyclonal antibody to MNT More details

$225 / 0.03 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
MNT, Polyclonal Antibody
Full Product Name
Anti-MNT Antibody
Product Gene Name
Product Synonym Names
BHLHD3; ROX; Max-binding protein MNT; Class D basic helix-loop-helix protein 3; bHLHd3; Myc antagonist MNT; Protein ROX
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purity/Purification
The antibody was purified by immunogen affinity chromatography.
Specificity
Recognizes endogenous levels of MNT protein.
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
Antibody/Peptide Pairs
MNT peptide (MBS822363) is used for blocking the activity of MNT antibody (MBS822012)
Molecular Weight
62,300 Da
OMIM
603039
3D Structure
ModBase 3D Structure for Q99583
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human MNT. The exact sequence is proprietary.
Applications Tested/Suitable for anti-MNT antibody
Western Blot (WB)
Application Notes for anti-MNT antibody
WB (1/500 - 1/1000)

Western Blot (WB) of anti-MNT antibody

Western blot analysis of MNT expression in Jurkat (A), HeLa (B) whole cell lysates.
Rabbit Anti-MNT Polyclonal Antibody – Cat# MBS822012

Other Notes

Small volumes of anti-MNT antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for MNT. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
max-binding protein MNT
NCBI Official Synonym Full Names
MAX network transcriptional repressor
NCBI Official Symbol
MNT
NCBI Official Synonym Symbols
ROX; MAD6; MXD6; bHLHd3
UniProt Protein Name
Max-binding protein MNT
UniProt Synonym Protein Names
Class D basic helix-loop-helix protein 3; bHLHd3; Myc antagonist MNT; Protein ROX
Protein Family
UniProt Gene Name
MNT
UniProt Synonym Gene Names
BHLHD3; ROX; bHLHd3
UniProt Entry Name
MNT_HUMAN
NCBI Protein Information
max-binding protein MNT; myc antagonist MNT; MAX binding protein; Max-interacting protein; MNT, MAX dimerization protein; class D basic helix-loop-helix protein 3

NCBI Summary for MNT

The Myc/Max/Mad network comprises a group of transcription factors that co-interact to regulate gene-specific transcriptional activation or repression. This gene encodes a protein member of the Myc/Max/Mad network. This protein has a basic-Helix-Loop-Helix-zipper domain (bHLHzip) with which it binds the canonical DNA sequence CANNTG, known as the E box, following heterodimerization with Max proteins. This protein is likely a transcriptional repressor and an antagonist of Myc-dependent transcriptional activation and cell growth. This protein represses transcription by binding to DNA binding proteins at its N-terminal Sin3-interaction domain. [provided by RefSeq, Jul 2008]
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UniProt Comments for MNT

MNT: Binds DNA as a heterodimer with MAX and represses transcription. Binds to the canonical E box sequence 5'-CACGTG-3' and, with higher affinity, to 5'-CACGCG-3'.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 17p13.3

Cellular Component: nucleoplasm; nucleus

Molecular Function: protein dimerization activity; transcription coactivator activity; chromatin binding; transcription factor activity; transcription corepressor activity

Biological Process: transcription from RNA polymerase II promoter; negative regulation of cell proliferation; regulation of cell cycle; multicellular organismal development; cell aging; negative regulation of transcription from RNA polymerase II promoter
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-MNT antibody

 Organ/Tissue Name  Pubmed Publications
 Embryonic Tissue Antibodies  >6 publications with MNT and Embryonic Tissue
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