• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

Angiopoietin-4 (ANGPT4) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS822163

MBS822163 is an antibody targeting ANGPT4. Also known as Anti-Angiopoietin-4 Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit. Rabbit polyclonal antibody to Angiopoietin-4 More details

$225 / 0.03 mL +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Angiopoietin-4 (ANGPT4), Polyclonal Antibody
Full Product Name
Anti-Angiopoietin-4 Antibody
Product Gene Name
anti-ANGPT4 antibody
Product Synonym Names
ANG3; ANG4; ANG-4; Angiopoietin-3; ANG-3
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purity/Purification
The antibody was purified by immunogen affinity chromatography.
Specificity
Recognizes endogenous levels of Angiopoietin-4 protein.
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
Antibody/Peptide Pairs
Angiopoietin-4 peptide (MBS824079) is used for blocking the activity of Angiopoietin-4 antibody (MBS822163)
Molecular Weight
46,416 Da
OMIM
603705
3D Structure
ModBase 3D Structure for Q9Y264
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human Angiopoietin-4. The exact sequence is proprietary.
Applications Tested/Suitable for anti-ANGPT4 antibody
Western Blot (WB)
Application Notes for anti-ANGPT4 antibody
WB (1/500 - 1/1000)

Western Blot (WB) of anti-ANGPT4 antibody

Western blot analysis of Angiopoietin-4 expression in HEK293T (A), mouse lung (B), PC12 (C) whole cell lysates.
Rabbit Anti-ANGPT4 Polyclonal Antibody – Cat# MBS822163

Other Notes

Small volumes of anti-ANGPT4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ANGPT4. It may not necessarily be applicable to this product.

NCBI GI #
7705276
NCBI GeneID
51378
NCBI Accession #
NP_057069.1
UniProt Primary Accession #
Q9Y264
UniProt Secondary Accession #
Q5TFF4; Q9H4Z4; B4E3J9
UniProt Related Accession #
Q9Y264
GenBank Nucleotide #
NM_015985.2
NCBI Official Full Name
angiopoietin-4
NCBI Official Synonym Full Names
angiopoietin 4
NCBI Official Symbol
ANGPT4
NCBI Official Synonym Symbols
AGP4; ANG4; ANG-3
UniProt Protein Name
Angiopoietin-4
UniProt Synonym Protein Names
Angiopoietin-3; ANG-3
Protein Family
Angiopoietin
UniProt Gene Name
ANGPT4
UniProt Synonym Gene Names
ANG3; ANG4; ANG-4; ANG-3
UniProt Entry Name
ANGP4_HUMAN
NCBI Protein Information
angiopoietin-4; ANG-4; angiopoietin-3; dJ824F16.2 (angiopoietin 4)

NCBI Summary for ANGPT4

Angiopoietins are proteins with important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The mechanism by which they contribute to angiogenesis is thought to involve regulation of endothelial cell interactions with supporting perivascular cells. The protein encoded by this gene functions as an agonist and is an angiopoietin. [provided by RefSeq, Jul 2008]
Show more

UniProt Comments for ANGPT4

ANGPT4: Binds to TEK/TIE2, modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2. Promotes endothelial cell survival, migration and angiogenesis.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 20p13

Cellular Component: extracellular space; extracellular region

Molecular Function: transmembrane receptor protein tyrosine kinase activator activity; receptor tyrosine kinase binding

Biological Process: negative regulation of angiogenesis; positive regulation of angiogenesis; positive regulation of peptidyl-tyrosine phosphorylation; transmembrane receptor protein tyrosine kinase activation (dimerization); endothelial cell proliferation; positive regulation of blood vessel endothelial cell migration; angiogenesis; negative regulation of blood vessel endothelial cell migration; blood coagulation; leukocyte migration; negative regulation of apoptosis
Show more

Research Articles on ANGPT4

1. acute-phase protein A1AT is a physiological regulator of angptl4, another acute-phase protein.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-ANGPT4 antibody

 Reference Product  PubMed Publications
 ANGPT2 antibody  >5 publications with ANGPT4 and ANGPT2
 LPL antibody  >1 publications with ANGPT4 and LPL
 TIE1 antibody  >1 publications with ANGPT4 and TIE1
 TEK antibody  >1 publications with ANGPT4 and TEK

Pathways associated with anti-ANGPT4 antibody

 Products by Pathway  Pathway Diagram
 Angiopoietin Receptor Tie2-mediated Signaling Pathway antibodies  Angiopoietin Receptor Tie2-mediated Signaling Pathway Diagram
 Cell Surface Interactions At The Vascular Wall Pathway antibodies  Cell Surface Interactions At The Vascular Wall Pathway Diagram
 HIF-1 Signaling Pathway antibodies  HIF-1 Signaling Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
 PI3K-Akt Signaling Pathway antibodies  PI3K-Akt Signaling Pathway Diagram
 PI3K-Akt Signaling Pathway antibodies  PI3K-Akt Signaling Pathway Diagram
 Rap1 Signaling Pathway antibodies  Rap1 Signaling Pathway Diagram
 Rap1 Signaling Pathway antibodies  Rap1 Signaling Pathway Diagram
 Ras Signaling Pathway antibodies  Ras Signaling Pathway Diagram
 Tie2 Signaling Pathway antibodies  Tie2 Signaling Pathway Diagram

Diseases associated with anti-ANGPT4 antibody

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >2 publications with ANGPT4 and Inflammation
 Nervous System Diseases Antibodies  >1 publications with ANGPT4 and Nervous System Diseases
 Cardiovascular Diseases Antibodies  >1 publications with ANGPT4 and Cardiovascular Diseases
 Atherosclerosis Antibodies  >1 publications with ANGPT4 and Atherosclerosis

Organs/Tissues associated with anti-ANGPT4 antibody

 Organ/Tissue Name  Pubmed Publications
 Uterus Antibodies  >2 publications with ANGPT4 and Uterus
 Placenta Antibodies  >2 publications with ANGPT4 and Placenta
 Testis Antibodies  >1 publications with ANGPT4 and Testis
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000